Details for: ARL8B

Gene ID: 55207

Symbol: ARL8B

Ensembl ID: ENSG00000134108

Description: ADP ribosylation factor like GTPase 8B

Associated with

Other Information

Genular Protein ID: 455763599

Symbol: ARL8B_HUMAN

Name: ADP-ribosylation factor-like protein 10C

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15331635

Title: Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation.

PubMed ID: 15331635

DOI: 10.1242/jcs.01347

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16650381

Title: The Arf-family protein, Arl8b, is involved in the spatial distribution of lysosomes.

PubMed ID: 16650381

DOI: 10.1016/j.bbrc.2006.03.221

PubMed ID: 16537643

Title: An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility.

PubMed ID: 16537643

DOI: 10.1242/jcs.02958

PubMed ID: 17897319

Title: Integral and associated lysosomal membrane proteins.

PubMed ID: 17897319

DOI: 10.1111/j.1600-0854.2007.00643.x

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22172677

Title: Arl8 and SKIP act together to link lysosomes to kinesin-1.

PubMed ID: 22172677

DOI: 10.1016/j.devcel.2011.10.007

PubMed ID: 21802320

Title: Lysosomal trafficking, antigen presentation, and microbial killing are controlled by the Arf-like GTPase Arl8b.

PubMed ID: 21802320

DOI: 10.1016/j.immuni.2011.06.009

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24088571

Title: Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell-mediated cytotoxicity.

PubMed ID: 24088571

DOI: 10.1091/mbc.e13-05-0259

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25898167

Title: BORC, a multisubunit complex that regulates lysosome positioning.

PubMed ID: 25898167

DOI: 10.1016/j.devcel.2015.02.011

PubMed ID: 25908847

Title: The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes.

PubMed ID: 25908847

DOI: 10.1242/jcs.162651

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27808481

Title: RNF167 targets Arl8B for degradation to regulate lysosome positioning and endocytic trafficking.

PubMed ID: 27808481

DOI: 10.1111/febs.13947

PubMed ID: 28325809

Title: The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes.

PubMed ID: 28325809

DOI: 10.1083/jcb.201607085

PubMed ID: 29592961

Title: Lysosome-Mediated Plasma Membrane Repair Is Dependent on the Small GTPase Arl8b and Determines Cell Death Type in Mycobacterium tuberculosis Infection.

PubMed ID: 29592961

DOI: 10.4049/jimmunol.1700829

PubMed ID: 33157038

Title: beta-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway.

PubMed ID: 33157038

DOI: 10.1016/j.cell.2020.10.039

Sequence Information:

  • Length: 186
  • Mass: 21539
  • Checksum: 5030B01AFD749223
  • Sequence:
  • MLALISRLLD WFRSLFWKEE MELTLVGLQY SGKTTFVNVI ASGQFSEDMI PTVGFNMRKV 
    TKGNVTIKIW DIGGQPRFRS MWERYCRGVN AIVYMIDAAD REKIEASRNE LHNLLDKPQL 
    QGIPVLVLGN KRDLPNALDE KQLIEKMNLS AIQDREICCY SISCKEKDNI DITLQWLIQH 
    SKSRRS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.