MAML3 | ENSG00000196782 | NCBI 55534

Details for: MAML3

Gene ID: 55534

Symbol: MAML3

Ensembl ID: ENSG00000196782

Description: mastermind like transcriptional coactivator 3

Associated with

Constitutive signaling by notch1 hd+pest domain mutants
(R-HSA-2894862)
Constitutive signaling by notch1 pest domain mutants
(R-HSA-2644606)
Developmental biology
(R-HSA-1266738)
Disease
(R-HSA-1643685)
Diseases of signal transduction by growth factor receptors and second messengers
(R-HSA-5663202)
Formation of paraxial mesoderm
(R-HSA-9793380)
Gastrulation
(R-HSA-9758941)
Gene expression (transcription)
(R-HSA-74160)
Generic transcription pathway
(R-HSA-212436)
Notch-hlh transcription pathway
(R-HSA-350054)
Notch1 intracellular domain regulates transcription
(R-HSA-2122947)
Notch2 intracellular domain regulates transcription
(R-HSA-2197563)
Notch3 intracellular domain regulates transcription
(R-HSA-9013508)
Notch4 intracellular domain regulates transcription
(R-HSA-9013695)
Pre-notch expression and processing
(R-HSA-1912422)
Pre-notch transcription and translation
(R-HSA-1912408)
Regulation of beta-cell development
(R-HSA-186712)
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
(R-HSA-210744)
Rna polymerase ii transcription
(R-HSA-73857)
Runx3 regulates notch signaling
(R-HSA-8941856)
Signaling by notch
(R-HSA-157118)
Signaling by notch1
(R-HSA-1980143)
Signaling by notch1 hd+pest domain mutants in cancer
(R-HSA-2894858)
Signaling by notch1 in cancer
(R-HSA-2644603)
Signaling by notch1 pest domain mutants in cancer
(R-HSA-2644602)
Signaling by notch2
(R-HSA-1980145)
Signaling by notch3
(R-HSA-9012852)
Signaling by notch4
(R-HSA-9013694)
Signal transduction
(R-HSA-162582)
Transcriptional regulation by runx3
(R-HSA-8878159)
Notch signaling pathway
(GO:0007219)
Nuclear speck
(GO:0016607)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Positive regulation of transcription of notch receptor target
(GO:0007221)
Protein binding
(GO:0005515)
Transcription coactivator activity
(GO:0003713)

Other Information

Proteins

Mastermind-like protein 3
Q9NPV6_HUMAN

Genular Protein ID: 3965824740

Symbol: MAML3_HUMAN

Name: Mastermind-like protein 3

UniProtKB Accession Codes:

Q96JK9 B2RNU9 B3KVV7 E7EVW8

Database IDs:

Citations:

PubMed ID: 11347906

Title: Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 11347906

DOI: 10.1093/dnares/8.2.85

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12386158

Title: Identification of new human mastermind proteins defines a family that consists of positive regulators for Notch signaling.

PubMed ID: 12386158

DOI: 10.1074/jbc.m209529200

PubMed ID: 12370315

Title: Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

PubMed ID: 12370315

DOI: 10.1128/mcb.22.21.7688-7700.2002

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

Sequence Information:

Length: 1138
Mass: 122293
Checksum: 145C1CA5F2F7EEB0
Sequence:

MGDFAAPAAA ANGSSICINS SLNSSLGGAG IGVNNTPNST PAAPSSNHPA AGGCGGSGGP 
GGGSAAVPKH STVVERLRQR IEGCRRHHVN CENRYQQAQV EQLELERRDT VSLYQRTLEQ 
RAKKSGAGTG KQQHPSKPQQ DAEAASAEQR NHTLIMLQET VKRKLEGARS PLNGDQQNGA 
CDGNFSPTSK RIRKDISAGM EAINNLPSNM PLPSASPLHQ LDLKPSLPLQ NSGTHTPGLL 
EDLSKNGRLP EIKLPVNGCS DLEDSFTILQ SKDLKQEPLD DPTCIDTSET SLSNQNKLFS 
DINLNDQEWQ ELIDELANTV PEDDIQDLFN EDFEEKKEPE FSQPATETPL SQESASVKSD 
PSHSPFAHVS MGSPQARPSS SGPPFSTVST ATSLPSVAST PAAPNPASSP ANCAVQSPQT 
PNQAHTPGQA PPRPGNGYLL NPAAVTVAGS ASGPVAVPSS DMSPAEQLKQ MAAQQQQRAK 
LMQQKQQQQQ QQQQQQQQQQ QQQQQQQQQQ HSNQTSNWSP LGPPSSPYGA AFTAEKPNSP 
MMYPQAFNNQ NPIVPPMANN LQKTTMNNYL PQNHMNMINQ QPNNLGTNSL NKQHNILTYG 
NTKPLTHFNA DLSQRMTPPV ANPNKNPLMP YIQQQQQQQQ QQQQQQQQQQ PPPPQLQAPR 
AHLSEDQKRL LLMKQKGVMN QPMAYAALPS HGQEQHPVGL PRTTGPMQSS VPPGSGGMVS 
GASPAGPGFL GSQPQAAIMK QMLIDQRAQL IEQQKQQFLR EQRQQQQQQQ QQILAEQQLQ 
QSHLPRQHLQ PQRNPYPVQQ VNQFQGSPQD IAAVRSQAAL QSMRTSRLMA QNAGMMGIGP 
SQNPGTMATA AAQSEMGLAP YSTTPTSQPG MYNMSTGMTQ MLQHPNQSGM SITHNQAQGP 
RQPASGQGVG MVSGFGQSML VNSAITQQHP QMKGPVGQAL PRPQAPPRLQ SLMGTVQQGA 
QSWQQRSLQG MPGRTSGELG PFNNGASYPL QAGQPRLTKQ HFPQGLSQSV VDANTGTVRT 
LNPAAMGRQM MPSLPGQQGT SQARPMVMSG LSQGVPGMPA FSQPPAQQQI PSGSFAPSSQ 
SQAYERNAPQ DVSYNYSGDG AGGSFPGLPD GADLVDSIIK GGPGDEWMQE LDELFGNP

Genular Protein ID: 2819791327

Symbol: Q9NPV6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9NPV6

Database IDs:

Sequence Information:

Length: 171
Mass: 17778
Checksum: FA80ABC4CF41705E
Sequence:

LQGMPGRTSG ELGPFNNGAS YPLQAGQPRL TKQHFPQGLS QSVVDANTGT VRTLNPAAMG 
RQMMPSLPGQ QGTSQARPMV MSGLSQGVPG MPAFSQPPAQ QQIPSGSFAP SSQSQAYERN 
APQDVSYNYS GDGAGGSFPG LPDGADLVDS IIKGGPGDEW MQELDELFGN P

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: MAML3

Associated with

Other Information

Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. PubMed ID: 11347906

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Generation and annotation of the DNA sequences of human chromosomes 2 and 4. PubMed ID: 15815621

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification of new human mastermind proteins defines a family that consists of positive regulators for Notch signaling. PubMed ID: 12386158

Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors. PubMed ID: 12370315

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861