Details for: ACER3

Gene ID: 55331

Symbol: ACER3

Ensembl ID: ENSG00000078124

Description: alkaline ceramidase 3

Associated with

Other Information

Genular Protein ID: 890579342

Symbol: ACER3_HUMAN

Name: Alkaline ceramidase 3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11356846

Title: Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide.

PubMed ID: 11356846

DOI: 10.1074/jbc.m102818200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 20207939

Title: Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes.

PubMed ID: 20207939

DOI: 10.1096/fj.09-153635

PubMed ID: 20068046

Title: Alkaline ceramidase 3 (ACER3) hydrolyzes unsaturated long-chain ceramides, and its down-regulation inhibits both cell proliferation and apoptosis.

PubMed ID: 20068046

DOI: 10.1074/jbc.m109.063586

PubMed ID: 26792856

Title: Deficiency of the alkaline ceramidase ACER3 manifests in early childhood by progressive leukodystrophy.

PubMed ID: 26792856

DOI: 10.1136/jmedgenet-2015-103457

PubMed ID: 30575723

Title: Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy.

PubMed ID: 30575723

DOI: 10.1038/s41467-018-07864-w

Sequence Information:

  • Length: 267
  • Mass: 31552
  • Checksum: CFD2A901F12A5918
  • Sequence:
  • MAPAADREGY WGPTTSTLDW CEENYSVTWY IAEFWNTVSN LIMIIPPMFG AVQSVRDGLE 
    KRYIASYLAL TVVGMGSWCF HMTLKYEMQL LDELPMIYSC CIFVYCMFEC FKIKNSVNYH 
    LLFTLVLFSL IVTTVYLKVK EPIFHQVMYG MLVFTLVLRS IYIVTWVYPW LRGLGYTSLG 
    IFLLGFLFWN IDNIFCESLR NFRKKVPPII GITTQFHAWW HILTGLGSYL HILFSLYTRT 
    LYLRYRPKVK FLFGIWPVIL FEPLRKH

Genular Protein ID: 2173601563

Symbol: B7Z2V2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

Sequence Information:

  • Length: 172
  • Mass: 20647
  • Checksum: 305CD12EFE5253EB
  • Sequence:
  • MIYSCCIFVY CMFECFKIKN SVNYHLLFTL VLFSLIVTTV YLKVKEPIFH QVMYGMLVFT 
    LVLRSIYIVT WVYPWLRGLG YTSLGIFLLG FLFWNIDNIF CESLRNFRKK VPPIIGITTQ 
    FHAWWHILTG LGSYLHILFS LYTRTLYLRY RPKVKFLFGI WPVILFEPLR KH

Genular Protein ID: 3604304138

Symbol: B7Z2Q2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

Sequence Information:

  • Length: 230
  • Mass: 27415
  • Checksum: 5B99BD009B2CD6C3
  • Sequence:
  • MAPAADREGY WGPTTSTLDW CEENYSVTWY IAEFLVGMGS WCFHMTLKYE MQLLDELPMI 
    YSCCIFVYCM FECFKIKNSV NYHLLFTLVL FSLIVTTVYL KVKEPIFHQV MYGMLVFTLV 
    LRSIYIVTWV YPWLRGLGYT SLGIFLLGFL FWNIDNIFCE SLRNFRKKVP PIIGITTQFH 
    AWWHILTGLG SYLHILFSLY TRTLYLRYRP KVKFLFGIWP VILFEPLRKH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.