Details for: BRF2

Gene ID: 55290

Symbol: BRF2

Ensembl ID: ENSG00000104221

Description: BRF2 RNA polymerase III transcription initiation factor subunit

Associated with

Other Information

Genular Protein ID: 1863463732

Symbol: BRF2_HUMAN

Name: Transcription factor IIIB 50 kDa subunit

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11040218

Title: Different human TFIIIB activities direct RNA polymerase III transcription from TATA-containing and TATA-less promoters.

PubMed ID: 11040218

DOI: 10.1101/gad.836400

PubMed ID: 11121026

Title: A stable complex of a novel transcription factor IIB- related factor, human TFIIIB50, and associated proteins mediate selective transcription by RNA polymerase III of genes with upstream promoter elements.

PubMed ID: 11121026

DOI: 10.1073/pnas.97.26.14200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11483580

Title: Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs.

PubMed ID: 11483580

DOI: 10.1101/gr.175501

PubMed ID: 11564744

Title: BRFU, a TFIIB-like factor, is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interaction with TATA-binding protein.

PubMed ID: 11564744

DOI: 10.1074/jbc.m108515200

PubMed ID: 12016223

Title: Assembly of human small nuclear RNA gene-specific transcription factor IIIB complex de novo on and off promoter.

PubMed ID: 12016223

DOI: 10.1074/jbc.m203119200

PubMed ID: 12391172

Title: Redundant cooperative interactions for assembly of a human U6 transcription initiation complex.

PubMed ID: 12391172

DOI: 10.1128/mcb.22.22.8067-8078.2002

PubMed ID: 12621023

Title: The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition.

PubMed ID: 12621023

DOI: 10.1074/jbc.m204247200

PubMed ID: 14527415

Title: A minimal RNA polymerase III transcription system from human cells reveals positive and negative regulatory roles for CK2.

PubMed ID: 14527415

DOI: 10.1016/j.molcel.2003.08.011

PubMed ID: 16227591

Title: Structure-function analysis of the human TFIIB-related factor II protein reveals an essential role for the C-terminal domain in RNA polymerase III transcription.

PubMed ID: 16227591

DOI: 10.1128/mcb.25.21.9406-9418.2005

PubMed ID: 16769183

Title: A role for Yin Yang-1 (YY1) in the assembly of snRNA transcription complexes.

PubMed ID: 16769183

DOI: 10.1016/j.gene.2006.03.012

PubMed ID: 17505538

Title: Human Maf1 negatively regulates RNA polymerase III transcription via the TFIIB family members Brf1 and Brf2.

PubMed ID: 17505538

DOI: 10.7150/ijbs.3.292

PubMed ID: 17624304

Title: The green tea component EGCG inhibits RNA polymerase III transcription.

PubMed ID: 17624304

DOI: 10.1016/j.bbrc.2007.06.114

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26638071

Title: Redox signaling by the RNA polymerase III TFIIB-related factor Brf2.

PubMed ID: 26638071

DOI: 10.1016/j.cell.2015.11.005

Sequence Information:

  • Length: 419
  • Mass: 46533
  • Checksum: 90A39F72DBA14888
  • Sequence:
  • MPGRGRCPDC GSTELVEDSH YSQSQLVCSD CGCVVTEGVL TTTFSDEGNL REVTYSRSTG 
    ENEQVSRSQQ RGLRRVRDLC RVLQLPPTFE DTAVAYYQQA YRHSGIRAAR LQKKEVLVGC 
    CVLITCRQHN WPLTMGAICT LLYADLDVFS STYMQIVKLL GLDVPSLCLA ELVKTYCSSF 
    KLFQASPSVP AKYVEDKEKM LSRTMQLVEL ANETWLVTGR HPLPVITAAT FLAWQSLQPA 
    DRLSCSLARF CKLANVDLPY PASSRLQELL AVLLRMAEQL AWLRVLRLDK RSVVKHIGDL 
    LQHRQSLVRS AFRDGTAEVE TREKEPPGWG QGQGEGEVGN NSLGLPQGKR PASPALLLPP 
    CMLKSPKRIC PVPPVSTVTG DENISDSEIE QYLRTPQEVR DFQRAQAARQ AATSVPNPP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.