Details for: FANCL
Associated with
Other Information
Genular Protein ID: 3412357492
Symbol: FANCL_HUMAN
Name: E3 ubiquitin-protein ligase FANCL
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12724401
Title: A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome.
PubMed ID: 12724401
PubMed ID: 12973351
Title: A novel ubiquitin ligase is deficient in Fanconi anemia.
PubMed ID: 12973351
DOI: 10.1038/ng1241
PubMed ID: 15502827
Title: X-linked inheritance of Fanconi anemia complementation group B.
PubMed ID: 15502827
DOI: 10.1038/ng1458
PubMed ID: 16116422
Title: A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M.
PubMed ID: 16116422
DOI: 10.1038/ng1626
PubMed ID: 16916645
Title: UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation.
PubMed ID: 16916645
PubMed ID: 17938197
Title: UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination.
PubMed ID: 17938197
DOI: 10.1128/mcb.00504-07
PubMed ID: 18550849
Title: HES1 is a novel interactor of the Fanconi anemia core complex.
PubMed ID: 18550849
PubMed ID: 19111657
Title: Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI.
PubMed ID: 19111657
PubMed ID: 19589784
Title: FANCI binds branched DNA and is monoubiquitinated by UBE2T-FANCL.
PubMed ID: 19589784
PubMed ID: 22343915
Title: FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway.
PubMed ID: 22343915
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 21775430
Title: Structural analysis of human FANCL, the E3 ligase in the Fanconi anemia pathway.
PubMed ID: 21775430
PubMed ID: 24389026
Title: Structure of the human FANCL RING-Ube2T complex reveals determinants of cognate E3-E2 selection.
PubMed ID: 24389026
Sequence Information:
- Length: 375
- Mass: 42905
- Checksum: E217DF9D64587E5E
- Sequence:
MAVTEASLLR QCPLLLPQNR SKTVYEGFIS AQGRDFHLRI VLPEDLQLKN ARLLCSWQLR TILSGYHRIV QQRMQHSPDL MSFMMELKML LEVALKNRQE LYALPPPPQF YSSLIEEIGT LGWDKLVYAD TCFSTIKLKA EDASGREHLI TLKLKAKYPA ESPDYFVDFP VPFCASWTPQ SSLISIYSQF LAAIESLKAF WDVMDEIDEK TWVLEPEKPP RSATARRIAL GNNVSINIEV DPRHPTMLPE CFFLGADHVV KPLGIKLSRN IHLWDPENSV LQNLKDVLEI DFPARAILEK SDFTMDCGIC YAYQLDGTIP DQVCDNSQCG QPFHQICLYE WLRGLLTSRQ SFNIIFGECP YCSKPITLKM SGRKH
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.