Details for: GIMAP5

Gene ID: 55340

Symbol: GIMAP5

Ensembl ID: ENSG00000196329

Description: GTPase, IMAP family member 5

Associated with

Other Information

Genular Protein ID: 3700140972

Symbol: GIMA5_HUMAN

Name: GTPase IMAP family member 5

UniProtKB Accession Codes:

Q96F15 D3DWZ5 Q6IA75 Q96NE4 Q9NUK9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 4 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 1 SAM 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 4 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14724691

Title: hIan5: the human ortholog to the rat Ian4/Iddm1/lyp is a new member of the Ian family that is overexpressed in B-cell lymphoid malignancies.

PubMed ID: 14724691

DOI: 10.1038/sj.gene.6364044

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16509771

Title: IAN family critically regulates survival and development of T lymphocytes.

PubMed ID: 16509771

DOI: 10.1371/journal.pbio.0040103

PubMed ID: 21487483

Title: The autoimmunity-related GIMAP5 GTPase is a lysosome-associated protein.

PubMed ID: 21487483

DOI: 10.4161/self.1.3.12819

PubMed ID: 29382851

Title: Gimap5-dependent inactivation of GSK3beta is required for CD4+ T cell homeostasis and prevention of immune pathology.

PubMed ID: 29382851

DOI: 10.1038/s41467-018-02897-7

PubMed ID: 33956074

Title: GIMAP5 maintains liver endothelial cell homeostasis and prevents portal hypertension.

PubMed ID: 33956074

DOI: 10.1084/jem.20201745

Sequence Information:

  • Length: 307
  • Mass: 34846
  • Checksum: D219F52DE910C5BA
  • Sequence:
    • MGGFQRGKYG TMAEGRSEDN LSATPPALRI ILVGKTGCGK SATGNSILGQ PVFESKLRAQ 
SVTRTCQVKT GTWNGRKVLV VDTPSIFESQ ADTQELYKNI GDCYLLSAPG PHVLLLVIQL 
GRFTAQDTVA IRKVKEVFGT GAMRHVVILF THKEDLGGQA LDDYVANTDN CSLKDLVREC 
ERRYCAFNNW GSVEEQRQQQ AELLAVIERL GREREGSFHS NDLFLDAQLL QRTGAGACQE 
DYRQYQAKVE WQVEKHKQEL RENESNWAYK ALLRVKHLML LHYEIFVFLL LCSILFFIIF 
LFIFHYI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.