Details for: AUP1

Gene ID: 550

Symbol: AUP1

Ensembl ID: ENSG00000115307

Description: AUP1 lipid droplet regulating VLDL assembly factor

Associated with

Other Information

Genular Protein ID: 4288265857

Symbol: AUP1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11042152

Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.

PubMed ID: 11042152

DOI: 10.1101/gr.140200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12042322

Title: Ancient ubiquitous protein 1 binds to the conserved membrane-proximal sequence of the cytoplasmic tail of the integrin alpha subunits that plays a crucial role in the inside-out signaling of alpha IIbbeta 3.

PubMed ID: 12042322

DOI: 10.1074/jbc.m204340200

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18711132

Title: SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins.

PubMed ID: 18711132

DOI: 10.1073/pnas.0805371105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21127063

Title: Ancient ubiquitous protein 1 (AUP1) localizes to lipid droplets and binds the E2 ubiquitin conjugase G2 (Ube2g2) via its G2 binding region.

PubMed ID: 21127063

DOI: 10.1074/jbc.m110.190785

PubMed ID: 21857022

Title: Dual role of ancient ubiquitous protein 1 (AUP1) in lipid droplet accumulation and endoplasmic reticulum (ER) protein quality control.

PubMed ID: 21857022

DOI: 10.1074/jbc.m111.284794

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23197321

Title: Monotopic topology is required for lipid droplet targeting of ancient ubiquitous protein 1.

PubMed ID: 23197321

DOI: 10.1194/jlr.m033852

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23223569

Title: Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes.

PubMed ID: 23223569

DOI: 10.1091/mbc.e12-07-0564

PubMed ID: 24039768

Title: Monoubiquitination of ancient ubiquitous protein 1 promotes lipid droplet clustering.

PubMed ID: 24039768

DOI: 10.1371/journal.pone.0072453

PubMed ID: 28183703

Title: AUP1 (Ancient Ubiquitous Protein 1) Is a Key Determinant of Hepatic Very-Low-Density Lipoprotein Assembly and Secretion.

PubMed ID: 28183703

DOI: 10.1161/atvbaha.117.309000

PubMed ID: 29902443

Title: Flaviviruses Exploit the Lipid Droplet Protein AUP1 to Trigger Lipophagy and Drive Virus Production.

PubMed ID: 29902443

DOI: 10.1016/j.chom.2018.05.005

Sequence Information:

  • Length: 410
  • Mass: 45787
  • Checksum: 1A06476225C5DFDC
  • Sequence:
  • MELPSGPGPE RLFDSHRLPG DCFLLLVLLL YAPVGFCLLV LRLFLGIHVF LVSCALPDSV 
    LRRFVVRTMC AVLGLVARQE DSGLRDHSVR VLISNHVTPF DHNIVNLLTT CSTPLLNSPP 
    SFVCWSRGFM EMNGRGELVE SLKRFCASTR LPPTPLLLFP EEEATNGREG LLRFSSWPFS 
    IQDVVQPLTL QVQRPLVSVT VSDASWVSEL LWSLFVPFTV YQVRWLRPVH RQLGEANEEF 
    ALRVQQLVAK ELGQTGTRLT PADKAEHMKR QRHPRLRPQS AQSSFPPSPG PSPDVQLATL 
    AQRVKEVLPH VPLGVIQRDL AKTGCVDLTI TNLLEGAVAF MPEDITKGTQ SLPTASASKF 
    PSSGPVTPQP TALTFAKSSW ARQESLQERK QALYEYARRR FTERRAQEAD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.