AKIRIN2 | ENSG00000135334 | NCBI 55122

Details for: AKIRIN2

Gene ID: 55122

Symbol: AKIRIN2

Ensembl ID: ENSG00000135334

Description: akirin 2

Associated with

Adaptive immune response
(GO:0002250)
Cerebral cortex development
(GO:0021987)
Chromatin
(GO:0000785)
Cytoplasm
(GO:0005737)
Defense response to bacterium
(GO:0042742)
Embryo development ending in birth or egg hatching
(GO:0009792)
Enzyme binding
(GO:0019899)
Identical protein binding
(GO:0042802)
Innate immune response
(GO:0045087)
Membrane
(GO:0016020)
Negative regulation of gene expression
(GO:0010629)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nuclear protein quality control by the ubiquitin-proteasome system
(GO:0071630)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of adaptive immune response
(GO:0002821)
Positive regulation of b cell activation
(GO:0050871)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of innate immune response
(GO:0045089)
Positive regulation of interleukin-6 production
(GO:0032755)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Proteasome localization
(GO:0031144)
Protein-macromolecule adaptor activity
(GO:0030674)
Protein binding
(GO:0005515)
Protein import into nucleus
(GO:0006606)
Regulation of muscle cell differentiation
(GO:0051147)
Response to lipopolysaccharide
(GO:0032496)
Transcription coregulator activity
(GO:0003712)
Transcription repressor complex
(GO:0017053)

Other Information

Proteins

AKIR2_HUMAN
Q9NW35_HUMAN

Genular Protein ID: 692676763

Symbol: AKIR2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53H80 Q9BQB1

Database IDs:

Citations:

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18066067

Title: Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in Drosophila and mice.

PubMed ID: 18066067

DOI: 10.1038/ni1543

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 34711951

Title: AKIRIN2 controls the nuclear import of proteasomes in vertebrates.

PubMed ID: 34711951

DOI: 10.1038/s41586-021-04035-8

Sequence Information:

Length: 203
Mass: 22496
Checksum: 33AA93AF94DE80A1
Sequence:

MACGATLKRT LDFDPLLSPA SPKRRRCAPL SAPTSAAASP LSAAAATAAS FSAAAASPQK 
YLRMEPSPFG DVSSRLTTEQ ILYNIKQEYK RMQKRRHLET SFQQTDPCCT SDAQPHAFLL 
SGPASPGTSS AASSPLKKEQ PLFTLRQVGM ICERLLKERE EKVREEYEEI LNTKLAEQYD 
AFVKFTHDQI MRRYGEQPAS YVS

Genular Protein ID: 3328709580

Symbol: Q9NW35_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9NW35

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

Length: 135
Mass: 14260
Checksum: 1F84611438042316
Sequence:

MACGATLKRT LDFDPLLSPA SPKRRRCAPL SAPTSAAASP LSAAAATAAS FSAAAASPQK 
YLRMEPSPFG DVSSRLTTEQ ILYNIKQEYK RMQKRRHLET SFQQTDPCCT SDAQPHAFLL 
SGPASPGTSS AASSP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: AKIRIN2

Associated with

Other Information

The DNA sequence and analysis of human chromosome 6. PubMed ID: 14574404

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. PubMed ID: 17081983

Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in Drosophila and mice. PubMed ID: 18066067

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

AKIRIN2 controls the nuclear import of proteasomes in vertebrates. PubMed ID: 34711951

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039