NPLOC4 | ENSG00000182446 | NCBI 55666

Details for: NPLOC4

Gene ID: 55666

Symbol: NPLOC4

Ensembl ID: ENSG00000182446

Description: NPL4 homolog, ubiquitin recognition factor

Associated with

Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Cellular response to chemical stress
(R-HSA-9711123)
Dna damage bypass
(R-HSA-73893)
Dna repair
(R-HSA-73894)
Keap1-nfe2l2 pathway
(R-HSA-9755511)
Metabolism of proteins
(R-HSA-392499)
Neddylation
(R-HSA-8951664)
Post-translational protein modification
(R-HSA-597592)
Translesion synthesis by polh
(R-HSA-110320)
Translesion synthesis by y family dna polymerases bypasses lesions on dna template
(R-HSA-110313)
Atpase binding
(GO:0051117)
Cytosol
(GO:0005829)
Endoplasmic reticulum
(GO:0005783)
Erad pathway
(GO:0036503)
Golgi organization
(GO:0007030)
K48-linked polyubiquitin modification-dependent protein binding
(GO:0036435)
K63-linked polyubiquitin modification-dependent protein binding
(GO:0070530)
Metal ion binding
(GO:0046872)
Negative regulation of rig-i signaling pathway
(GO:0039536)
Negative regulation of type i interferon production
(GO:0032480)
Nuclear outer membrane-endoplasmic reticulum membrane network
(GO:0042175)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Retrograde protein transport, er to cytosol
(GO:0030970)
Ubiquitin-dependent protein catabolic process
(GO:0006511)
Ubiquitin binding
(GO:0043130)
Ubiquitin protein ligase binding
(GO:0031625)
Ufd1-npl4 complex
(GO:0036501)
Vcp-npl4-ufd1 aaa atpase complex
(GO:0034098)

Other Information

Proteins

Nuclear protein localization protein 4 homolog

Genular Protein ID: 3298104075

Symbol: NPL4_HUMAN

Name: Nuclear protein localization protein 4 homolog

UniProtKB Accession Codes:

Q8TAT6 Q8N3J1 Q9H8V2 Q9H964 Q9NWR5 Q9P229

Database IDs:

Citations:

PubMed ID: 10819331

Title: Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10819331

DOI: 10.1093/dnares/7.2.143

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 11574150

Title: Cloning and characterization of the gene encoding human NPL4, a protein interacting with the ubiquitin fusion-degradation protein (UFD1L).

PubMed ID: 11574150

DOI: 10.1016/s0378-1119(01)00649-7

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24160817

Title: Signal-peptide-mediated translocation is regulated by a p97-AIRAPL complex.

PubMed ID: 24160817

DOI: 10.1042/bj20130710

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26471729

Title: A non-canonical role of the p97 complex in RIG-I antiviral signaling.

PubMed ID: 26471729

DOI: 10.15252/embj.201591888

Sequence Information:

Length: 608
Mass: 68120
Checksum: 6ED6A0145F15C01D
Sequence:

MAESIIIRVQ SPDGVKRITA TKRETAATFL KKVAKEFGFQ NNGFSVYINR NKTGEITASS 
NKSLNLLKIK HGDLLFLFPS SLAGPSSEME TSVPPGFKVF GAPNVVEDEI DQYLSKQDGK 
IYRSRDPQLC RHGPLGKCVH CVPLEPFDED YLNHLEPPVK HMSFHAYIRK LTGGADKGKF 
VALENISCKI KSGCEGHLPW PNGICTKCQP SAITLNRQKY RHVDNIMFEN HTVADRFLDF 
WRKTGNQHFG YLYGRYTEHK DIPLGIRAEV AAIYEPPQIG TQNSLELLED PKAEVVDEIA 
AKLGLRKVGW IFTDLVSEDT RKGTVRYSRN KDTYFLSSEE CITAGDFQNK HPNMCRLSPD 
GHFGSKFVTA VATGGPDNQV HFEGYQVSNQ CMALVRDECL LPCKDAPELG YAKESSSEQY 
VPDVFYKDVD KFGNEITQLA RPLPVEYLII DITTTFPKDP VYTFSISQNP FPIENRDVLG 
ETQDFHSLAT YLSQNTSSVF LDTISDFHLL LFLVTNEVMP LQDSISLLLE AVRTRNEELA 
QTWKRSEQWA TIEQLCSTVG GQLPGLHEYG AVGGSTHTAT AAMWACQHCT FMNQPGTGHC 
EMCSLPRT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: NPLOC4

Associated with

Other Information

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. PubMed ID: 10819331

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. PubMed ID: 12665801

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

Cloning and characterization of the gene encoding human NPL4, a protein interacting with the ubiquitin fusion-degradation protein (UFD1L). PubMed ID: 11574150

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Initial characterization of the human central proteome. PubMed ID: 21269460

Signal-peptide-mediated translocation is regulated by a p97-AIRAPL complex. PubMed ID: 24160817

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

A non-canonical role of the p97 complex in RIG-I antiviral signaling. PubMed ID: 26471729