Details for: PCID2

Gene ID: 55795

Symbol: PCID2

Ensembl ID: ENSG00000126226

Description: PCI domain containing 2

Associated with

  • Cytoplasm
    (GO:0005737)
  • Double-stranded dna binding
    (GO:0003690)
  • Heterochromatin organization
    (GO:0070828)
  • Negative regulation of apoptotic process
    (GO:0043066)
  • Negative regulation of cysteine-type endopeptidase activity
    (GO:2000117)
  • Negative regulation of lymphoid progenitor cell differentiation
    (GO:1905457)
  • Negative regulation of transcription initiation by rna polymerase ii
    (GO:0060633)
  • Nuclear pore nuclear basket
    (GO:0044615)
  • Nucleus
    (GO:0005634)
  • Poly(a)+ mrna export from nucleus
    (GO:0016973)
  • Positive regulation of b cell differentiation
    (GO:0045579)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of mitotic cell cycle spindle assembly checkpoint
    (GO:0090267)
  • Post-transcriptional tethering of rna polymerase ii gene dna at nuclear periphery
    (GO:0000973)
  • Protein binding
    (GO:0005515)
  • Protein transport
    (GO:0015031)
  • Regulation of mrna stability
    (GO:0043488)
  • Rna binding
    (GO:0003723)
  • Spleen development
    (GO:0048536)
  • Transcription elongation by rna polymerase ii
    (GO:0006368)
  • Transcription export complex 2
    (GO:0070390)

Other Information

Genular Protein ID: 3046549495

Symbol: PCID2_HUMAN

Name: PCI domain-containing protein 2

UniProtKB Accession Codes:

Q5JVF3 A6NK09 Q3ZCX1 Q5TC57 Q5TC58 Q9H7K1 Q9HBZ7 Q9NUK6 Q9NVY1 Q9NW44 Q9NWH3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CTD 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 11 EPD 1 Ensembl 7 ExpressionAtlas 1 GO 20 Gene3D 1 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 RefSeq 9 SMART 1 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22307388

Title: Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export.

PubMed ID: 22307388

DOI: 10.1093/nar/gks059

PubMed ID: 23591820

Title: The human TREX-2 complex is stably associated with the nuclear pore basket.

PubMed ID: 23591820

DOI: 10.1242/jcs.118000

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24896180

Title: BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2.

PubMed ID: 24896180

DOI: 10.1038/nature13374

Sequence Information:

  • Length: 399
  • Mass: 46030
  • Checksum: 8D23273361F00E18
  • Sequence:
    • MAHITINQYL QQVYEAIDSR DGASCAELVS FKHPHVANPR LQMASPEEKC QQVLEPPYDE 
MFAAHLRCTY AVGNHDFIEA YKCQTVIVQS FLRAFQAHKE ENWALPVMYA VALDLRVFAN 
NADQQLVKKG KSKVGDMLEK AAELLMSCFR VCASDTRAGI EDSKKWGMLF LVNQLFKIYF 
KINKLHLCKP LIRAIDSSNL KDDYSTAQRV TYKYYVGRKA MFDSDFKQAE EYLSFAFEHC 
HRSSQKNKRM ILIYLLPVKM LLGHMPTVEL LKKYHLMQFA EVTRAVSEGN LLLLHEALAK 
HEAFFIRCGI FLILEKLKII TYRNLFKKVY LLLKTHQLSL DAFLVALKFM QVEDVDIDEV 
QCILANLIYM GHVKGYISHQ HQKLVVSKQN PFPPLSTVC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.