Details for: SLC29A3

Gene ID: 55315

Symbol: SLC29A3

Ensembl ID: ENSG00000198246

Description: solute carrier family 29 member 3

Associated with

Other Information

Genular Protein ID: 3997482896

Symbol: S29A3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11396612

Title: The ENT family of eukaryote nucleoside and nucleobase transporters: recent advances in the investigation of structure/function relationships and the identification of novel isoforms.

PubMed ID: 11396612

DOI: 10.1080/09687680118799

PubMed ID: 12384580

Title: Comparative genomic analysis of equilibrative nucleoside transporters suggests conserved protein structure despite limited sequence identity.

PubMed ID: 12384580

DOI: 10.1093/nar/gkf564

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15701636

Title: Functional characterization of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes.

PubMed ID: 15701636

DOI: 10.1074/jbc.m414337200

PubMed ID: 17897319

Title: Integral and associated lysosomal membrane proteins.

PubMed ID: 17897319

DOI: 10.1111/j.1600-0854.2007.00643.x

PubMed ID: 19164483

Title: Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3.

PubMed ID: 19164483

DOI: 10.1152/ajpgi.90672.2008

PubMed ID: 20595384

Title: Human equilibrative nucleoside transporter-3 (hENT3) spectrum disorder mutations impair nucleoside transport, protein localization, and stability.

PubMed ID: 20595384

DOI: 10.1074/jbc.m110.109199

PubMed ID: 22174130

Title: Equilibrative nucleoside transporter 3 deficiency perturbs lysosome function and macrophage homeostasis.

PubMed ID: 22174130

DOI: 10.1126/science.1213682

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28729424

Title: Molecular determinants of acidic pH-dependent transport of human equilibrative nucleoside transporter 3.

PubMed ID: 28729424

DOI: 10.1074/jbc.m117.787952

PubMed ID: 18940313

Title: The H syndrome is caused by mutations in the nucleoside transporter hENT3.

PubMed ID: 18940313

DOI: 10.1016/j.ajhg.2008.09.013

PubMed ID: 19336477

Title: SLC29A3 gene is mutated in pigmented hypertrichosis with insulin-dependent diabetes mellitus syndrome and interacts with the insulin signaling pathway.

PubMed ID: 19336477

DOI: 10.1093/hmg/ddp161

PubMed ID: 20199539

Title: H syndrome: novel and recurrent mutations in SLC29A3.

PubMed ID: 20199539

DOI: 10.1111/j.1365-2133.2010.09653.x

PubMed ID: 20619369

Title: Expanding the clinical spectrum of SLC29A3 gene defects.

PubMed ID: 20619369

DOI: 10.1016/j.ejmg.2010.06.012

PubMed ID: 20399510

Title: Early-onset sensorineural hearing loss is a prominent feature of H syndrome.

PubMed ID: 20399510

DOI: 10.1016/j.ijporl.2010.03.053

PubMed ID: 19889517

Title: The H syndrome: two novel mutations affecting the same amino acid residue of hENT3.

PubMed ID: 19889517

DOI: 10.1016/j.jdermsci.2009.09.011

PubMed ID: 20140240

Title: Mutations in SLC29A3, encoding an equilibrative nucleoside transporter ENT3, cause a familial histiocytosis syndrome (Faisalabad histiocytosis) and familial Rosai-Dorfman disease.

PubMed ID: 20140240

DOI: 10.1371/journal.pgen.1000833

PubMed ID: 21888995

Title: Progressive hearing loss associated with a unique cervical node due to a homozygous SLC29A3 mutation: a very mild phenotype.

PubMed ID: 21888995

DOI: 10.1016/j.ejmg.2011.06.009

Sequence Information:

  • Length: 475
  • Mass: 51815
  • Checksum: DBF0918ECA6D5A70
  • Sequence:
  • MAVVSEDDFQ HSSNSTYRTT SSSLRADQEA LLEKLLDRPP PGLQRPEDRF CGTYIIFFSL 
    GIGSLLPWNF FITAKEYWMF KLRNSSSPAT GEDPEGSDIL NYFESYLAVA STVPSMLCLV 
    ANFLLVNRVA VHIRVLASLT VILAIFMVIT ALVKVDTSSW TRGFFAVTIV CMVILSGAST 
    VFSSSIYGMT GSFPMRNSQA LISGGAMGGT VSAVASLVDL AASSDVRNSA LAFFLTATVF 
    LVLCMGLYLL LSRLEYARYY MRPVLAAHVF SGEEELPQDS LSAPSVASRF IDSHTPPLRP 
    ILKKTASLGF CVTYVFFITS LIYPAICTNI ESLNKGSGSL WTTKFFIPLT TFLLYNFADL 
    CGRQLTAWIQ VPGPNSKALP GFVLLRTCLI PLFVLCNYQP RVHLKTVVFQ SDVYPALLSS 
    LLGLSNGYLS TLALLYGPKI VPRELAEATG VVMSFYVCLG LTLGSACSTL LVHLI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.