AVPR1B | ENSG00000198049 | NCBI 553

Details for: AVPR1B

Gene ID: 553

Symbol: AVPR1B

Ensembl ID: ENSG00000198049

Description: arginine vasopressin receptor 1B

Associated with

Class a/1 (rhodopsin-like receptors)
(R-HSA-373076)
Defective avp does not bind avpr1a,b and causes neurohypophyseal diabetes insipidus (ndi)
(R-HSA-5619099)
Disease
(R-HSA-1643685)
Disorders of transmembrane transporters
(R-HSA-5619115)
G alpha (q) signalling events
(R-HSA-416476)
Gpcr downstream signalling
(R-HSA-388396)
Gpcr ligand binding
(R-HSA-500792)
Peptide ligand-binding receptors
(R-HSA-375276)
Signaling by gpcr
(R-HSA-372790)
Signal transduction
(R-HSA-162582)
Slc transporter disorders
(R-HSA-5619102)
Vasopressin-like receptors
(R-HSA-388479)
Activation of phospholipase c activity
(GO:0007202)
Cellular response to hormone stimulus
(GO:0032870)
Endosome
(GO:0005768)
Golgi apparatus
(GO:0005794)
G protein-coupled receptor signaling pathway
(GO:0007186)
Peptide binding
(GO:0042277)
Plasma membrane
(GO:0005886)
Positive regulation of arachidonic acid secretion
(GO:0090238)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of inositol phosphate biosynthetic process
(GO:0060732)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of phospholipase a2 activity
(GO:0032430)
Positive regulation of vasoconstriction
(GO:0045907)
Protein kinase c binding
(GO:0005080)
Regulation of cell population proliferation
(GO:0042127)
Regulation of systemic arterial blood pressure by vasopressin
(GO:0001992)
Symbiont entry into host cell
(GO:0046718)
Transport across blood-brain barrier
(GO:0150104)
Vasopressin receptor activity
(GO:0005000)

Other Information

Proteins

AVPR V1b

Genular Protein ID: 75267635

Symbol: V1BR_HUMAN

Name: AVPR V1b

UniProtKB Accession Codes:

P47901 B0M0J6 Q5TZ00

Database IDs:

Citations:

PubMed ID: 7929452

Title: Molecular cloning and functional expression of a cDNA encoding the human V1b vasopressin receptor.

PubMed ID: 7929452

DOI: 10.1016/s0021-9258(18)47129-3

PubMed ID: 7805841

Title: Cloning and characterization of the human V3 pituitary vasopressin receptor.

PubMed ID: 7805841

DOI: 10.1016/0014-5793(94)01268-7

PubMed ID: 9357056

Title: Functional vasopressin V1 type receptors are present in variant as well as classical forms of small-cell carcinoma.

PubMed ID: 9357056

DOI: 10.1016/s0196-9781(97)00072-7

PubMed ID: 9581826

Title: Expression of all known vasopressin receptor subtypes by small cell tumors implies a multifaceted role for this neuropeptide.

PubMed ID: 9581826

PubMed ID: 10607899

Title: Nucleotide sequence and structural organization of the human vasopressin pituitary receptor (V3) gene.

PubMed ID: 10607899

DOI: 10.1016/s0378-1119(99)00468-0

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 33713620

Title: Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system.

PubMed ID: 33713620

DOI: 10.1016/j.cell.2021.02.053

PubMed ID: 17909131

Title: Evidence of an association between the vasopressin V1b receptor gene (AVPR1B) and childhood-onset mood disorders.

PubMed ID: 17909131

DOI: 10.1001/archpsyc.64.10.1189

Sequence Information:

Length: 424
Mass: 46971
Checksum: 35190281D3EDB6A7
Sequence:

MDSGPLWDAN PTPRGTLSAP NATTPWLGRD EELAKVEIGV LATVLVLATG GNLAVLLTLG 
QLGRKRSRMH LFVLHLALTD LAVALFQVLP QLLWDITYRF QGPDLLCRAV KYLQVLSMFA 
STYMLLAMTL DRYLAVCHPL RSLQQPGQST YLLIAAPWLL AAIFSLPQVF IFSLREVIQG 
SGVLDCWADF GFPWGPRAYL TWTTLAIFVL PVTMLTACYS LICHEICKNL KVKTQAWRVG 
GGGWRTWDRP SPSTLAATTR GLPSRVSSIN TISRAKIRTV KMTFVIVLAY IACWAPFFSV 
QMWSVWDKNA PDEDSTNVAF TISMLLGNLN SCCNPWIYMG FNSHLLPRPL RHLACCGGPQ 
PRMRRRLSDG SLSSRHTTLL TRSSCPATLS LSLSLTLSGR PRPEESPRDL ELADGEGTAE 
TIIF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: AVPR1B

Associated with

Other Information

Molecular cloning and functional expression of a cDNA encoding the human V1b vasopressin receptor. PubMed ID: 7929452

Cloning and characterization of the human V3 pituitary vasopressin receptor. PubMed ID: 7805841

Functional vasopressin V1 type receptors are present in variant as well as classical forms of small-cell carcinoma. PubMed ID: 9357056

Expression of all known vasopressin receptor subtypes by small cell tumors implies a multifaceted role for this neuropeptide. PubMed ID: 9581826

Nucleotide sequence and structural organization of the human vasopressin pituitary receptor (V3) gene. PubMed ID: 10607899

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system. PubMed ID: 33713620

Evidence of an association between the vasopressin V1b receptor gene (AVPR1B) and childhood-onset mood disorders. PubMed ID: 17909131