Details for: DYNC2I1

Gene ID: 55112

Symbol: DYNC2I1

Ensembl ID: ENSG00000126870

Description: dynein 2 intermediate chain 1

Associated with

Other Information

Genular Protein ID: 1374459634

Symbol: DC2I1_HUMAN

Name: Cytoplasmic dynein 2 intermediate chain 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25205765

Title: Subunit composition of the human cytoplasmic dynein-2 complex.

PubMed ID: 25205765

DOI: 10.1242/jcs.159038

PubMed ID: 25492405

Title: Whole exome sequencing is an efficient, sensitive and specific method for determining the genetic cause of short-rib thoracic dystrophies.

PubMed ID: 25492405

DOI: 10.1111/cge.12550

PubMed ID: 26044572

Title: TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport.

PubMed ID: 26044572

DOI: 10.1038/ncomms8074

PubMed ID: 27021811

Title:

PubMed ID: 27021811

DOI: 10.1038/ncomms11270

PubMed ID: 23910462

Title: Short-rib polydactyly and Jeune syndromes are caused by mutations in WDR60.

PubMed ID: 23910462

DOI: 10.1016/j.ajhg.2013.06.022

PubMed ID: 29742051

Title: Interaction of WDR60 intermediate chain with TCTEX1D2 light chain of the dynein-2 complex is crucial for ciliary protein trafficking.

PubMed ID: 29742051

DOI: 10.1091/mbc.e18-03-0173

PubMed ID: 30320547

Title: Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function.

PubMed ID: 30320547

DOI: 10.7554/elife.39655

PubMed ID: 30649997

Title: Interactions of the dynein-2 intermediate chain WDR34 with the light chains are required for ciliary retrograde protein trafficking.

PubMed ID: 30649997

DOI: 10.1091/mbc.e18-10-0678

PubMed ID: 31451806

Title: Structure of the dynein-2 complex and its assembly with intraflagellar transport trains.

PubMed ID: 31451806

DOI: 10.1038/s41594-019-0286-y

Sequence Information:

  • Length: 1066
  • Mass: 122571
  • Checksum: A6B4A0C3DC4CD2C2
  • Sequence:
  • MEPGKRRTKD DTWKADDLRK HLWAIQSGGS KEERKHREKK LRKESEMDLP EHKEPRCRDP 
    DQDARSRDRV AEVHTAKESP RGERDRDRQR ERRRDAKDRE KEKLKEKHRE AEKSHSRGKD 
    REKEKDRRAR KEELRQTVAH HNLLGQETRD RQLLERAERK GRSVSKVRSE EKDEDSERGD 
    EDRERRYRER KLQYGDSKDN PLKYWLYKEE GERRHRKPRE PDRDNKHREK SSTREKREKY 
    SKEKSNSFSD KGEERHKEKR HKEGFHFDDE RHQSNVDRKE KSAKDEPRKR ESQNGEHRNR 
    GASSKRDGTS SQHAENLVRN HGKDKDSRRK HGHEEGSSVW WKLDQRPGGE ETVEIEKEET 
    DLENARADAY TASCEDDFED YEDDFEVCDG DDDESSNEPE SREKLEELPL AQKKEIQEIQ 
    RAINAENERI GELSLKLFQK RGRTEFEKEP RTDTNSSPSR ASVCGIFVDF ASASHRQKSR 
    TQALKQKMRS TKLLRLIDLD FSFTFSLLDL PPVNEYDMYI RNFGKKNTKQ AYVQCNEDNV 
    ERDIQTEEIE TREVWTQHPG ESTVVSGGSE QRDTSDAVVM PKIDTPRLCS FLRAACQVMA 
    VLLEEDRLAA EPSWNLRAQD RALYFSDSSS QLNTSLPFLQ NRKVSSLHTS RVQRQMVVSV 
    HDLPEKSFVP LLDSKYVLCV WDIWQPSGPQ KVLICESQVT CCCLSPLKAF LLFAGTAHGS 
    VVVWDLREDS RLHYSVTLSD GFWTFRTATF STDGILTSVN HRSPLQAVEP ISTSVHKKQS 
    FVLSPFSTQE EMSGLSFHIA SLDESGVLNV WVVVELPKAD IAGSISDLGL MPGGRVKLVH 
    SALIQLGDSL SHKGNEFWGT TQTLNVKFLP SDPNHFIIGT DMGLISHGTR QDLRVAPKLF 
    KPQQHGIRPV KVNVIDFSPF GEPIFLAGCS DGSIRLHQLS SAFPLLQWDS STDSHAVTGL 
    QWSPTRPAVF LVQDDTSNIY IWDLLQSDLG PVAKQQVSPN RLVAMAAVGE PEKAGGSFLA 
    LVLARASGSI DIQHLKRRWA APEVDECNRL RLLLQEALWP EGKLHK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.