Details for: PHIP

Gene ID: 55023

Symbol: PHIP

Ensembl ID: ENSG00000146247

Description: pleckstrin homology domain interacting protein

Associated with

Other Information

Genular Protein ID: 876936571

Symbol: PHIP_HUMAN

Name: PH-interacting protein

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 17636024

Title: Identification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survival.

PubMed ID: 17636024

DOI: 10.1128/mcb.02409-06

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 11018022

Title: Cloning and characterization of PHIP, a novel insulin receptor substrate-1 pleckstrin homology domain interacting protein.

PubMed ID: 11018022

DOI: 10.1074/jbc.c000611200

PubMed ID: 12242307

Title: The pleckstrin homology (PH) domain-interacting protein couples the insulin receptor substrate 1 PH domain to insulin signaling pathways leading to mitogenesis and GLUT4 translocation.

PubMed ID: 12242307

DOI: 10.1128/mcb.22.20.7325-7336.2002

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21834987

Title: Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration.

PubMed ID: 21834987

DOI: 10.1186/1741-7007-9-54

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25593309

Title: Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

PubMed ID: 25593309

DOI: 10.1101/gad.252189.114

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 22464331

Title: Histone recognition and large-scale structural analysis of the human bromodomain family.

PubMed ID: 22464331

DOI: 10.1016/j.cell.2012.02.013

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 23033978

Title: Diagnostic exome sequencing in persons with severe intellectual disability.

PubMed ID: 23033978

DOI: 10.1056/nejmoa1206524

PubMed ID: 27900362

Title: De novo PHIP-predicted deleterious variants are associated with developmental delay, intellectual disability, obesity, and dysmorphic features.

PubMed ID: 27900362

DOI: 10.1101/mcs.a001172

PubMed ID: 29209020

Title: A genotype-first approach identifies an intellectual disability-overweight syndrome caused by PHIP haploinsufficiency.

PubMed ID: 29209020

DOI: 10.1038/s41431-017-0039-5

Sequence Information:

  • Length: 1821
  • Mass: 206689
  • Checksum: 88688EF8743C980F
  • Sequence:
  • MSCERKGLSE LRSELYFLIA RFLEDGPCQQ AAQVLIREVA EKELLPRRTD WTGKEHPRTY 
    QNLVKYYRHL APDHLLQICH RLGPLLEQEI PQSVPGVQTL LGAGRQSLLR TNKSCKHVVW 
    KGSALAALHC GRPPESPVNY GSPPSIADTL FSRKLNGKYR LERLVPTAVY QHMKMHKRIL 
    GHLSSVYCVT FDRTGRRIFT GSDDCLVKIW ATDDGRLLAT LRGHAAEISD MAVNYENTMI 
    AAGSCDKMIR VWCLRTCAPL AVLQGHSASI TSLQFSPLCS GSKRYLSSTG ADGTICFWLW 
    DAGTLKINPR PAKFTERPRP GVQMICSSFS AGGMFLATGS TDHIIRVYFF GSGQPEKISE 
    LEFHTDKVDS IQFSNTSNRF VSGSRDGTAR IWQFKRREWK SILLDMATRP AGQNLQGIED 
    KITKMKVTMV AWDRHDNTVI TAVNNMTLKV WNSYTGQLIH VLMGHEDEVF VLEPHPFDPR 
    VLFSAGHDGN VIVWDLARGV KIRSYFNMIE GQGHGAVFDC KCSPDGQHFA CTDSHGHLLI 
    FGFGSSSKYD KIADQMFFHS DYRPLIRDAN NFVLDEQTQQ APHLMPPPFL VDVDGNPHPS 
    RYQRLVPGRE NCREEQLIPQ MGVTSSGLNQ VLSQQANQEI SPLDSMIQRL QQEQDLRRSG 
    EAVISNTSRL SRGSISSTSE VHSPPNVGLR RSGQIEGVRQ MHSNAPRSEI ATERDLVAWS 
    RRVVVPELSA GVASRQEEWR TAKGEEEIKT YRSEEKRKHL TVPKENKIPT VSKNHAHEHF 
    LDLGESKKQQ TNQHNYRTRS ALEETPRPSE EIENGSSSSD EGEVVAVSGG TSEEEERAWH 
    SDGSSSDYSS DYSDWTADAG INLQPPKKVP KNKTKKAESS SDEEEESEKQ KQKQIKKEKK 
    KVNEEKDGPI SPKKKKPKER KQKRLAVGEL TENGLTLEEW LPSTWITDTI PRRCPFVPQM 
    GDEVYYFRQG HEAYVEMARK NKIYSINPKK QPWHKMELRE QELMKIVGIK YEVGLPTLCC 
    LKLAFLDPDT GKLTGGSFTM KYHDMPDVID FLVLRQQFDD AKYRRWNIGD RFRSVIDDAW 
    WFGTIESQEP LQLEYPDSLF QCYNVCWDNG DTEKMSPWDM ELIPNNAVFP EELGTSVPLT 
    DGECRSLIYK PLDGEWGTNP RDEECERIVA GINQLMTLDI ASAFVAPVDL QAYPMYCTVV 
    AYPTDLSTIK QRLENRFYRR VSSLMWEVRY IEHNTRTFNE PGSPIVKSAK FVTDLLLHFI 
    KDQTCYNIIP LYNSMKKKVL SDSEDEEKDA DVPGTSTRKR KDHQPRRRLR NRAQSYDIQA 
    WKKQCEELLN LIFQCEDSEP FRQPVDLLEY PDYRDIIDTP MDFATVRETL EAGNYESPME 
    LCKDVRLIFS NSKAYTPSKR SRIYSMSLRL SAFFEEHISS VLSDYKSALR FHKRNTITKR 
    RKKRNRSSSV SSSAASSPER KKRILKPQLK SESSTSAFST PTRSIPPRHN AAQINGKTES 
    SSVVRTRSNR VVVDPVVTEQ PSTSSAAKTF ITKANASAIP GKTILENSVK HSKALNTLSS 
    PGQSSFSHGT RNNSAKENME KEKPVKRKMK SSVLPKASTL SKSSAVIEQG DCKNNALVPG 
    TIQVNGHGGQ PSKLVKRGPG RKPKVEVNTN SGEIIHKKRG RKPKKLQYAK PEDLEQNNVH 
    PIRDEVLPSS TCNFLSETNN VKEDLLQKKN RGGRKPKRKM KTQKLDADLL VPASVKVLRR 
    SNRKKIDDPI DEEEEFEELK GSEPHMRTRN QGRRTAFYNE DDSEEEQRQL LFEDTSLTFG 
    TSSRGRVRKL TEKAKANLIG W

Genular Protein ID: 3469033357

Symbol: A0A8V8TPV5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

Sequence Information:

  • Length: 1820
  • Mass: 206602
  • Checksum: ACA8116974CF4A2B
  • Sequence:
  • MSCERKGLSE LRSELYFLIA RFLEDGPCQQ AAQVLIREVA EKELLPRRTD WTGKEHPRTY 
    QNLVKYYRHL APDHLLQICH RLGPLLEQEI PQSVPGVQTL LGAGRQSLLR TNKSCKHVVW 
    KGSALAALHC GRPPESPVNY GSPPSIADTL FSRKLNGKYR LERLVPTAVY QHMKMHKRIL 
    GHLSSVYCVT FDRTGRRIFT GSDDCLVKIW ATDDGRLLAT LRGHAAEISD MAVNYENTMI 
    AAGSCDKMIR VWCLRTCAPL AVLQGHSASI TSLQFSPLCS GSKRYLSSTG ADGTICFWLW 
    DAGTLKINPR PAKFTERPRP GVQMICSSFS AGGMFLATGS TDHIIRVYFF GSGQPEKISE 
    LEFHTDKVDS IQFSNTSNRF VSGSRDGTAR IWQFKRREWK SILLDMATRP AGQNLQGIED 
    KITKMKVTMV AWDRHDNTVI TAVNNMTLKV WNSYTGQLIH VLMGHEDEVF VLEPHPFDPR 
    VLFSAGHDGN VIVWDLARGV KIRSYFNMIE GQGHGAVFDC KCSPDGQHFA CTDSHGHLLI 
    FGFGSSSKYD KIADQMFFHS DYRPLIRDAN NFVLDEQTQQ APHLMPPPFL VDVDGNPHPS 
    RYQRLVPGRE NCREEQLIPQ MGVTSSGLNQ VLSQQANQEI SPLDSMIQRL QQEQDLRRSG 
    EAVISNTSRL SRGSISSTSE VHSPPNVGLR RSGQIEGVRQ MHSNAPRSEI ATERDLVAWS 
    RRVVVPELSA GVARQEEWRT AKGEEEIKTY RSEEKRKHLT VPKENKIPTV SKNHAHEHFL 
    DLGESKKQQT NQHNYRTRSA LEETPRPSEE IENGSSSSDE GEVVAVSGGT SEEEERAWHS 
    DGSSSDYSSD YSDWTADAGI NLQPPKKVPK NKTKKAESSS DEEEESEKQK QKQIKKEKKK 
    VNEEKDGPIS PKKKKPKERK QKRLAVGELT ENGLTLEEWL PSTWITDTIP RRCPFVPQMG 
    DEVYYFRQGH EAYVEMARKN KIYSINPKKQ PWHKMELREQ ELMKIVGIKY EVGLPTLCCL 
    KLAFLDPDTG KLTGGSFTMK YHDMPDVIDF LVLRQQFDDA KYRRWNIGDR FRSVIDDAWW 
    FGTIESQEPL QLEYPDSLFQ CYNVCWDNGD TEKMSPWDME LIPNNAVFPE ELGTSVPLTD 
    GECRSLIYKP LDGEWGTNPR DEECERIVAG INQLMTLDIA SAFVAPVDLQ AYPMYCTVVA 
    YPTDLSTIKQ RLENRFYRRV SSLMWEVRYI EHNTRTFNEP GSPIVKSAKF VTDLLLHFIK 
    DQTCYNIIPL YNSMKKKVLS DSEDEEKDAD VPGTSTRKRK DHQPRRRLRN RAQSYDIQAW 
    KKQCEELLNL IFQCEDSEPF RQPVDLLEYP DYRDIIDTPM DFATVRETLE AGNYESPMEL 
    CKDVRLIFSN SKAYTPSKRS RIYSMSLRLS AFFEEHISSV LSDYKSALRF HKRNTITKRR 
    KKRNRSSSVS SSAASSPERK KRILKPQLKS ESSTSAFSTP TRSIPPRHNA AQINGKTESS 
    SVVRTRSNRV VVDPVVTEQP STSSAAKTFI TKANASAIPG KTILENSVKH SKALNTLSSP 
    GQSSFSHGTR NNSAKENMEK EKPVKRKMKS SVLPKASTLS KSSAVIEQGD CKNNALVPGT 
    IQVNGHGGQP SKLVKRGPGR KPKVEVNTNS GEIIHKKRGR KPKKLQYAKP EDLEQNNVHP 
    IRDEVLPSST CNFLSETNNV KEDLLQKKNR GGRKPKRKMK TQKLDADLLV PASVKVLRRS 
    NRKKIDDPID EEEEFEELKG SEPHMRTRNQ GRRTAFYNED DSEEEQRQLL FEDTSLTFGT 
    SSRGRVRKLT EKAKANLIGW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.