Details for: AVP

Gene ID: 551

Symbol: AVP

Ensembl ID: ENSG00000101200

Description: arginine vasopressin

Associated with

Other Information

Genular Protein ID: 1447799280

Symbol: NEU2_HUMAN

Name: Vasopressin-neurophysin 2-copeptin

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2991279

Title: The human vasopressin gene is linked to the oxytocin gene and is selectively expressed in a cultured lung cancer cell line.

PubMed ID: 2991279

DOI: 10.1016/s0021-9258(17)39236-0

PubMed ID: 3768139

Title: The neurohypophyseal hormones vasopressin and oxytocin. Precursor structure, synthesis and regulation.

PubMed ID: 3768139

DOI: 10.1515/bchm3.1986.367.2.695

PubMed ID: 4065330

Title: Expression of the vasopressin and oxytocin genes in human hypothalami.

PubMed ID: 4065330

DOI: 10.1016/0014-5793(85)80069-7

PubMed ID: 1740104

Title: A missense mutation in the vasopressin-neurophysin precursor gene cosegregates with human autosomal dominant neurohypophyseal diabetes insipidus.

PubMed ID: 1740104

DOI: 10.1002/j.1460-2075.1992.tb05022.x

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 13591312

Title: On the nature of oxytocin and vasopressin from human pituitary.

PubMed ID: 13591312

DOI: 10.3181/00379727-98-24154

PubMed ID: 6574452

Title: Identification of human neurophysins: complete amino acid sequences of MSEL- and VLDV-neurophysins.

PubMed ID: 6574452

DOI: 10.1073/pnas.80.10.2839

PubMed ID: 7271787

Title: The complete sequence of a novel human pituitary glycopeptide homologous to pig posterior pituitary glycopeptide.

PubMed ID: 7271787

DOI: 10.1016/s0006-291x(81)80258-6

PubMed ID: 33713620

Title: Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system.

PubMed ID: 33713620

DOI: 10.1016/j.cell.2021.02.053

PubMed ID: 8370682

Title: Familial neurohypophyseal diabetes insipidus associated with a signal peptide mutation.

PubMed ID: 8370682

DOI: 10.1210/jcem.77.3.8370682

PubMed ID: 8103767

Title: Glu-47, which forms a salt bridge between neurophysin-II and arginine vasopressin, is deleted in patients with familial central diabetes insipidus.

PubMed ID: 8103767

DOI: 10.1210/jcem.77.3.8103767

PubMed ID: 8514868

Title: Possible involvement of inefficient cleavage of preprovasopressin by signal peptidase as a cause for familial central diabetes insipidus.

PubMed ID: 8514868

DOI: 10.1172/jci116494

PubMed ID: 8045958

Title: A de novo mutation in the coding sequence for neurophysin-II (Pro24-->Leu) is associated with onset and transmission of autosomal dominant neurohypophyseal diabetes insipidus.

PubMed ID: 8045958

DOI: 10.1210/jcem.79.2.8045958

PubMed ID: 7714110

Title: Two novel mutations in the coding region for neurophysin-II associated with familial central diabetes insipidus.

PubMed ID: 7714110

DOI: 10.1210/jcem.80.4.7714110

PubMed ID: 8554046

Title: Identification of 13 new mutations in the vasopressin-neurophysin II gene in 17 kindreds with familial autosomal dominant neurohypophyseal diabetes insipidus.

PubMed ID: 8554046

PubMed ID: 9360520

Title: Autosomal dominant neurohypophyseal diabetes insipidus associated with a missense mutation encoding Gly23-->Val in neurophysin II.

PubMed ID: 9360520

DOI: 10.1210/jcem.82.11.4231

PubMed ID: 9580132

Title: Identification of a novel nonsense mutation and a missense substitution in the vasopressin-neurophysin II gene in two Spanish kindreds with familial neurohypophyseal diabetes insipidus.

PubMed ID: 9580132

DOI: 10.1210/jcem.83.3.4658

PubMed ID: 9814475

Title: Two novel mutations of the vasopressin gene associated with familial diabetes insipidus and identification of an asymptomatic carrier infant.

PubMed ID: 9814475

DOI: 10.1210/jcem.83.11.5278

PubMed ID: 10369876

Title: Autosomal recessive familial neurohypophyseal diabetes insipidus with continued secretion of mutant weakly active vasopressin.

PubMed ID: 10369876

DOI: 10.1093/hmg/8.7.1303

PubMed ID: 10487710

Title: Molecular analysis in familial neurohypophyseal diabetes insipidus: early diagnosis of an asymptomatic carrier.

PubMed ID: 10487710

DOI: 10.1210/jcem.84.9.5979

PubMed ID: 11017955

Title: Identification of two distinct mutations at the same nucleotide position, concomitantly with a novel polymorphism in the vasopressin-neurophysin II gene (AVP-NP II) in two Dutch families with familial neurohypophyseal diabetes insipidus.

PubMed ID: 11017955

PubMed ID: 11150885

Title: A novel arginine vasopressin-neurophysin II mutation causes autosomal dominant neurohypophyseal diabetes insipidus and morphologic pituitary changes.

PubMed ID: 11150885

DOI: 10.1159/000023573

PubMed ID: 10677561

Title: Familial neurohypophyseal diabetes insipidus associated with a novel mutation in the vasopressin-neurophysin II gene.

PubMed ID: 10677561

DOI: 10.3892/ijmm.5.3.229

PubMed ID: 11748489

Title: A new mutation of the arginine vasopressin-neurophysin II gene in a family with autosomal dominant neurohypophyseal diabetes insipidus.

PubMed ID: 11748489

DOI: 10.1055/s-2001-18994

PubMed ID: 11443218

Title: Familial neurohypophysial diabetes insipidus in a large Dutch kindred: effect of the onset of diabetes on growth in children and cell biological defects of the mutant vasopressin prohormone.

PubMed ID: 11443218

DOI: 10.1210/jcem.86.7.7686

PubMed ID: 11161827

Title: A missense mutation encoding cys(67) --> gly in neurophysin ii is associated with early onset autosomal dominant neurohypophyseal diabetes insipidus.

PubMed ID: 11161827

DOI: 10.1006/mgme.2000.3117

PubMed ID: 11980620

Title: Clinical and molecular analysis of three families with autosomal dominant neurohypophyseal diabetes insipidus associated with a novel and recurrent mutations in the vasopressin-neurophysin II gene.

PubMed ID: 11980620

DOI: 10.1530/eje.0.1460649

PubMed ID: 12012274

Title: Identification of a novel mutation in the arginine vasopressin-neurophysin II gene in familial central diabetes insipidus.

PubMed ID: 12012274

DOI: 10.1055/s-2002-29091

PubMed ID: 12107248

Title: Autosomal dominant neurohypophyseal diabetes insipidus due to substitution of histidine for tyrosine-2 in the vasopressin moiety of the hormone precursor.

PubMed ID: 12107248

DOI: 10.1210/jcem.87.7.8677

PubMed ID: 12359138

Title: A missense mutation encoding Cys73Phe in neurophysin II is associated with autosomal dominant neurohypophyseal diabetes insipidus.

PubMed ID: 12359138

DOI: 10.1016/s1096-7192(02)00118-x

PubMed ID: 12519420

Title: A signal peptide mutation of the arginine vasopressin gene in monozygotic twins.

PubMed ID: 12519420

DOI: 10.1046/j.1365-2265.2003.01667.x

PubMed ID: 14510916

Title: Progressive decline of vasopressin secretion in familial autosomal dominant neurohypophyseal diabetes insipidus presenting a novel mutation in the vasopressin-neurophysin II gene.

PubMed ID: 14510916

DOI: 10.1046/j.1365-2265.2003.01834.x

PubMed ID: 12931042

Title: A new missense mutation of the vasopressin-neurophysin II gene in a family with neurohypophyseal diabetes insipidus.

PubMed ID: 12931042

DOI: 10.1159/000072526

PubMed ID: 15538939

Title: Identification of a novel mutation in the arginine vasopressin-neurophysin II gene affecting the sixth intrachain disulfide bridge of the neurophysin II moiety.

PubMed ID: 15538939

DOI: 10.1530/eje.0.1510605

PubMed ID: 14673472

Title: Six novel mutations in the arginine vasopressin gene in 15 kindreds with autosomal dominant familial neurohypophyseal diabetes insipidus give further insight into the pathogenesis.

PubMed ID: 14673472

DOI: 10.1038/sj.ejhg.5201086

PubMed ID: 18174156

Title: Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptides.

PubMed ID: 18174156

DOI: 10.1074/jbc.m706477200

Sequence Information:

  • Length: 164
  • Mass: 17325
  • Checksum: 8F5EF9834700B9AE
  • Sequence:
  • MPDTMLPACF LGLLAFSSAC YFQNCPRGGK RAMSDLELRQ CLPCGPGGKG RCFGPSICCA 
    DELGCFVGTA EALRCQEENY LPSPCQSGQK ACGSGGRCAA FGVCCNDESC VTEPECREGF 
    HRRARASDRS NATQLDGPAG ALLLRLVQLA GAPEPFEPAQ PDAY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.