Details for: TMEM30A

Gene ID: 55754

Symbol: TMEM30A

Ensembl ID: ENSG00000112697

Description: transmembrane protein 30A

Associated with

Other Information

Genular Protein ID: 4196493271

Symbol: CC50A_HUMAN

Name: P4-ATPase flippase complex beta subunit TMEM30A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15375526

Title: Identification and characterization of CDC50A, CDC50B and CDC50C genes in silico.

PubMed ID: 15375526

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 20510206

Title: CDC50A plays a key role in the uptake of the anticancer drug perifosine in human carcinoma cells.

PubMed ID: 20510206

DOI: 10.1016/j.bcp.2010.05.017

PubMed ID: 20947505

Title: Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases.

PubMed ID: 20947505

DOI: 10.1074/jbc.m110.139006

PubMed ID: 20961850

Title: CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery.

PubMed ID: 20961850

DOI: 10.1074/jbc.m110.139543

PubMed ID: 21454556

Title: Critical role of the beta-subunit CDC50A in the stable expression, assembly, subcellular localization, and lipid transport activity of the P4-ATPase ATP8A2.

PubMed ID: 21454556

DOI: 10.1074/jbc.m111.229419

PubMed ID: 21914794

Title: ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner.

PubMed ID: 21914794

DOI: 10.1074/jbc.m111.281006

PubMed ID: 21289302

Title: Human TMEM30a promotes uptake of antitumor and bioactive choline phospholipids into mammalian cells.

PubMed ID: 21289302

DOI: 10.4049/jimmunol.1002710

PubMed ID: 25947375

Title: Phospholipid Flippase ATP10A Translocates Phosphatidylcholine and Is Involved in Plasma Membrane Dynamics.

PubMed ID: 25947375

DOI: 10.1074/jbc.m115.655191

PubMed ID: 29799007

Title: Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation.

PubMed ID: 29799007

DOI: 10.1038/s41467-018-04436-w

PubMed ID: 32493773

Title: Crystal structure of a human plasma membrane phospholipid flippase.

PubMed ID: 32493773

DOI: 10.1074/jbc.ra120.014144

PubMed ID: 31416931

Title: Cryo-EM structures capture the transport cycle of the P4-ATPase flippase.

PubMed ID: 31416931

DOI: 10.1126/science.aay3353

Sequence Information:

  • Length: 361
  • Mass: 40684
  • Checksum: 64B3F28C3EB7801B
  • Sequence:
  • MAMNYNAKDE VDGGPPCAPG GTAKTRRPDN TAFKQQRLPA WQPILTAGTV LPIFFIIGLI 
    FIPIGIGIFV TSNNIREIEI DYTGTEPSSP CNKCLSPDVT PCFCTINFTL EKSFEGNVFM 
    YYGLSNFYQN HRRYVKSRDD SQLNGDSSAL LNPSKECEPY RRNEDKPIAP CGAIANSMFN 
    DTLELFLIGN DSYPIPIALK KKGIAWWTDK NVKFRNPPGG DNLEERFKGT TKPVNWLKPV 
    YMLDSDPDNN GFINEDFIVW MRTAALPTFR KLYRLIERKS DLHPTLPAGR YSLNVTYNYP 
    VHYFDGRKRM ILSTISWMGG KNPFLGIAYI AVGSISFLLG VVLLVINHKY RNSSNTADIT 
    I

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.