AVPR1A | ENSG00000166148 | NCBI 552

Details for: AVPR1A

Gene ID: 552

Symbol: AVPR1A

Ensembl ID: ENSG00000166148

Description: arginine vasopressin receptor 1A

Associated with

Class a/1 (rhodopsin-like receptors)
(R-HSA-373076)
Defective avp does not bind avpr1a,b and causes neurohypophyseal diabetes insipidus (ndi)
(R-HSA-5619099)
Disease
(R-HSA-1643685)
Disorders of transmembrane transporters
(R-HSA-5619115)
G alpha (q) signalling events
(R-HSA-416476)
Gpcr downstream signalling
(R-HSA-388396)
Gpcr ligand binding
(R-HSA-500792)
Peptide ligand-binding receptors
(R-HSA-375276)
Signaling by gpcr
(R-HSA-372790)
Signal transduction
(R-HSA-162582)
Slc transporter disorders
(R-HSA-5619102)
Vasopressin-like receptors
(R-HSA-388479)
Activation of phospholipase c activity
(GO:0007202)
Blood circulation
(GO:0008015)
Calcium-mediated signaling
(GO:0019722)
Cellular response to hormone stimulus
(GO:0032870)
Cellular response to water deprivation
(GO:0042631)
Endocytic vesicle
(GO:0030139)
Endosome
(GO:0005768)
Generation of precursor metabolites and energy
(GO:0006091)
G protein-coupled receptor signaling pathway
(GO:0007186)
Grooming behavior
(GO:0007625)
Maternal aggressive behavior
(GO:0002125)
Maternal behavior
(GO:0042711)
Myotube differentiation
(GO:0014902)
Negative regulation of female receptivity
(GO:0007621)
Negative regulation of transmission of nerve impulse
(GO:0051970)
Peptide binding
(GO:0042277)
Peptide hormone binding
(GO:0017046)
Plasma membrane
(GO:0005886)
Positive regulation of cell growth
(GO:0030307)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cellular ph reduction
(GO:0032849)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of glutamate secretion
(GO:0014049)
Positive regulation of heart rate
(GO:0010460)
Positive regulation of prostaglandin biosynthetic process
(GO:0031394)
Positive regulation of systemic arterial blood pressure
(GO:0003084)
Positive regulation of vasoconstriction
(GO:0045907)
Protein binding
(GO:0005515)
Protein kinase c binding
(GO:0005080)
Regulation of systemic arterial blood pressure by vasopressin
(GO:0001992)
Response to corticosterone
(GO:0051412)
Social behavior
(GO:0035176)
Sperm ejaculation
(GO:0042713)
Telencephalon development
(GO:0021537)
Transport across blood-brain barrier
(GO:0150104)
V1a vasopressin receptor binding
(GO:0031894)
Vasopressin receptor activity
(GO:0005000)

Other Information

Proteins

Vasopressin V1a receptor

Genular Protein ID: 2646177688

Symbol: V1AR_HUMAN

Name: Vasopressin V1a receptor

UniProtKB Accession Codes:

P37288

Database IDs:

Citations:

PubMed ID: 8106369

Title: Molecular cloning, sequencing, and functional expression of a cDNA encoding the human V1a vasopressin receptor.

PubMed ID: 8106369

DOI: 10.1016/s0021-9258(17)41863-1

PubMed ID: 8074728

Title: Cloning, functional expression and tissue distribution of human cDNA for the vascular-type vasopressin receptor.

PubMed ID: 8074728

DOI: 10.1006/bbrc.1994.2150

PubMed ID: 9357056

Title: Functional vasopressin V1 type receptors are present in variant as well as classical forms of small-cell carcinoma.

PubMed ID: 9357056

DOI: 10.1016/s0196-9781(97)00072-7

PubMed ID: 9581826

Title: Expression of all known vasopressin receptor subtypes by small cell tumors implies a multifaceted role for this neuropeptide.

PubMed ID: 9581826

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12082568

Title: Transmission disequilibrium testing of arginine vasopressin receptor 1A (AVPR1A) polymorphisms in autism.

PubMed ID: 12082568

DOI: 10.1038/sj.mp.4001125

PubMed ID: 16511036

Title: A C-terminal segment of the V1R vasopressin receptor is unstructured in the crystal structure of its chimera with the maltose-binding protein.

PubMed ID: 16511036

DOI: 10.1107/s1744309105007293

Sequence Information:

Length: 418
Mass: 46800
Checksum: 477D4260EC826561
Sequence:

MRLSAGPDAG PSGNSSPWWP LATGAGNTSR EAEALGEGNG PPRDVRNEEL AKLEIAVLAV 
TFAVAVLGNS SVLLALHRTP RKTSRMHLFI RHLSLADLAV AFFQVLPQMC WDITYRFRGP 
DWLCRVVKHL QVFGMFASAY MLVVMTADRY IAVCHPLKTL QQPARRSRLM IAAAWVLSFV 
LSTPQYFVFS MIEVNNVTKA RDCWATFIQP WGSRAYVTWM TGGIFVAPVV ILGTCYGFIC 
YNIWCNVRGK TASRQSKGAE QAGVAFQKGF LLAPCVSSVK SISRAKIRTV KMTFVIVTAY 
IVCWAPFFII QMWSVWDPMS VWTESENPTI TITALLGSLN SCCNPWIYMF FSGHLLQDCV 
QSFPCCQNMK EKFNKEDTDS MSRRQTFYSN NRSPTNSTGM WKDSPKSSKS IKFIPVST

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: AVPR1A

Associated with

Other Information

Molecular cloning, sequencing, and functional expression of a cDNA encoding the human V1a vasopressin receptor. PubMed ID: 8106369

Cloning, functional expression and tissue distribution of human cDNA for the vascular-type vasopressin receptor. PubMed ID: 8074728

Functional vasopressin V1 type receptors are present in variant as well as classical forms of small-cell carcinoma. PubMed ID: 9357056

Expression of all known vasopressin receptor subtypes by small cell tumors implies a multifaceted role for this neuropeptide. PubMed ID: 9581826

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Transmission disequilibrium testing of arginine vasopressin receptor 1A (AVPR1A) polymorphisms in autism. PubMed ID: 12082568

A C-terminal segment of the V1R vasopressin receptor is unstructured in the crystal structure of its chimera with the maltose-binding protein. PubMed ID: 16511036