Details for: POMGNT1

Gene ID: 55624

Symbol: POMGNT1

Ensembl ID: ENSG00000085998

Description: protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)

Associated with

Other Information

Genular Protein ID: 1442263773

Symbol: PMGT1_HUMAN

Name: Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11709191

Title: Muscular dystrophy and neuronal migration disorder caused by mutations in a glycosyltransferase, POMGnT1.

PubMed ID: 11709191

DOI: 10.1016/s1534-5807(01)00070-3

PubMed ID: 12588800

Title: Worldwide distribution and broader clinical spectrum of muscle-eye-brain disease.

PubMed ID: 12588800

DOI: 10.1093/hmg/ddg043

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11742540

Title: Cloning and expression of a novel UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.

PubMed ID: 11742540

DOI: 10.1042/0264-6021:3610153

PubMed ID: 17034757

Title: Molecular interaction between fukutin and POMGnT1 in the glycosylation pathway of alpha-dystroglycan.

PubMed ID: 17034757

DOI: 10.1016/j.bbrc.2006.09.129

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28512129

Title: Mammalian O-mannosylation of cadherins and plexins is independent of protein O-mannosyltransferases 1 and 2.

PubMed ID: 28512129

DOI: 10.1074/jbc.m117.794487

PubMed ID: 12788071

Title: Loss-of-function of an N-acetylglucosaminyltransferase, POMGnT1, in muscle-eye-brain disease.

PubMed ID: 12788071

DOI: 10.1016/s0006-291x(03)00924-0

PubMed ID: 15207699

Title: Structure-function analysis of human protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase 1, POMGnT1.

PubMed ID: 15207699

DOI: 10.1016/j.bbrc.2004.05.129

PubMed ID: 27493216

Title: Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of alpha-dystroglycan.

PubMed ID: 27493216

DOI: 10.1073/pnas.1525545113

PubMed ID: 15236414

Title: POMGnT1 gene alterations in a family with neurological abnormalities.

PubMed ID: 15236414

DOI: 10.1002/ana.20172

PubMed ID: 15466003

Title: POMGnT1 mutation and phenotypic spectrum in muscle-eye-brain disease.

PubMed ID: 15466003

DOI: 10.1136/jmg.2004.020701

PubMed ID: 17030669

Title: POMGnT1 mutations in congenital muscular dystrophy: genotype-phenotype correlation and expanded clinical spectrum.

PubMed ID: 17030669

DOI: 10.1001/archneur.63.10.1491

PubMed ID: 19067344

Title: Brain involvement in muscular dystrophies with defective dystroglycan glycosylation.

PubMed ID: 19067344

DOI: 10.1002/ana.21482

PubMed ID: 18195152

Title: Mild POMGnT1 mutations underlie a novel limb-girdle muscular dystrophy variant.

PubMed ID: 18195152

DOI: 10.1001/archneurol.2007.2

PubMed ID: 19299310

Title: Congenital muscular dystrophies with defective glycosylation of dystroglycan: a population study.

PubMed ID: 19299310

DOI: 10.1212/01.wnl.0000346518.68110.60

PubMed ID: 26908613

Title: Mutations in POMGNT1 cause non-syndromic retinitis pigmentosa.

PubMed ID: 26908613

DOI: 10.1093/hmg/ddw022

PubMed ID: 27391550

Title: Homozygosity Mapping and Whole-Genome Sequencing Links a Missense Mutation in POMGNT1 to Autosomal Recessive Retinitis Pigmentosa.

PubMed ID: 27391550

DOI: 10.1167/iovs.16-19463

Sequence Information:

  • Length: 660
  • Mass: 75252
  • Checksum: C58D0E543E033F17
  • Sequence:
  • MDDWKPSPLI KPFGARKKRS WYLTWKYKLT NQRALRRFCQ TGAVLFLLVT VIVNIKLILD 
    TRRAISEANE DPEPEQDYDE ALGRLEPPRR RGSGPRRVLD VEVYSSRSKV YVAVDGTTVL 
    EDEAREQGRG IHVIVLNQAT GHVMAKRVFD TYSPHEDEAM VLFLNMVAPG RVLICTVKDE 
    GSFHLKDTAK ALLRSLGSQA GPALGWRDTW AFVGRKGGPV FGEKHSKSPA LSSWGDPVLL 
    KTDVPLSSAE EAECHWADTE LNRRRRRFCS KVEGYGSVCS CKDPTPIEFS PDPLPDNKVL 
    NVPVAVIAGN RPNYLYRMLR SLLSAQGVSP QMITVFIDGY YEEPMDVVAL FGLRGIQHTP 
    ISIKNARVSQ HYKASLTATF NLFPEAKFAV VLEEDLDIAV DFFSFLSQSI HLLEEDDSLY 
    CISAWNDQGY EHTAEDPALL YRVETMPGLG WVLRRSLYKE ELEPKWPTPE KLWDWDMWMR 
    MPEQRRGREC IIPDVSRSYH FGIVGLNMNG YFHEAYFKKH KFNTVPGVQL RNVDSLKKEA 
    YEVEVHRLLS EAEVLDHSKN PCEDSFLPDT EGHTYVAFIR MEKDDDFTTW TQLAKCLHIW 
    DLDVRGNHRG LWRLFRKKNH FLMVGVPASP YSVKKPPSVT PIFLEPPPKE EGAPGAPEQT

Genular Protein ID: 1616163094

Symbol: B7Z7F2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 517
  • Mass: 58765
  • Checksum: A0825F828D5AA522
  • Sequence:
  • MAKSVFDTYS PHEDEAMVLF LNMVAPGRVL ICTVKDEGSF HLKDTAKALL RSLGSQAGPA 
    LGWRDTWAFV GRKGGPVFGE KHSKSPALSS WGDPVLLKTD VPLSSAEEAE CHWADTELNR 
    RRRRFCSKVE GYGSVCSCKD PTPIEFSPDP LPDNKVLNVP VAVIAGNRPN YLYRMLRSLL 
    SAQGVSPQMI TVFIDGYYEE PMDVVALFGL RGIQHTPISI KNARVSQHYK ASLTATFNLF 
    PEAKFAVVLE EDLDIAVDFF SFLSQSIHLL EEDDSLYCIS AWNDQGYEHT AEDPALLYRV 
    ETMPGLGWVL RRSLYKEELE PKWPTPEKLW DWDMWMRMPE QRRGRECIIP DVSRSYHFGI 
    VGLNMNGYFH EAYFKKHKFN TVPGVQLRNV DSLKKEAYEV EVHRLLSEAE VLDHSKNPCE 
    DSFLPDTEGH TYVAFIRMEK DDDFTTWTQL AKCLHIWDLD VRGNHRGLWR LFRKKNHFLV 
    VGVPASPYSV KKPPSVTPIF LEPPPKEEGA PGAPEQT

Genular Protein ID: 2220821799

Symbol: A0A8I5KNB7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

Sequence Information:

  • Length: 718
  • Mass: 81703
  • Checksum: F5BEE0647D31EEE4
  • Sequence:
  • MDDWKPSPLI KPFGARKKRS WYLTWKYKLT NQRALRRFCQ TGAVLFLLVT VIVNIKLILD 
    TRRAISEANE DPEPEQDYDE ALGRLEPPRR RGSGPRRVLD VEVYSSRSKV YVAVDGTTVL 
    EDEAREQGRG IHVIVLNQAT GHVMAKRVFD TYSPHEDEAM VLFLNMVAPG RVLICTVKDE 
    GSFHLKDTAK ALLRSLGSQA GPALGWRDTW AFVGRKGGPV FGEKHSKSPA LSSWGDPVLL 
    KTDVPLSSAE EAECHWADTE LNRRRRRFCS KVEGYGSVCS CKDPTPIEFS PDPLPDNKVL 
    NVPVAVIAGN RPNYLYRMLR SLLSAQGVSP QMITVFIDGY YEEPMDVVAL FGLRGIQHTP 
    ISIKNARVSQ HYKASLTATF NLFPEAKFAV VLEEDLDIAV DFFSFLSQSI HLLEEDDSLY 
    CISAWNDQGY EHTAEDPALL YRVETMPGLG WVLRRSLYKE ELEPKWPTPE KLWDWDMWMR 
    MPEQRRGREC IIPDVSRSYH FGIVGLNMNG YFHEAYFKKH KFNTVPGVQL RNVDSLKKEA 
    YEVEVHRLLS EAEVLDHSKN PCEDSFLPDT EGHTYVAFIR MEKDDDFTTW TQLAKCLHIW 
    DLDVRGNHRG LWRLFRKKNH FLMVGVPASP YSPGSESNLF IDCPEGLENR PNLEGLDFFL 
    GWNAALRVGL ALTQETAVPN PWTGPAGAHM LTQTHSETLR HWTRPPLSLL FVQISKAG

Genular Protein ID: 1544320144

Symbol: B7Z7Q4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 638
  • Mass: 72447
  • Checksum: 6B9D4E06B80E7116
  • Sequence:
  • MEGTKEIKVS NRRIQEHWTG AVLFLLVTVI VNIKLILDTR RAISEANEDP EPEQDYDEAL 
    GRLEPPRRRG SGPRRVLDVE VYSSRSKVYV AVDGTTVLED EAREQGRGIH VIVLNQATGH 
    VMAKRVFDTY SPHEDEAMVL FLNMVAPGRV LICTVKDEGS FHLKDTAKAL LRSLGSQAGP 
    ALGWRDTWAF VGRKGGPVFG EKHSKSPALS SWGDPVLLKT DVPLSSAEEA ECHWADTELN 
    RRRRRFCSKV EGYGSVCSCK DPTPIEFSPD PLPDNKVLNV PVAVIAGNRP NYLYRMLRSL 
    LSAQGVSPQM ITVFIDGYYE EPMDVVALFG LRGIQHTPIS IKNARVSQHY KASLTATFNL 
    FPEAKFAVVL EEDLDIAVDF FSFLSQSIHL LEEDDSLYCI SAWNDQGYEH TAEDPALLYR 
    VETMPGLGWV LRRSLYKEEL EPKWPTPEKL WDWDMWMRMP EQRRGRECII PDVSRSYHFG 
    IVGLNMNGYF HEAYFKKHKF NTVPGVQLRN VDSLKKEAYE VEVHRLLSEA EVLDHSKNPC 
    EDSFLPDTEG HTYVAFIRME KDDDFTTWTQ LAKCLHIWDL DVRGNHRGLW RLFRKKNHFL 
    VVGVPASPYS VKKPPSVTPI FLEPPPKEEG APGAPEQT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.