Details for: FERMT1

Gene ID: 55612

Symbol: FERMT1

Ensembl ID: ENSG00000101311

Description: FERM domain containing kindlin 1

Associated with

Other Information

Genular Protein ID: 1749420737

Symbol: FERM1_HUMAN

Name: Fermitin family homolog 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12697302

Title: URP1: a member of a novel family of PH and FERM domain-containing membrane-associated proteins is significantly over-expressed in lung and colon carcinomas.

PubMed ID: 12697302

DOI: 10.1016/s0925-4439(03)00035-8

PubMed ID: 12789646

Title: Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome.

PubMed ID: 12789646

DOI: 10.1086/376609

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12668616

Title: Identification of mutations in a new gene encoding a FERM family protein with a pleckstrin homology domain in Kindler syndrome.

PubMed ID: 12668616

DOI: 10.1093/hmg/ddg097

PubMed ID: 14634021

Title: The Kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion.

PubMed ID: 14634021

DOI: 10.1074/jbc.m307978200

PubMed ID: 17012746

Title: Kindlin-1 is a phosphoprotein involved in regulation of polarity, proliferation, and motility of epidermal keratinocytes.

PubMed ID: 17012746

DOI: 10.1074/jbc.m606259200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19804783

Title: The structure of the N-terminus of kindlin-1: a domain important for alphaIIbbeta3 integrin activation.

PubMed ID: 19804783

DOI: 10.1016/j.jmb.2009.09.061

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 21936020

Title: Kindler syndrome: extension of FERMT1 mutational spectrum and natural history.

PubMed ID: 21936020

DOI: 10.1002/humu.21576

Sequence Information:

  • Length: 677
  • Mass: 77437
  • Checksum: 7354DCD84C516F90
  • Sequence:
  • MLSSTDFTFA SWELVVRVDH PNEEQQKDVT LRVSGDLHVG GVMLKLVEQI NISQDWSDFA 
    LWWEQKHCWL LKTHWTLDKY GVQADAKLLF TPQHKMLRLR LPNLKMVRLR VSFSAVVFKA 
    VSDICKILNI RRSEELSLLK PSGDYFKKKK KKDKNNKEPI IEDILNLESS PTASGSSVSP 
    GLYSKTMTPI YDPINGTPAS STMTWFSDSP LTEQNCSILA FSQPPQSPEA LADMYQPRSL 
    VDKAKLNAGW LDSSRSLMEQ GIQEDEQLLL RFKYYSFFDL NPKYDAVRIN QLYEQARWAI 
    LLEEIDCTEE EMLIFAALQY HISKLSLSAE TQDFAGESEV DEIEAALSNL EVTLEGGKAD 
    SLLEDITDIP KLADNLKLFR PKKLLPKAFK QYWFIFKDTS IAYFKNKELE QGEPLEKLNL 
    RGCEVVPDVN VAGRKFGIKL LIPVADGMNE MYLRCDHENQ YAQWMAACML ASKGKTMADS 
    SYQPEVLNIL SFLRMKNRNS ASQVASSLEN MDMNPECFVS PRCAKRHKSK QLAARILEAH 
    QNVAQMPLVE AKLRFIQAWQ SLPEFGLTYY LVRFKGSKKD DILGVSYNRL IKIDAATGIP 
    VTTWRFTNIK QWNVNWETRQ VVIEFDQNVF TAFTCLSADC KIVHEYIGGY IFLSTRSKDQ 
    NETLDEDLFH KLTGGQD

Genular Protein ID: 374679554

Symbol: Q54A15_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 677
  • Mass: 77409
  • Checksum: 40A17D514C49FE13
  • Sequence:
  • MLSSTDFTFA SWELVVRVDH PNEEQQKDVT LRVSGDLHVG GVMLKLVEQI NISQDWSDFA 
    LWWEQKHCWL LKTHWTLDKY GVQADAKLLF TPQHKMLRLR LPNLKMVRLR VSFSAVVFKA 
    VSDICKILNI RRSEELSLLK PSGDYFKKKK KKDKNNKEPI IEDILNLESS PTASGSSVSP 
    GLYSKTMTPI YDPINGTPAS STMTWFSDSP LTEQNCSILA FSQPPQSPEA LADMYQPRSL 
    VDKAKLNAGW LDSSRSLMEQ GIQEDEQLLL RFKYYSFFDL NPKYDAVRIN QLYEQARWAI 
    LLEEIDCTEE EMLIFAALQY HISKLSLSAE TQDFAGESEV DEIEAALSNL EVTLEGGKAD 
    SLLEDITDIP KLADNLKLFR PKKLLPKAFK QYWFIFKDTS IAYFKNKELE QGEPLEKLNL 
    RGCEVVPDVN VAGRKFGIKL LIPVADGMNE MYLRCDHENQ YAQWMAACML ASKGKTMADS 
    SYQPEVLNIL SFLRMKNRNS ASQVASSLEN MDMNPECFVS PRCAKKHKSK QLAARILEAH 
    QNVAQMPLVE AKLRFIQAWQ SLPEFGLTYY LVRFKGSKKD DILGVSYNRL IKIDAATGIP 
    VTTWRFTNIK QWNVNWETRQ VVIEFDQNVF TAFTCLSADC KIVHEYIGGY IFLSTRSKDQ 
    NETLDEDLFH KLTGGQD

Genular Protein ID: 3737641797

Symbol: Q49AC8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 420
  • Mass: 48267
  • Checksum: 378D0F836A3BA1AA
  • Sequence:
  • MEQGIKEDEQ LLLRFKYYSF FDLNPKYDAV QINQLYEQAR WAILLEEIDC TEEEMLIFAA 
    LQYHISKLSL SAETQDFAGE SEVDEIEAAL SNLEVTLEGG KADSLLEDIT DIPKLADNLK 
    LFRPKKLLPK AFKQYWFIFK DTSIAYFKNK ELEQGEPLEK LNLRGCEVVP DVNVAGRKFG 
    IKLLIPVADG MNEMYLRCDH ENQYAQWMAA CMLASKGKTM ADSSYQPEVL NILSFLRMKN 
    RNSASQVASS LENMDMNPEC FVSPRCAKRH KSKQLAARIL EAHQNVAQMP LVEAKLRFIQ 
    AWQSLPEFGL TYYLVRFKGS KKDDILGVSY NRLIKIDAAT GIPVTTWRFT NIKQWNVNWE 
    TRQVVIEFDQ NVFTAFTCLS ADCKIVHEYI GGYIFLSTRS KDQNETLDED LFHKLTGGQD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.