Details for: WIPI1

Gene ID: 55062

Symbol: WIPI1

Ensembl ID: ENSG00000070540

Description: WD repeat domain, phosphoinositide interacting 1

Associated with

Other Information

Genular Protein ID: 358198387

Symbol: WIPI1_HUMAN

Name: WD repeat domain phosphoinositide-interacting protein 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15602573

Title: WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy.

PubMed ID: 15602573

DOI: 10.1038/sj.onc.1208331

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15020712

Title: PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49.

PubMed ID: 15020712

DOI: 10.1091/mbc.e03-10-0732

PubMed ID: 17618624

Title: Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy.

PubMed ID: 17618624

DOI: 10.1016/j.febslet.2007.06.040

PubMed ID: 19590496

Title: Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy.

PubMed ID: 19590496

DOI: 10.1038/emboj.2009.159

PubMed ID: 20639694

Title: Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins.

PubMed ID: 20639694

DOI: 10.4161/auto.6.6.12709

PubMed ID: 20114074

Title: AMPK-independent induction of autophagy by cytosolic Ca2+ increase.

PubMed ID: 20114074

DOI: 10.1016/j.cellsig.2010.01.015

PubMed ID: 20484055

Title: Starvation-induced hyperacetylation of tubulin is required for the stimulation of autophagy by nutrient deprivation.

PubMed ID: 20484055

DOI: 10.1074/jbc.m109.091553

PubMed ID: 20529838

Title: The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells.

PubMed ID: 20529838

DOI: 10.1074/jbc.m110.118125

PubMed ID: 20059746

Title: Modulation of local PtdIns3P levels by the PI phosphatase MTMR3 regulates constitutive autophagy.

PubMed ID: 20059746

DOI: 10.1111/j.1600-0854.2010.01034.x

PubMed ID: 21317285

Title: WIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition.

PubMed ID: 21317285

DOI: 10.1074/jbc.m110.200543

PubMed ID: 21564513

Title: Freeze-fracture replica immunolabelling reveals human WIPI-1 and WIPI-2 as membrane proteins of autophagosomes.

PubMed ID: 21564513

DOI: 10.1111/j.1582-4934.2011.01339.x

PubMed ID: 21896713

Title: Ca2+/calmodulin-dependent kinase (CaMK) signaling via CaMKI and AMP-activated protein kinase contributes to the regulation of WIPI-1 at the onset of autophagy.

PubMed ID: 21896713

DOI: 10.1124/mol.111.071761

PubMed ID: 22829830

Title: WIPI-1 positive autophagosome-like vesicles entrap pathogenic Staphylococcus aureus for lysosomal degradation.

PubMed ID: 22829830

DOI: 10.1155/2012/179207

PubMed ID: 23088497

Title: Defining regulatory and phosphoinositide-binding sites in the human WIPI-1 beta-propeller responsible for autophagosomal membrane localization downstream of mTORC1 inhibition.

PubMed ID: 23088497

DOI: 10.1186/1750-2187-7-16

PubMed ID: 28561066

Title: WIPI3 and WIPI4 beta-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy.

PubMed ID: 28561066

DOI: 10.1038/ncomms15637

PubMed ID: 31271352

Title: The autophagic membrane tether ATG2A transfers lipids between membranes.

PubMed ID: 31271352

DOI: 10.7554/elife.45777

PubMed ID: 33499712

Title: Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy.

PubMed ID: 33499712

DOI: 10.1080/15548627.2021.1874133

Sequence Information:

  • Length: 446
  • Mass: 48673
  • Checksum: 35B5650990B62E31
  • Sequence:
  • MEAEAADAPP GGVESALSCF SFNQDCTSLA TGTKAGYKLF SLSSVEQLDQ VHGSNEIPDV 
    YIVERLFSSS LVVVVSHTKP RQMNVYHFKK GTEICNYSYS SNILSIRLNR QRLLVCLEES 
    IYIHNIKDMK LLKTLLDIPA NPTGLCALSI NHSNSYLAYP GSLTSGEIVL YDGNSLKTVC 
    TIAAHEGTLA AITFNASGSK LASASEKGTV IRVFSVPDGQ KLYEFRRGMK RYVTISSLVF 
    SMDSQFLCAS SNTETVHIFK LEQVTNSRPE EPSTWSGYMG KMFMAATNYL PTQVSDMMHQ 
    DRAFATARLN FSGQRNICTL STIQKLPRLL VASSSGHLYM YNLDPQDGGE CVLIKTHSLL 
    GSGTTEENKE NDLRPSLPQS YAATVARPSA SSASTVPGYS EDGGALRGEV IPEHEFATGP 
    VCLDDENEFP PIILCRGNQK GKTKQS

Genular Protein ID: 539824007

Symbol: G5EA37_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

Sequence Information:

  • Length: 364
  • Mass: 39942
  • Checksum: E7276BF1EC1D53C4
  • Sequence:
  • MNVYHFKKGT EICNYSYSSN ILSIRLNRQR LLVCLEESIY IHNIKDMKLL KTLLDIPANP 
    TGLCALSINH SNSYLAYPGS LTSGEIVLYD GNSLKTVCTI AAHEGTLAAI TFNASGSKLA 
    SASEKGTVIR VFSVPDGQKL YEFRRGMKRY VTISSLVFSM DSQFLCASSN TETVHIFKLE 
    QVTNSRPEEP STWSGYMGKM FMAATNYLPT QVSDMMHQDR AFATARLNFS GQRNICTLST 
    IQKLPRLLVA SSSGHLYMYN LDPQDGGECV LIKTHSLLGS GTTEENKEND LRPSLPQSYA 
    ATVARPSASS ASTVPGYSED GGALRGEVIP EHEFATGPVC LDDENEFPPI ILCRGNQKGK 
    TKQS

Genular Protein ID: 3764387012

Symbol: B4DX63_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 364
  • Mass: 39878
  • Checksum: 652F434FF8512594
  • Sequence:
  • MNVYHFKKGT EICNYSYSSN ILSIRLNRQR LLVCLEESIY IHNIKDMKLL KTLLDIPANP 
    TGLCALSINH SNSYLAYPGS LTSGEIVLYD GNSLKTVCTI AAHEGTLAAI TFNASGSKLA 
    SASEKGTVIR VFSVPDGQKL YEFRRGMKRY VTISSLVFSM DSQFLCASSN TETVHIFKLE 
    QVTNSRPEEP STWSGYMGKM LMAATNYLPT QVSDMMHQDR AFATARLNFS GQRNICTLST 
    IQKLPRLLVA SSSGHLYMYN LDPQDGGECV LIKTHSLLGS GTTEENKEND LRPSLPQSYA 
    ATVARPSASS ASAVPGYSED GGALRGEVIP EHEFATGPVC LDDENEFPPI ILCRGNQKGK 
    TKQS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.