Details for: IFT57

Gene ID: 55081

Symbol: IFT57

Ensembl ID: ENSG00000114446

Description: intraflagellar transport 57

Associated with

Other Information

Genular Protein ID: 1249169428

Symbol: IFT57_HUMAN

Name: Intraflagellar transport protein 57 homolog

UniProtKB Accession Codes:

Q9NWB7 Q96DA9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 24 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11788820

Title: Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi.

PubMed ID: 11788820

DOI: 10.1038/ncb735

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12745083

Title: The viral death protein Apoptin interacts with Hippi, the protein interactor of Huntingtin-interacting protein 1.

PubMed ID: 12745083

DOI: 10.1016/s0006-291x(03)00764-2

PubMed ID: 14502241

Title: Bifunctional apoptosis inhibitor (BAR) protects neurons from diverse cell death pathways.

PubMed ID: 14502241

DOI: 10.1038/sj.cdd.4401287

PubMed ID: 17107665

Title: Homer1c interacts with Hippi and protects striatal neurons from apoptosis.

PubMed ID: 17107665

DOI: 10.1016/j.bbrc.2006.10.167

PubMed ID: 17173859

Title: Interaction of HIPPI with putative promoter sequence of caspase-1 in vitro and in vivo.

PubMed ID: 17173859

DOI: 10.1016/j.bbrc.2006.11.138

PubMed ID: 17623017

Title: Interactions of HIPPI, a molecular partner of Huntingtin interacting protein HIP1, with the specific motif present at the putative promoter sequence of the caspase-1, caspase-8 and caspase-10 genes.

PubMed ID: 17623017

DOI: 10.1111/j.1742-4658.2007.05922.x

PubMed ID: 25860617

Title: Characterization of tetratricopeptide repeat-containing proteins critical for cilia formation and function.

PubMed ID: 25860617

DOI: 10.1371/journal.pone.0124378

PubMed ID: 27060890

Title: Autosomal recessive IFT57 hypomorphic mutation cause ciliary transport defect in unclassified oral-facial-digital syndrome with short stature and brachymesophalangia.

PubMed ID: 27060890

DOI: 10.1111/cge.12785

PubMed ID: 31637240

Title: SANS (USH1G) Molecularly Links the Human Usher Syndrome Protein Network to the Intraflagellar Transport Module by Direct Binding to IFT-B Proteins.

PubMed ID: 31637240

DOI: 10.3389/fcell.2019.00216

Sequence Information:

  • Length: 429
  • Mass: 49108
  • Checksum: D80200D957AE5AC4
  • Sequence:
    • MTAALAVVTT SGLEDGVPRS RGEGTGEVVL ERGPGAAYHM FVVMEDLVEK LKLLRYEEEF 
LRKSNLKAPS RHYFALPTNP GEQFYMFCTL AAWLINKAGR PFEQPQEYDD PNATISNILS 
ELRSFGRTAD FPPSKLKSGY GEHVCYVLDC FAEEALKYIG FTWKRPIYPV EELEEESVAE 
DDAELTLNKV DEEFVEEETD NEENFIDLNV LKAQTYHLDM NETAKQEDIL ESTTDAAEWS 
LEVERVLPQL KVTIRTDNKD WRIHVDQMHQ HRSGIESALK ETKGFLDKLH NEITRTLEKI 
SSREKYINNQ LENLVQEYRA AQAQLSEAKE RYQQGNGGVT ERTRLLSEVM EELEKVKQEM 
EEKGSSMTDG APLVKIKQSL TKLKQETVEM DIRIGIVEHT LLQSKLKEKS NMTRNMHATV 
IPEPATGFY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.