Details for: ACP3

Gene ID: 55

Symbol: ACP3

Ensembl ID: ENSG00000014257

Description: acid phosphatase 3

Associated with

Other Information

Genular Protein ID: 3414278605

Symbol: PPAP_HUMAN

Name: 5'-nucleotidase

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1375464

Title: Structure of human prostatic acid phosphatase gene.

PubMed ID: 1375464

DOI: 10.1016/s0006-291x(05)80048-8

PubMed ID: 1989985

Title: Covalent structure, disulfide bonding, and identification of reactive surface and active site residues of human prostatic acid phosphatase.

PubMed ID: 1989985

DOI: 10.1016/s0021-9258(18)52245-6

PubMed ID: 2712834

Title: Human prostatic acid phosphatase: cDNA cloning, gene mapping and protein sequence homology with lysosomal acid phosphatase.

PubMed ID: 2712834

DOI: 10.1016/0006-291x(89)91623-9

PubMed ID: 2842184

Title: Molecular cloning and sequence analysis of cDNA encoding human prostatic acid phosphatase.

PubMed ID: 2842184

DOI: 10.1016/0014-5793(88)80037-1

PubMed ID: 2395659

Title: Nucleotide sequence of human prostatic acid phosphatase determined from a full-length cDNA clone.

PubMed ID: 2395659

DOI: 10.1093/nar/18.16.4928

PubMed ID: 7951074

Title: Nucleotide sequence of human prostatic acid phosphatase ACPP gene, including seven Alu repeats.

PubMed ID: 7951074

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3674882

Title: Structures of the carbohydrate moieties of human prostatic acid phosphatase elucidated by H1 nuclear magnetic resonance spectroscopy.

PubMed ID: 3674882

DOI: 10.1016/0003-9861(87)90361-4

PubMed ID: 9584846

Title: Covalent modification and site-directed mutagenesis of an active site tryptophan of human prostatic acid phosphatase.

PubMed ID: 9584846

PubMed ID: 10506173

Title: Isolation of a cDNA encoding human lysophosphatidic acid phosphatase that is involved in the regulation of mitochondrial lipid biosynthesis.

PubMed ID: 10506173

DOI: 10.1074/jbc.274.41.29172

PubMed ID: 15280042

Title: Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma.

PubMed ID: 15280042

DOI: 10.1016/j.febslet.2004.06.083

PubMed ID: 17638863

Title: Prostatic acid phosphatase is not a prostate specific target.

PubMed ID: 17638863

DOI: 10.1158/0008-5472.can-07-1651

PubMed ID: 18083097

Title: Semen-derived amyloid fibrils drastically enhance HIV infection.

PubMed ID: 18083097

DOI: 10.1016/j.cell.2007.10.014

PubMed ID: 17897319

Title: Integral and associated lysosomal membrane proteins.

PubMed ID: 17897319

DOI: 10.1111/j.1600-0854.2007.00643.x

PubMed ID: 19403677

Title: Fibrils of prostatic acid phosphatase fragments boost infections with XMRV (xenotropic murine leukemia virus-related virus), a human retrovirus associated with prostate cancer.

PubMed ID: 19403677

DOI: 10.1128/jvi.00268-09

PubMed ID: 19451623

Title: The main green tea polyphenol epigallocatechin-3-gallate counteracts semen-mediated enhancement of HIV infection.

PubMed ID: 19451623

DOI: 10.1073/pnas.0811827106

PubMed ID: 19897482

Title: Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection).

PubMed ID: 19897482

DOI: 10.1074/jbc.m109.066167

PubMed ID: 20498373

Title: Human prostatic acid phosphatase, an authentic tyrosine phosphatase, dephosphorylates ErbB-2 and regulates prostate cancer cell growth.

PubMed ID: 20498373

DOI: 10.1074/jbc.m109.098301

PubMed ID: 21487525

Title: Prostatic acid phosphatase expression in human tissues.

PubMed ID: 21487525

PubMed ID: 9804805

Title: Structural origins of L(+)-tartrate inhibition of human prostatic acid phosphatase.

PubMed ID: 9804805

DOI: 10.1074/jbc.273.46.30406

PubMed ID: 10639192

Title: Crystal structure of human prostatic acid phosphatase.

PubMed ID: 10639192

DOI: 10.1002/(sici)1097-0045(20000215)42:3<211::aid-pros7>3.0.co;2-u

PubMed ID: 12525165

Title: Crystal structures of human prostatic acid phosphatase in complex with a phosphate ion and alpha-benzylaminobenzylphosphonic acid update the mechanistic picture and offer new insights into inhibitor design.

PubMed ID: 12525165

DOI: 10.1021/bi0265067

PubMed ID: 19995078

Title: NMR structure in a membrane environment reveals putative amyloidogenic regions of the SEVI precursor peptide PAP(248-286).

PubMed ID: 19995078

DOI: 10.1021/ja908170s

Sequence Information:

  • Length: 386
  • Mass: 44566
  • Checksum: EF81E11DFAECADEA
  • Sequence:
  • MRAAPLLLAR AASLSLGFLF LLFFWLDRSV LAKELKFVTL VFRHGDRSPI DTFPTDPIKE 
    SSWPQGFGQL TQLGMEQHYE LGEYIRKRYR KFLNESYKHE QVYIRSTDVD RTLMSAMTNL 
    AALFPPEGVS IWNPILLWQP IPVHTVPLSE DQLLYLPFRN CPRFQELESE TLKSEEFQKR 
    LHPYKDFIAT LGKLSGLHGQ DLFGIWSKVY DPLYCESVHN FTLPSWATED TMTKLRELSE 
    LSLLSLYGIH KQKEKSRLQG GVLVNEILNH MKRATQIPSY KKLIMYSAHD TTVSGLQMAL 
    DVYNGLLPPY ASCHLTELYF EKGEYFVEMY YRNETQHEPY PLMLPGCSPS CPLERFAELV 
    GPVIPQDWST ECMTTNSHQG TEDSTD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.