Associated with
Other Information
Genular Protein ID: 819671568
Symbol: MFN1_HUMAN
Name: Mitofusin-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181170
Title: Control of mitochondrial morphology by a human mitofusin.
PubMed ID: 11181170
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9230308
Title: Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase.
PubMed ID: 9230308
PubMed ID: 11751411
Title: Novel transmembrane GTPase of non-small cell lung cancer identified by mRNA differential display.
PubMed ID: 11751411
PubMed ID: 11950885
Title: Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo.
PubMed ID: 11950885
PubMed ID: 12475957
Title: Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins.
PubMed ID: 12475957
PubMed ID: 12759376
Title: Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells.
PubMed ID: 12759376
DOI: 10.1242/jcs.00479
PubMed ID: 20103533
Title: Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1.
PubMed ID: 20103533
DOI: 10.1242/jcs.061481
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23933751
Title: The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy.
PubMed ID: 23933751
DOI: 10.1038/nn.3489
PubMed ID: 25008184
Title: IHG-1 increases mitochondrial fusion and bioenergetic function.
PubMed ID: 25008184
DOI: 10.2337/db13-1256
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 27920125
Title: Structures of human mitofusin 1 provide insight into mitochondrial tethering.
PubMed ID: 27920125
PubMed ID: 28114303
Title: MFN1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion.
PubMed ID: 28114303
DOI: 10.1038/nature21077
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 741
- Mass: 84160
- Checksum: B7BDC22437E30A58
- Sequence:
MAEPVSPLKH FVLAKKAITA IFDQLLEFVT EGSHFVEATY KNPELDRIAT EDDLVEMQGY KDKLSIIGEV LSRRHMKVAF FGRTSSGKSS VINAMLWDKV LPSGIGHITN CFLSVEGTDG DKAYLMTEGS DEKKSVKTVN QLAHALHMDK DLKAGCLVRV FWPKAKCALL RDDLVLVDSP GTDVTTELDS WIDKFCLDAD VFVLVANSES TLMNTEKHFF HKVNERLSKP NIFILNNRWD ASASEPEYME DVRRQHMERC LHFLVEELKV VNALEAQNRI FFVSAKEVLS ARKQKAQGMP ESGVALAEGF HARLQEFQNF EQIFEECISQ SAVKTKFEQH TIRAKQILAT VKNIMDSVNL AAEDKRHYSV EEREDQIDRL DFIRNQMNLL TLDVKKKIKE VTEEVANKVS CAMTDEICRL SVLVDEFCSE FHPNPDVLKI YKSELNKHIE DGMGRNLADR CTDEVNALVL QTQQEIIENL KPLLPAGIQD KLHTLIPCKK FDLSYNLNYH KLCSDFQEDI VFRFSLGWSS LVHRFLGPRN AQRVLLGLSE PIFQLPRSLA STPTAPTTPA TPDNASQEEL MITLVTGLAS VTSRTSMGII IVGGVIWKTI GWKLLSVSLT MYGALYLYER LSWTTHAKER AFKQQFVNYA TEKLRMIVSS TSANCSHQVK QQIATTFARL CQQVDITQKQ LEEEIARLPK EIDQLEKIQN NSKLLRNKAV QLENELENFT KQFLPSSNEE S
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.