Details for: SHFL

Gene ID: 55337

Symbol: SHFL

Ensembl ID: ENSG00000130813

Description: shiftless antiviral inhibitor of ribosomal frameshifting

Associated with

Other Information

Genular Protein ID: 3723028289

Symbol: SHFL_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9NUL5 A8MQT9 Q4G188 Q8IYH6 Q8N8V1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 EPD 1 Ensembl 3 ExpressionAtlas 1 GO 19 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 RefSeq 3 SAM 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26735137

Title: Characterization of RyDEN (C19orf66) as an interferon-stimulated cellular inhibitor against dengue virus replication.

PubMed ID: 26735137

DOI: 10.1371/journal.ppat.1005357

PubMed ID: 27974568

Title: IRAV (FLJ11286), an Interferon-Stimulated Gene with Antiviral Activity against Dengue Virus, Interacts with MOV10.

PubMed ID: 27974568

DOI: 10.1128/jvi.01606-16

PubMed ID: 30682371

Title: Regulation of HIV-1 Gag-Pol Expression by Shiftless, an Inhibitor of Programmed -1 Ribosomal Frameshifting.

PubMed ID: 30682371

DOI: 10.1016/j.cell.2018.12.030

PubMed ID: 30944177

Title: C19ORF66 Broadly Escapes Virus-Induced Endonuclease Cleavage and Restricts Kaposi's Sarcoma-Associated Herpesvirus.

PubMed ID: 30944177

DOI: 10.1128/jvi.00373-19

PubMed ID: 32150556

Title: C19orf66 interrupts Zika virus replication by inducing lysosomal degradation of viral NS3.

PubMed ID: 32150556

DOI: 10.1371/journal.pntd.0008083

PubMed ID: 32294532

Title: C19orf66 is an interferon-induced inhibitor of HCV replication that restricts formation of the viral replication organelle.

PubMed ID: 32294532

DOI: 10.1016/j.jhep.2020.03.047

Sequence Information:

  • Length: 291
  • Mass: 33110
  • Checksum: D6513814B96BDAF6
  • Sequence:
    • MSQEGVELEK SVRRLREKFH GKVSSKKAGA LMRKFGSDHT GVGRSIVYGV KQKDGQELSN 
DLDAQDPPED MKQDRDIQAV ATSLLPLTEA NLRMFQRAQD DLIPAVDRQF ACSSCDHVWW 
RRVPQRKEVS RCRKCRKRYE PVPADKMWGL AEFHCPKCRH NFRGWAQMGS PSPCYGCGFP 
VYPTRILPPR WDRDPDRRST HTHSCSAADC YNRREPHVPG TSCAHPKSRK QNHLPKVLHP 
SNPHISSGST VATCLSQGGL LEDLDNLILE DLKEEEEEEE EVEDEEGGPR E

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.