Details for: ATAD3A

Gene ID: 55210

Symbol: ATAD3A

Ensembl ID: ENSG00000197785

Description: ATPase family AAA domain containing 3A

Associated with

Other Information

Genular Protein ID: 2210413716

Symbol: ATD3A_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 20332122

Title: ATPase family AAA domain-containing 3A is a novel anti-apoptotic factor in lung adenocarcinoma cells.

PubMed ID: 20332122

DOI: 10.1242/jcs.062034

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17210950

Title: The AAA+ protein ATAD3 has displacement loop binding properties and is involved in mitochondrial nucleoid organization.

PubMed ID: 17210950

DOI: 10.1083/jcb.200609158

PubMed ID: 18063578

Title: The layered structure of human mitochondrial DNA nucleoids.

PubMed ID: 18063578

DOI: 10.1074/jbc.m708444200

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20349121

Title: Topological analysis of ATAD3A insertion in purified human mitochondria.

PubMed ID: 20349121

DOI: 10.1007/s10863-010-9269-8

PubMed ID: 20154147

Title: The AAA+ ATPase ATAD3A controls mitochondrial dynamics at the interface of the inner and outer membranes.

PubMed ID: 20154147

DOI: 10.1128/mcb.00007-10

PubMed ID: 20351179

Title: The calcium-dependent interaction between S100B and the mitochondrial AAA ATPase ATAD3A and the role of this complex in the cytoplasmic processing of ATAD3A.

PubMed ID: 20351179

DOI: 10.1128/mcb.01468-09

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22664726

Title: ATAD3B is a human embryonic stem cell specific mitochondrial protein, re-expressed in cancer cells, that functions as dominant negative for the ubiquitous ATAD3A.

PubMed ID: 22664726

DOI: 10.1016/j.mito.2012.05.005

PubMed ID: 22453275

Title: Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis.

PubMed ID: 22453275

DOI: 10.1093/nar/gks266

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 31522117

Title: Structural Basis of Mitochondrial Scaffolds by Prohibitin Complexes: Insight into a Role of the Coiled-Coil Region.

PubMed ID: 31522117

DOI: 10.1016/j.isci.2019.08.056

PubMed ID: 27640307

Title: Recurrent de novo and biallelic variation of ATAD3A, encoding a mitochondrial membrane protein, Results in distinct neurological syndromes.

PubMed ID: 27640307

DOI: 10.1016/j.ajhg.2016.08.007

PubMed ID: 29053797

Title: Genotype-phenotype correlation in ATAD3A deletions: not just of scientific relevance.

PubMed ID: 29053797

DOI: 10.1093/brain/awx239

PubMed ID: 31727539

Title: Novel ATAD3A recessive mutation associated to fatal cerebellar hypoplasia with multiorgan involvement and mitochondrial structural abnormalities.

PubMed ID: 31727539

DOI: 10.1016/j.ymgme.2019.10.012

Sequence Information:

  • Length: 634
  • Mass: 71369
  • Checksum: 47E765629B6F3267
  • Sequence:
  • MSWLFGINKG PKGEGAGPPP PLPPAQPGAE GGGDRGLGDR PAPKDKWSNF DPTGLERAAK 
    AARELEHSRY AKDALNLAQM QEQTLQLEQQ SKLKMRLEAL SLLHTLVWAW SLCRAGAVQT 
    QERLSGSASP EQVPAGECCA LQEYEAAVEQ LKSEQIRAQA EERRKTLSEE TRQHQARAQY 
    QDKLARQRYE DQLKQQQLLN EENLRKQEES VQKQEAMRRA TVEREMELRH KNEMLRVEAE 
    ARARAKAERE NADIIREQIR LKAAEHRQTV LESIRTAGTL FGEGFRAFVT DWDKVTATVA 
    GLTLLAVGVY SAKNATLVAG RFIEARLGKP SLVRETSRIT VLEALRHPIQ VSRRLLSRPQ 
    DALEGVVLSP SLEARVRDIA IATRNTKKNR SLYRNILMYG PPGTGKTLFA KKLALHSGMD 
    YAIMTGGDVA PMGREGVTAM HKLFDWANTS RRGLLLFVDE ADAFLRKRAT EKISEDLRAT 
    LNAFLYRTGQ HSNKFMLVLA SNQPEQFDWA INDRINEMVH FDLPGQEERE RLVRMYFDKY 
    VLKPATEGKQ RLKLAQFDYG RKCSEVARLT EGMSGREIAQ LAVSWQATAY ASEDGVLTEA 
    MMDTRVQDAV QQHQQKMCWL KAEGPGRGDE PSPS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.