Details for: PARVA

Gene ID: 55742

Symbol: PARVA

Ensembl ID: ENSG00000197702

Description: parvin alpha

Associated with

Other Information

Genular Protein ID: 4003400587

Symbol: PARVA_HUMAN

Name: Alpha-parvin

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11171322

Title: Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily.

PubMed ID: 11171322

DOI: 10.1242/jcs.114.3.525

PubMed ID: 11331308

Title: A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading.

PubMed ID: 11331308

DOI: 10.1083/jcb.153.3.585

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15242332

Title: Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes.

PubMed ID: 15242332

DOI: 10.1042/bj20040647

PubMed ID: 11134073

Title: Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion.

PubMed ID: 11134073

DOI: 10.1083/jcb.151.7.1435

PubMed ID: 11722847

Title: Genomic organization and expression profile of the parvin family of focal adhesion proteins in mice and humans.

PubMed ID: 11722847

DOI: 10.1016/s0378-1119(01)00743-0

PubMed ID: 15284246

Title: Distinct roles of two structurally closely related focal adhesion proteins, alpha-parvins and beta-parvins, in regulation of cell morphology and survival.

PubMed ID: 15284246

DOI: 10.1074/jbc.m401563200

PubMed ID: 15817463

Title: Actopaxin interacts with TESK1 to regulate cell spreading on fibronectin.

PubMed ID: 15817463

DOI: 10.1074/jbc.m500752200

PubMed ID: 16860736

Title: CdGAP associates with actopaxin to regulate integrin-dependent changes in cell morphology and motility.

PubMed ID: 16860736

DOI: 10.1016/j.cub.2006.05.057

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20393563

Title: Functional genomic screen for modulators of ciliogenesis and cilium length.

PubMed ID: 20393563

DOI: 10.1038/nature08895

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22441983

Title: LNK (SH2B3) is a key regulator of integrin signaling in endothelial cells and targets alpha-parvin to control cell adhesion and migration.

PubMed ID: 22441983

DOI: 10.1096/fj.11-193383

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 18508764

Title: The structure of alpha-parvin CH2-paxillin LD1 complex reveals a novel modular recognition for focal adhesion assembly.

PubMed ID: 18508764

DOI: 10.1074/jbc.m801270200

PubMed ID: 18940607

Title: Structural analysis of the interactions between paxillin LD motifs and alpha-parvin.

PubMed ID: 18940607

DOI: 10.1016/j.str.2008.08.007

PubMed ID: 20005845

Title: The pseudoactive site of ILK is essential for its binding to alpha-parvin and localization to focal adhesions.

PubMed ID: 20005845

DOI: 10.1016/j.molcel.2009.11.028

Sequence Information:

  • Length: 372
  • Mass: 42244
  • Checksum: F48BB5B1E83F8CEF
  • Sequence:
  • MATSPQKSPS VPKSPTPKSP PSRKKDDSFL GKLGGTLARR KKAKEVSELQ EEGMNAINLP 
    LSPIPFELDP EDTMLEENEV RTMVDPNSRS DPKLQELMKV LIDWINDVLV GERIIVKDLA 
    EDLYDGQVLQ KLFEKLESEK LNVAEVTQSE IAQKQKLQTV LEKINETLKL PPRSIKWNVD 
    SVHAKSLVAI LHLLVALSQY FRAPIRLPDH VSIQVVVVQK REGILQSRQI QEEITGNTEA 
    LSGRHERDAF DTLFDHAPDK LNVVKKTLIT FVNKHLNKLN LEVTELETQF ADGVYLVLLM 
    GLLEGYFVPL HSFFLTPDSF EQKVLNVSFA FELMQDGGLE KPKPRPEDIV NCDLKSTLRV 
    LYNLFTKYRN VE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.