Details for: STEAP3

Gene ID: 55240

Symbol: STEAP3

Ensembl ID: ENSG00000115107

Description: STEAP3 metalloreductase

Associated with

Other Information

Genular Protein ID: 1720760037

Symbol: STEA3_HUMAN

Name: Metalloreductase STEAP3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12606722

Title: The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase.

PubMed ID: 12606722

DOI: 10.1073/pnas.0530298100

PubMed ID: 15897894

Title: Molecular cloning and characterization of STAMP2, an androgen-regulated six transmembrane protein that is overexpressed in prostate cancer.

PubMed ID: 15897894

DOI: 10.1038/sj.onc.1208677

PubMed ID: 10969787

Title: Growth inhibition of prostate cancer by an adenovirus expressing a novel tumor suppressor gene, pHyde.

PubMed ID: 10969787

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12866033

Title: Human pHyde is not a classical tumor suppressor gene in prostate cancer.

PubMed ID: 12866033

DOI: 10.1002/ijc.11278

PubMed ID: 15319436

Title: TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway.

PubMed ID: 15319436

DOI: 10.1074/jbc.m404850200

PubMed ID: 15885357

Title: Global gene repression in hepatocellular carcinoma and fetal liver, and suppression of dudulin-2 mRNA as a possible marker for the cirrhosis-to-tumor transition.

PubMed ID: 15885357

DOI: 10.1016/j.jhep.2005.01.027

PubMed ID: 16227996

Title: Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells.

PubMed ID: 16227996

DOI: 10.1038/ng1658

PubMed ID: 16651434

Title: The regulation of exosome secretion: a novel function of the p53 protein.

PubMed ID: 16651434

DOI: 10.1158/0008-5472.can-05-4579

PubMed ID: 22031863

Title: A novel type of congenital hypochromic anemia associated with a nonsense mutation in the STEAP3/TSAP6 gene.

PubMed ID: 22031863

DOI: 10.1182/blood-2011-01-329011

PubMed ID: 22624035

Title: Exosome-related multi-pass transmembrane protein TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysis.

PubMed ID: 22624035

DOI: 10.1371/journal.pone.0037452

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26205815

Title: Characterization of a single b-type heme, FAD, and metal binding sites in the transmembrane domain of six-transmembrane epithelial antigen of the prostate (STEAP) family proteins.

PubMed ID: 26205815

DOI: 10.1074/jbc.m115.664565

PubMed ID: 18495927

Title: Structure of the membrane proximal oxidoreductase domain of human Steap3, the dominant ferrireductase of the erythroid transferrin cycle.

PubMed ID: 18495927

DOI: 10.1073/pnas.0801318105

Sequence Information:

  • Length: 488
  • Mass: 54601
  • Checksum: C89EB0D0430F9BFB
  • Sequence:
  • MPEEMDKPLI SLHLVDSDSS LAKVPDEAPK VGILGSGDFA RSLATRLVGS GFKVVVGSRN 
    PKRTARLFPS AAQVTFQEEA VSSPEVIFVA VFREHYSSLC SLSDQLAGKI LVDVSNPTEQ 
    EHLQHRESNA EYLASLFPTC TVVKAFNVIS AWTLQAGPRD GNRQVPICGD QPEAKRAVSE 
    MALAMGFMPV DMGSLASAWE VEAMPLRLLP AWKVPTLLAL GLFVCFYAYN FVRDVLQPYV 
    QESQNKFFKL PVSVVNTTLP CVAYVLLSLV YLPGVLAAAL QLRRGTKYQR FPDWLDHWLQ 
    HRKQIGLLSF FCAALHALYS FCLPLRRAHR YDLVNLAVKQ VLANKSHLWV EEEVWRMEIY 
    LSLGVLALGT LSLLAVTSLP SIANSLNWRE FSFVQSSLGF VALVLSTLHT LTYGWTRAFE 
    ESRYKFYLPP TFTLTLLVPC VVILAKALFL LPCISRRLAR IRRGWEREST IKFTLPTDHA 
    LAEKTSHV

Genular Protein ID: 3952780306

Symbol: B8ZZX6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 457
  • Mass: 50628
  • Checksum: 443AA3831B991D62
  • Sequence:
  • MPEEMDKPLI SLHLVDSDSS LAKVPDEAPK VGILGSGDFA RSLATRLVGS GFKVVVGSRN 
    PKRTARLFPS AAQVTFQEEA VSSPEVIFVA VFREHYSSLC SLSDQLAGKI LVDVSNPTEQ 
    EHLQHRESNA EYLASLFPTC TVVKAFNVIS AWTLQAGPRD GNRQVPICGD QPEAKRAVSE 
    MALAMGFMPV DMGSLASAWE VEAMPLRLLP AWKVPTLLAL GLFVCFYAYN FVRDVLQPYV 
    QESQNKFFKL PVSVVNTTLP CVAYVLLSLV YLPGVLAAAL QLRRGTKYQR FPDWLDHWLQ 
    HRKQIGLLSF FCAALHALYS FCLPLRRAHR YDLVNLAVKQ VLANKSHLWV EEEVWRMEIY 
    LSLGVLALGT LSLLAVTSLP SIANSLNWRE FSFVQCVATS SAGNTGSGTR RPESQSQDPH 
    LPAPHHQTSF LGPRSFCCSL VPVSTPYGHQ EDLSWTR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.