VPS37C | ENSG00000167987 | NCBI 55048

Details for: VPS37C

Gene ID: 55048

Symbol: VPS37C

Ensembl ID: ENSG00000167987

Description: VPS37C subunit of ESCRT-I

Associated with

Assembly of the hiv virion
(R-HSA-175474)
Autophagy
(R-HSA-9612973)
Budding and maturation of hiv virion
(R-HSA-162588)
Disease
(R-HSA-1643685)
Endosomal sorting complex required for transport (escrt)
(R-HSA-917729)
Hcmv infection
(R-HSA-9609646)
Hcmv late events
(R-HSA-9610379)
Hiv infection
(R-HSA-162906)
Hiv life cycle
(R-HSA-162587)
Infectious disease
(R-HSA-5663205)
Late endosomal microautophagy
(R-HSA-9615710)
Late phase of hiv life cycle
(R-HSA-162599)
Membrane binding and targetting of gag proteins
(R-HSA-174490)
Membrane trafficking
(R-HSA-199991)
Synthesis and processing of gag, gagpol polyproteins
(R-HSA-174495)
Vesicle-mediated transport
(R-HSA-5653656)
Viral infection pathways
(R-HSA-9824446)
Calcium-dependent protein binding
(GO:0048306)
Endosome membrane
(GO:0010008)
Escrt i complex
(GO:0000813)
Extracellular exosome
(GO:0070062)
Late endosome membrane
(GO:0031902)
Macroautophagy
(GO:0016236)
Membrane fission
(GO:0090148)
Multivesicular body assembly
(GO:0036258)
Protein binding
(GO:0005515)
Protein targeting to membrane
(GO:0006612)
Protein targeting to vacuole
(GO:0006623)
Protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
(GO:0043328)
Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
(GO:0043162)
Viral budding via host escrt complex
(GO:0039702)

Other Information

Proteins

Vacuolar protein sorting-associated protein 37C

Genular Protein ID: 2190468188

Symbol: VP37C_HUMAN

Name: Vacuolar protein sorting-associated protein 37C

UniProtKB Accession Codes:

A5D8V6 Q8N3K4

Database IDs:

Citations:

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15509564

Title: Identification of human VPS37C, a component of endosomal sorting complex required for transport-I important for viral budding.

PubMed ID: 15509564

DOI: 10.1074/jbc.m410384200

PubMed ID: 18005716

Title: Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding.

PubMed ID: 18005716

DOI: 10.1016/j.chom.2007.06.003

PubMed ID: 17853893

Title: Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis.

PubMed ID: 17853893

DOI: 10.1038/sj.emboj.7601850

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21270402

Title: TANK-binding kinase 1 attenuates PTAP-dependent retroviral budding through targeting endosomal sorting complex required for transport-I.

PubMed ID: 21270402

DOI: 10.4049/jimmunol.1000262

PubMed ID: 22405001

Title: The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain.

PubMed ID: 22405001

DOI: 10.1016/j.str.2011.12.013

Sequence Information:

Length: 355
Mass: 38659
Checksum: 1DE18F0E4C7C7E2E
Sequence:

METLKDKTLQ ELEELQNDSE AIDQLALESP EVQDLQLERE MALATNRSLA ERNLEFQGPL 
EISRSNLSDR YQELRKLVER CQEQKAKLEK FSSALQPGTL LDLLQVEGMK IEEESEAMAE 
KFLEGEVPLE TFLENFSSMR MLSHLRRVRV EKLQEVVRKP RASQELAGDA PPPRPPPPVR 
PVPQGTPPVV EEQPQPPLAM PPYPLPYSPS PSLPVGPTAH GALPPAPFPV VSQPSFYSGP 
LGPTYPAAQL GPRGAAGYSW SPQRSMPPRP GYPGTPMGAS GPGYPLRGGR APSPGYPQQS 
PYPATGGKPP YPIQPQLPSF PGQPQPSVPL QPPYPPGPAP PYGFPPPPGP AWPGY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: VPS37C

Associated with

Other Information

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

Human chromosome 11 DNA sequence and analysis including novel gene identification. PubMed ID: 16554811

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification of human VPS37C, a component of endosomal sorting complex required for transport-I important for viral budding. PubMed ID: 15509564

Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding. PubMed ID: 18005716

Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis. PubMed ID: 17853893

Initial characterization of the human central proteome. PubMed ID: 21269460

TANK-binding kinase 1 attenuates PTAP-dependent retroviral budding through targeting endosomal sorting complex required for transport-I. PubMed ID: 21270402

The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain. PubMed ID: 22405001