Details for: ELP3

Gene ID: 55140

Symbol: ELP3

Ensembl ID: ENSG00000134014

Description: elongator acetyltransferase complex subunit 3

Associated with

Other Information

Genular Protein ID: 3118879777

Symbol: ELP3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11714725

Title: Purification and characterization of the human elongator complex.

PubMed ID: 11714725

DOI: 10.1074/jbc.m110445200

PubMed ID: 11818576

Title: Human Elongator facilitates RNA polymerase II transcription through chromatin.

PubMed ID: 11818576

DOI: 10.1073/pnas.251672198

PubMed ID: 15902492

Title: The Elp3 subunit of human Elongator complex is functionally similar to its counterpart in yeast.

PubMed ID: 15902492

DOI: 10.1007/s00438-005-1120-2

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 16713582

Title: Transcription impairment and cell migration defects in elongator-depleted cells: implication for familial dysautonomia.

PubMed ID: 16713582

DOI: 10.1016/j.molcel.2006.04.017

PubMed ID: 19185337

Title: Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin.

PubMed ID: 19185337

DOI: 10.1016/j.cell.2008.11.043

PubMed ID: 18996918

Title: Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration.

PubMed ID: 18996918

DOI: 10.1093/hmg/ddn375

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22854966

Title: DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator.

PubMed ID: 22854966

DOI: 10.1074/jbc.m112.402727

PubMed ID: 22002106

Title: Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization.

PubMed ID: 22002106

DOI: 10.1074/mcp.m111.013680

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25960406

Title: The Elp2 subunit is essential for elongator complex assembly and functional regulation.

PubMed ID: 25960406

DOI: 10.1016/j.str.2015.03.018

PubMed ID: 29332244

Title: Structural insights into the function of Elongator.

PubMed ID: 29332244

DOI: 10.1007/s00018-018-2747-6

PubMed ID: 31341009

Title: ELP3 Acetyltransferase is phosphorylated and regulated by the oncogenic anaplastic lymphoma kinase (ALK).

PubMed ID: 31341009

DOI: 10.1042/bcj20190106

PubMed ID: 29415125

Title: Elongator subunit 3 (ELP3) modifies ALS through tRNA modification.

PubMed ID: 29415125

DOI: 10.1093/hmg/ddy043

Sequence Information:

  • Length: 547
  • Mass: 62259
  • Checksum: 60898ADD3DBAD035
  • Sequence:
  • MRQKRKGDLS PAELMMLTIG DVIKQLIEAH EQGKDIDLNK VKTKTAAKYG LSAQPRLVDI 
    IAAVPPQYRK VLMPKLKAKP IRTASGIAVV AVMCKPHRCP HISFTGNICV YCPGGPDSDF 
    EYSTQSYTGY EPTSMRAIRA RYDPFLQTRH RIEQLKQLGH SVDKVEFIVM GGTFMALPEE 
    YRDYFIRNLH DALSGHTSNN IYEAVKYSER SLTKCIGITI ETRPDYCMKR HLSDMLTYGC 
    TRLEIGVQSV YEDVARDTNR GHTVKAVCES FHLAKDSGFK VVAHMMPDLP NVGLERDIEQ 
    FTEFFENPAF RPDGLKLYPT LVIRGTGLYE LWKSGRYKSY SPSDLVELVA RILALVPPWT 
    RVYRVQRDIP MPLVSSGVEH GNLRELALAR MKDLGIQCRD VRTREVGIQE IHHKVRPYQV 
    ELVRRDYVAN GGWETFLSYE DPDQDILIGL LRLRKCSEET FRFELGGGVS IVRELHVYGS 
    VVPVSSRDPT KFQHQGFGML LMEEAERIAR EEHGSGKIAV ISGVGTRNYY RKIGYRLQGP 
    YMVKMLK

Genular Protein ID: 2014016381

Symbol: B4DKA4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

Sequence Information:

  • Length: 475
  • Mass: 54234
  • Checksum: C22D89A974C79E7F
  • Sequence:
  • MPKLKAKPIR TASGIAVVAV MCKPHRCPHI SFTGNICVYC PGGPDSDFEY STQSYTGYEP 
    TSMRAIRARY DPFLQTRHRI EQLKQLGHSV DKVEFIVMGG TFMALPEEYR DYFIRNLHDA 
    LSGHTSNNIY EAVKYSERSL TKCIGITIET RPDYCMKRHL SDMLTYGCTR LEIGVQSVYE 
    DVARDTNRGH TVKAVCESFH LAKDSGFKVV AHMMPDLPNV GLERDIEQFT EFFENPAFRP 
    DGLKLYPTLV IRGTGLYELW KSGRYKSYSP SDLVELVARI LALVPPWTRV YRVQRDIPMP 
    LVSSGVEHGN LRELALARMK DLGIQCRDVR TREVGIQEIH HKVRPYQVEL VRRDYVANGG 
    WETFLSYEDP DQDILIGLLR LRKCSEETFR FELGGGVSIV RELHVYGSVV PVSSRDPTKF 
    QHQGFGMLLM EEAERIAREE HGSGKIAVIS GVGTRNYYRK IGYRLQGPYM VKMLK

Genular Protein ID: 1230675850

Symbol: B4DXV1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 418
  • Mass: 48062
  • Checksum: B4B61C3DB5550CCE
  • Sequence:
  • MCPTSMRAIR ARYDPFLQTR HRIEQLKQLG HSVDKVEFIV MGGTFMALPE EYRDYFIRNL 
    HDALSGHTSN NIYEAVKYSE RSLTKCIGIT IETRPDYCMK RHLSDMLTYG CTRLEIGVQS 
    VYEDVARDTN RGHTVKAVCE SFHLAKDSGF KVVAHMMPDL PNVGLERDIE QFTEFFENPA 
    FRPDGLKLYP TLVIRGTGLY ELWKSGRYKS YSPSDLVELV ARILALVPPW TRVYRVQRDI 
    PMPLVSSGVE HGNLRELALA RMKDLGIQCR DVRTREVGIQ EIHHKVRPYQ VELVRRDYVA 
    NGGWETFLSY EDPDQDILIG LLRLRKCSEE TFRFELGGGV SIVRELHVYG SVVPVSSRDP 
    TKFQHQGFGM LLMEEAERIA REEHGSGKIA VISGVGTRNY YRKIGYRLQG PYMVKMLK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.