Details for: SLC30A10

Gene ID: 55532

Symbol: SLC30A10

Ensembl ID: ENSG00000196660

Description: solute carrier family 30 member 10

Associated with

Other Information

Genular Protein ID: 3165044484

Symbol: ZNT10_HUMAN

Name: Zinc transporter 10

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15154973

Title: In silico identification and expression of SLC30 family genes: an expressed sequence tag data mining strategy for the characterization of zinc transporters' tissue expression.

PubMed ID: 15154973

DOI: 10.1186/1471-2164-5-32

PubMed ID: 22341972

Title: Syndrome of hepatic cirrhosis, dystonia, polycythemia, and hypermanganesemia caused by mutations in SLC30A10, a manganese transporter in man.

PubMed ID: 22341972

DOI: 10.1016/j.ajhg.2012.01.018

PubMed ID: 22341971

Title: Mutations in SLC30A10 cause parkinsonism and dystonia with hypermanganesemia, polycythemia, and chronic liver disease.

PubMed ID: 22341971

DOI: 10.1016/j.ajhg.2012.01.017

PubMed ID: 22706290

Title: Efflux function, tissue-specific expression and intracellular trafficking of the Zn transporter ZnT10 indicate roles in adult Zn homeostasis.

PubMed ID: 22706290

DOI: 10.1039/c2mt20088k

PubMed ID: 22427991

Title: Angiotensin II requires zinc and downregulation of the zinc transporters ZnT3 and ZnT10 to induce senescence of vascular smooth muscle cells.

PubMed ID: 22427991

DOI: 10.1371/journal.pone.0033211

PubMed ID: 25319704

Title: SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activity.

PubMed ID: 25319704

DOI: 10.1523/jneurosci.2329-14.2014

PubMed ID: 25582195

Title: The zinc finger protein ZNF658 regulates the transcription of genes involved in zinc homeostasis and affects ribosome biogenesis through the zinc transcriptional regulatory element.

PubMed ID: 25582195

DOI: 10.1128/mcb.01298-14

PubMed ID: 27226609

Title: Direct comparison of manganese detoxification/efflux proteins and molecular characterization of ZnT10 protein as a manganese transporter.

PubMed ID: 27226609

DOI: 10.1074/jbc.m116.728014

PubMed ID: 27307044

Title: Structural elements in the transmembrane and cytoplasmic domains of the metal transporter SLC30A10 are required for its manganese efflux activity.

PubMed ID: 27307044

DOI: 10.1074/jbc.m116.726935

PubMed ID: 26728129

Title: Differential targeting of SLC30A10/ZnT10 heterodimers to endolysosomal compartments modulates EGF-induced MEK/ERK1/2 activity.

PubMed ID: 26728129

DOI: 10.1111/tra.12371

PubMed ID: 30755481

Title: Zinc transporter 10 (ZnT10)-dependent extrusion of cellular Mn2+ is driven by an active Ca2+-coupled exchange.

PubMed ID: 30755481

DOI: 10.1074/jbc.ra118.006816

Sequence Information:

  • Length: 485
  • Mass: 52684
  • Checksum: 96A3495EF026DE94
  • Sequence:
  • MGRYSGKTCR LLFMLVLTVA FFVAELVSGY LGNSIALLSD SFNMLSDLIS LCVGLSAGYI 
    ARRPTRGFSA TYGYARAEVV GALSNAVFLT ALCFTIFVEA VLRLARPERI DDPELVLIVG 
    VLGLLVNVVG LLIFQDCAAW FACCLRGRSR RLQQRQQLAE GCVPGAFGGP QGAEDPRRAA 
    DPTAPGSDSA VTLRGTSVER KREKGATVFA NVAGDSFNTQ NEPEDMMKKE KKSEALNIRG 
    VLLHVMGDAL GSVVVVITAI IFYVLPLKSE DPCNWQCYID PSLTVLMVII ILSSAFPLIK 
    ETAAILLQMV PKGVNMEELM SKLSAVPGIS SVHEVHIWEL VSGKIIATLH IKYPKDRGYQ 
    DASTKIREIF HHAGIHNVTI QFENVDLKEP LEQKDLLLLC NSPCISKGCA KQLCCPPGAL 
    PLAHVNGCAE HNGGPSLDTY GSDGLSRRDA REVAIEVSLD SCLSDHGQSL NKTQEDQCYV 
    NRTHF

Genular Protein ID: 99051726

Symbol: B3KR19_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 260
  • Mass: 28596
  • Checksum: B45A4005768C31AE
  • Sequence:
  • MMKKEKKSEA LNIRGVLLHV MGDALGSVVV VITAIIFYVL PLKSEDPCNW QCYIDPSLTV 
    LMVIIILSSA FPLIKETAAI LLQMVPKGVN MEELMSKLSA VPGISSVHEV HIWELVSGKI 
    IATLHIKYPK DRGYQDASTK IREIFHHAGI HNVTIQFENV DLKEPLEQKD LLLLCNSPCI 
    SKGCAKQLCC PPGALPLAHV NGCAEHNGGP SLDTYGSDGL SRRDAREVAI EVSLDSCLSD 
    HGQSLNKTQE DQCYVNRTHF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.