PRR5 | ENSG00000186654 | NCBI 55615

Details for: PRR5

Gene ID: 55615

Symbol: PRR5

Ensembl ID: ENSG00000186654

Description: proline rich 5

Associated with

Adaptive immune system
(R-HSA-1280218)
Cd28 co-stimulation
(R-HSA-389356)
Cd28 dependent pi3k/akt signaling
(R-HSA-389357)
Constitutive signaling by akt1 e17k in cancer
(R-HSA-5674400)
Costimulation by the cd28 family
(R-HSA-388841)
Disease
(R-HSA-1643685)
Diseases of signal transduction by growth factor receptors and second messengers
(R-HSA-5663202)
Gene expression (transcription)
(R-HSA-74160)
Generic transcription pathway
(R-HSA-212436)
Immune system
(R-HSA-168256)
Intracellular signaling by second messengers
(R-HSA-9006925)
Pi3k/akt signaling in cancer
(R-HSA-2219528)
Pip3 activates akt signaling
(R-HSA-1257604)
Regulation of tp53 activity
(R-HSA-5633007)
Regulation of tp53 degradation
(R-HSA-6804757)
Regulation of tp53 expression and degradation
(R-HSA-6806003)
Rna polymerase ii transcription
(R-HSA-73857)
Signaling by receptor tyrosine kinases
(R-HSA-9006934)
Signaling by vegf
(R-HSA-194138)
Signal transduction
(R-HSA-162582)
Transcriptional regulation by tp53
(R-HSA-3700989)
Vegfa-vegfr2 pathway
(R-HSA-4420097)
Vegfr2 mediated vascular permeability
(R-HSA-5218920)
Cell cycle
(GO:0007049)
Cellular response to nutrient levels
(GO:0031669)
Cytoskeleton organization
(GO:0007010)
Cytosol
(GO:0005829)
Negative regulation of apoptotic process
(GO:0043066)
Phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0043491)
Positive regulation of cell growth
(GO:0030307)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein binding
(GO:0005515)
Torc2 complex
(GO:0031932)
Torc2 signaling
(GO:0038203)

Other Information

Proteins

Proline-rich protein 5

Genular Protein ID: 3434410928

Symbol: PRR5_HUMAN

Name: Proline-rich protein 5

UniProtKB Accession Codes:

P85299 B1AHF6 B1AHG5 B3KP73 O75983 O95695 Q5BIW2 Q5EAJ8 Q5EAJ9 Q5XKJ6 Q96RW1 Q96RW2 Q9HA49 Q9HC46 Q9NSG0 Q9NVX8 Q9NXL1 Q9UH20

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15498874

Title: Large-scale cDNA transfection screening for genes related to cancer development and progression.

PubMed ID: 15498874

DOI: 10.1073/pnas.0404089101

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15718101

Title: PRR5 encodes a conserved proline-rich protein predominant in kidney: analysis of genomic organization, expression, and mutation status in breast and colorectal carcinomas.

PubMed ID: 15718101

DOI: 10.1016/j.ygeno.2004.11.002

PubMed ID: 17461779

Title: Identification of Protor as a novel Rictor-binding component of mTOR complex-2.

PubMed ID: 17461779

DOI: 10.1042/bj20070540

PubMed ID: 17599906

Title: PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.

PubMed ID: 17599906

DOI: 10.1074/jbc.m704343200

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

Length: 388
Mass: 42753
Checksum: FA6B90495623EF3F
Sequence:

MRTLRRLKFM SSPSLSDLGK REPAAAADER GTQQRRACAN ATWNSIHNGV IAVFQRKGLP 
DQELFSLNEG VRQLLKTELG SFFTEYLQNQ LLTKGMVILR DKIRFYEGQK LLDSLAETWD 
FFFSDVLPML QAIFYPVQGK EPSVRQLALL HFRNAITLSV KLEDALARAH ARVPPAIVQM 
LLVLQGVHES RGVTEDYLRL ETLVQKVVSP YLGTYGLHSS EGPFTHSCIL EKRLLRRSRS 
GDVLAKNPVV RSKSYNTPLL NPVQEHEAEG AAAGGTSIRR HSVSEMTSCP EPQGFSDPPG 
QGPTGTFRSS PAPHSGPCPS RLYPTTQPPE QGLDPTRSSL PRSSPENLVD QILESVDSDS 
EGIFIDFGRG RGSGMSDLEG SGGRQSVV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: PRR5

Associated with

Other Information

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Large-scale cDNA transfection screening for genes related to cancer development and progression. PubMed ID: 15498874

The DNA sequence of human chromosome 22. PubMed ID: 10591208

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

PRR5 encodes a conserved proline-rich protein predominant in kidney: analysis of genomic organization, expression, and mutation status in breast and colorectal carcinomas. PubMed ID: 15718101

Identification of Protor as a novel Rictor-binding component of mTOR complex-2. PubMed ID: 17461779

PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling. PubMed ID: 17599906

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569