Details for: AXL

Gene ID: 558

Symbol: AXL

Ensembl ID: ENSG00000167601

Description: AXL receptor tyrosine kinase

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 3.06
    Marker Score: 171375
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 2.98
    Marker Score: 1959
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 2.52
    Marker Score: 1367
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 2.48
    Marker Score: 2484
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 2.25
    Marker Score: 935
  • Cell Name: inflammatory cell (CL0009002)
    Fold Change: 2.18
    Marker Score: 939
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 2.18
    Marker Score: 9390
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.17
    Marker Score: 73918
  • Cell Name: fibroblast of connective tissue of prostate (CL1000299)
    Fold Change: 1.98
    Marker Score: 492
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 1.97
    Marker Score: 104379
  • Cell Name: prostate stromal cell (CL0002622)
    Fold Change: 1.96
    Marker Score: 492
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 1.95
    Marker Score: 3804
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 1.94
    Marker Score: 1107
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 1.91
    Marker Score: 1631
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.87
    Marker Score: 2148
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 1.85
    Marker Score: 5832
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.82
    Marker Score: 4451
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.73
    Marker Score: 1651
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 1.62
    Marker Score: 7955
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 1.61
    Marker Score: 582
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 1.6
    Marker Score: 3012
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.58
    Marker Score: 1150
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.58
    Marker Score: 1967
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 1.52
    Marker Score: 3971
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 1.49
    Marker Score: 38074
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.47
    Marker Score: 375
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 168286
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 1.45
    Marker Score: 8627
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.45
    Marker Score: 1444
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 1.45
    Marker Score: 1399
  • Cell Name: pericyte (CL0000669)
    Fold Change: 1.45
    Marker Score: 846
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.39
    Marker Score: 319
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 1.38
    Marker Score: 2508
  • Cell Name: muscle cell (CL0000187)
    Fold Change: 1.37
    Marker Score: 389
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.36
    Marker Score: 15340
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.36
    Marker Score: 352
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 1.3
    Marker Score: 321
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.29
    Marker Score: 642
  • Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
    Fold Change: 1.29
    Marker Score: 290
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 1.28
    Marker Score: 1759
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 1.26
    Marker Score: 405
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 1.24
    Marker Score: 881
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.22
    Marker Score: 1302
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.18
    Marker Score: 25184
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.18
    Marker Score: 2393
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: 1.17
    Marker Score: 343
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.12
    Marker Score: 2161
  • Cell Name: reticular cell (CL0000432)
    Fold Change: 1.08
    Marker Score: 395
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.06
    Marker Score: 1430
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 1.06
    Marker Score: 2740
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 1.06
    Marker Score: 667
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: 1.06
    Marker Score: 1376
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.04
    Marker Score: 251755
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.03
    Marker Score: 18234
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71776
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47999
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 0.98
    Marker Score: 12968
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30404
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.98
    Marker Score: 1183
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.98
    Marker Score: 285
  • Cell Name: eurydendroid cell (CL0000253)
    Fold Change: 0.97
    Marker Score: 397
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.97
    Marker Score: 2132
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.97
    Marker Score: 500
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.97
    Marker Score: 1169
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 0.97
    Marker Score: 635
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.96
    Marker Score: 455
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2410
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 0.94
    Marker Score: 621
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 0.93
    Marker Score: 2179.5
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.92
    Marker Score: 422
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.91
    Marker Score: 3828
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2729
  • Cell Name: interstitial cell of Cajal (CL0002088)
    Fold Change: 0.91
    Marker Score: 314
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.89
    Marker Score: 321
  • Cell Name: bronchial smooth muscle cell (CL0002598)
    Fold Change: 0.89
    Marker Score: 252
  • Cell Name: blood vessel smooth muscle cell (CL0019018)
    Fold Change: 0.89
    Marker Score: 234
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.87
    Marker Score: 4987
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5273
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 0.86
    Marker Score: 1062
  • Cell Name: epithelial cell of glomerular capsule (CL1000450)
    Fold Change: 0.85
    Marker Score: 217
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.83
    Marker Score: 332
  • Cell Name: smooth muscle cell of large intestine (CL1000279)
    Fold Change: 0.83
    Marker Score: 313
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.82
    Marker Score: 480
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.82
    Marker Score: 4932
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.81
    Marker Score: 12617
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.8
    Marker Score: 384
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.8
    Marker Score: 612
  • Cell Name: theca cell (CL0000503)
    Fold Change: 0.8
    Marker Score: 570
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.77
    Marker Score: 1258
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.77
    Marker Score: 699
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 391
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.75
    Marker Score: 3166
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 0.75
    Marker Score: 884
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.74
    Marker Score: 1194
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.74
    Marker Score: 239
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.74
    Marker Score: 822
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: 0.73
    Marker Score: 336
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.72
    Marker Score: 641
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.72
    Marker Score: 228
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.7
    Marker Score: 291

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Other Information

**Key characteristics:** - AXL is a receptor for vascular endothelial growth factor-alpha (VEGF). - It is a transmembrane protein with a cytoplasmic domain that is responsible for binding to VEGF and initiating signaling pathways. - AXL is also involved in cell migration, angiogenesis, and inflammation. **Pathways and functions:** - AXL is a key regulator of blood vessel remodeling and inflammation. - It is expressed in endothelial cells and immune cells, where it mediates the effects of VEGF on cell migration, proliferation, and survival. - It also plays a role in the regulation of myosin heavy chain expression, which is important for muscle contraction. - AXL is involved in the differentiation and survival of natural killer cells. - It is also involved in the regulation of apoptosis and cell migration. **Clinical significance:** - Mutations in the AXL gene have been linked to several human diseases, including cancer, cardiovascular disease, and inflammation. - Inhibition of AXL has been shown to suppress tumor growth and inflammation. - Therefore, AXL is a promising target for cancer immunotherapy. **Additional notes:** - AXL is a highly conserved protein with significant expression in mammals. - It is a member of the receptor tyrosine kinase family of proteins. - AXL is a key regulator of angiogenesis, which is the process by which new blood vessels form.

Genular Protein ID: 3788044498

Symbol: UFO_HUMAN

Name: Tyrosine-protein kinase receptor UFO

UniProtKB Accession Codes:

P30530 Q8N5L2 Q9UD27

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 4 CORUM 1 CPTAC 2 CPTC 1 CTD 1 ChEBI 7 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 DrugCentral 1 EC 1 EMBL 5 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 59 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 4 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 5 PROSITE-ProRule 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 Rhea 3 SAM 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2247464

Title: Putative tyrosine kinases expressed in K-562 human leukemia cells.

PubMed ID: 2247464

DOI: 10.1073/pnas.87.22.8913

PubMed ID: 1656220

Title: AXL, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.

PubMed ID: 1656220

DOI: 10.1128/mcb.11.10.5016-5031.1991

PubMed ID: 1834974

Title: A novel putative tyrosine kinase receptor with oncogenic potential.

PubMed ID: 1834974

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8247543

Title: A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes.

PubMed ID: 8247543

PubMed ID: 7896447

Title: Receptor tyrosine kinases expressed in metastatic colon cancer.

PubMed ID: 7896447

DOI: 10.1002/ijc.2910600611

PubMed ID: 7854420

Title: Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6.

PubMed ID: 7854420

DOI: 10.1038/373623a0

PubMed ID: 8621659

Title: Characterization of Gas6, a member of the superfamily of G domain-containing proteins, as a ligand for Rse and Axl.

PubMed ID: 8621659

DOI: 10.1074/jbc.271.16.9785

PubMed ID: 9178760

Title: Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site.

PubMed ID: 9178760

DOI: 10.1038/sj.onc.1201123

PubMed ID: 10403904

Title: A receptor tyrosine kinase, UFO/Axl, and other genes isolated by a modified differential display PCR are overexpressed in metastatic prostatic carcinoma cell line DU145.

PubMed ID: 10403904

DOI: 10.1046/j.1525-1500.1999.99034.x

PubMed ID: 11484958

Title: Estrogen dependent expression of the receptor tyrosine kinase axl in normal and malignant human breast.

PubMed ID: 11484958

DOI: 10.1023/a:1011126330233

PubMed ID: 12470648

Title: Interaction of Axl receptor tyrosine kinase with C1-TEN, a novel C1 domain-containing protein with homology to tensin.

PubMed ID: 12470648

DOI: 10.1016/s0006-291x(02)02718-3

PubMed ID: 12364394

Title: Acidification prevents endothelial cell apoptosis by Axl activation.

PubMed ID: 12364394

DOI: 10.1161/01.res.0000036753.50601.e9

PubMed ID: 12490074

Title: Expression of receptor-type tyrosine kinase, Axl, and its ligand, Gas6, in pediatric thyroid carcinomas around Chernobyl.

PubMed ID: 12490074

DOI: 10.1089/105072502320908303

PubMed ID: 15958209

Title: Effects of Gas6 and hydrogen peroxide in Axl ubiquitination and downregulation.

PubMed ID: 15958209

DOI: 10.1016/j.bbrc.2005.05.086

PubMed ID: 15507525

Title: Inhibition of vascular endothelial growth factor receptor 2-mediated endothelial cell activation by Axl tyrosine kinase receptor.

PubMed ID: 15507525

DOI: 10.1182/blood-2004-04-1469

PubMed ID: 15733062

Title: Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses.

PubMed ID: 15733062

DOI: 10.1111/j.1538-7836.2005.01186.x

PubMed ID: 17005688

Title: Tyro3 family-mediated cell entry of Ebola and Marburg viruses.

PubMed ID: 17005688

DOI: 10.1128/jvi.01157-06

PubMed ID: 18346204

Title: In brain, Axl recruits Grb2 and the p85 regulatory subunit of PI3 kinase; in vitro mutagenesis defines the requisite binding sites for downstream Akt activation.

PubMed ID: 18346204

DOI: 10.1111/j.1471-4159.2008.05343.x

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18840707

Title: The Axl/Gas6 pathway is required for optimal cytokine signaling during human natural killer cell development.

PubMed ID: 18840707

DOI: 10.1182/blood-2008-05-157073

PubMed ID: 19815557

Title: Cytoplasmic ACK1 interaction with multiple receptor tyrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signaling.

PubMed ID: 19815557

DOI: 10.1074/jbc.m109.072660

PubMed ID: 21501828

Title: The soluble serum protein Gas6 bridges virion envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry.

PubMed ID: 21501828

DOI: 10.1016/j.chom.2011.03.012

PubMed ID: 22156524

Title: Identification of cell surface molecules involved in dystroglycan-independent Lassa virus cell entry.

PubMed ID: 22156524

DOI: 10.1128/jvi.06451-11

PubMed ID: 22673088

Title: Cell surface molecules involved in infection mediated by lymphocytic choriomeningitis virus glycoprotein.

PubMed ID: 22673088

DOI: 10.1292/jvms.12-0176

PubMed ID: 25277499

Title: Phosphatidylserine receptors: enhancers of enveloped virus entry and infection.

PubMed ID: 25277499

DOI: 10.1016/j.virol.2014.09.009

PubMed ID: 28076778

Title: Axl Mediates ZIKA Virus Entry in Human Glial Cells and Modulates Innate Immune Responses.

PubMed ID: 28076778

DOI: 10.1016/j.celrep.2016.12.045

PubMed ID: 29379210

Title: AXL promotes Zika virus infection in astrocytes by antagonizing type I interferon signalling.

PubMed ID: 29379210

DOI: 10.1038/s41564-017-0092-4

PubMed ID: 31311882

Title: Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells.

PubMed ID: 31311882

DOI: 10.1128/mbio.01372-19

PubMed ID: 16362042

Title: Structural basis for Gas6-Axl signalling.

PubMed ID: 16362042

DOI: 10.1038/sj.emboj.7600912

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 894
  • Mass: 98337
  • Checksum: 262D3659218E3202
  • Sequence:
    • MAWRCPRMGR VPLAWCLALC GWACMAPRGT QAEESPFVGN PGNITGARGL TGTLRCQLQV 
QGEPPEVHWL RDGQILELAD STQTQVPLGE DEQDDWIVVS QLRITSLQLS DTGQYQCLVF 
LGHQTFVSQP GYVGLEGLPY FLEEPEDRTV AANTPFNLSC QAQGPPEPVD LLWLQDAVPL 
ATAPGHGPQR SLHVPGLNKT SSFSCEAHNA KGVTTSRTAT ITVLPQQPRN LHLVSRQPTE 
LEVAWTPGLS GIYPLTHCTL QAVLSDDGMG IQAGEPDPPE EPLTSQASVP PHQLRLGSLH 
PHTPYHIRVA CTSSQGPSSW THWLPVETPE GVPLGPPENI SATRNGSQAF VHWQEPRAPL 
QGTLLGYRLA YQGQDTPEVL MDIGLRQEVT LELQGDGSVS NLTVCVAAYT AAGDGPWSLP 
VPLEAWRPGQ AQPVHQLVKE PSTPAFSWPW WYVLLGAVVA AACVLILALF LVHRRKKETR 
YGEVFEPTVE RGELVVRYRV RKSYSRRTTE ATLNSLGISE ELKEKLRDVM VDRHKVALGK 
TLGEGEFGAV MEGQLNQDDS ILKVAVKTMK IAICTRSELE DFLSEAVCMK EFDHPNVMRL 
IGVCFQGSER ESFPAPVVIL PFMKHGDLHS FLLYSRLGDQ PVYLPTQMLV KFMADIASGM 
EYLSTKRFIH RDLAARNCML NENMSVCVAD FGLSKKIYNG DYYRQGRIAK MPVKWIAIES 
LADRVYTSKS DVWSFGVTMW EIATRGQTPY PGVENSEIYD YLRQGNRLKQ PADCLDGLYA 
LMSRCWELNP QDRPSFTELR EDLENTLKAL PPAQEPDEIL YVNMDEGGGY PEPPGAAGGA 
DPPTQPDPKD SCSCLTAAEV HPAGRYVLCP STTPSPAQPA DRGSPAAPGQ EDGA

Genular Protein ID: 3229020786

Symbol: M0R0W6_HUMAN

Name: N/A

UniProtKB Accession Codes:

M0R0W6

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 6 ChiTaRS 1 DNASU 1 EC 1 EMBL 3 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 IntAct 1 InterPro 9 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 1 Rhea 3 SAM 2 SMART 1 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

Sequence Information:

  • Length: 626
  • Mass: 69231
  • Checksum: 66372173936B138F
  • Sequence:
    • MGIQAGEPDP PEEPLTSQAS VPPHQLRLGS LHPHTPYHIR VACTSSQGPS SWTHWLPVET 
PEGVPLGPPE NISATRNGSQ AFVHWQEPRA PLQGTLLGYR LAYQGQDTPE VLMDIGLRQE 
VTLELQGDGS VSNLTVCVAA YTAAGDGPWS LPVPLEAWRP GQAQPVHQLV KEPSTPAFSW 
PWWYVLLGAV VAAACVLILA LFLVHRRKKE TRYGEVFEPT VERGELVVRY RVRKSYSRRT 
TEATLNSLGI SEELKEKLRD VMVDRHKVAL GKTLGEGEFG AVMEGQLNQD DSILKVAVKT 
MKIAICTRSE LEDFLSEAVC MKEFDHPNVM RLIGVCFQGS ERESFPAPVV ILPFMKHGDL 
HSFLLYSRLG DQPVYLPTQM LVKFMADIAS GMEYLSTKRF IHRDLAARNC MLNENMSVCV 
ADFGLSKKIY NGDYYRQGRI AKMPVKWIAI ESLADRVYTS KSDVWSFGVT MWEIATRGQT 
PYPGVENSEI YDYLRQGNRL KQPADCLDGL YALMSRCWEL NPQDRPSFTE LREDLENTLK 
ALPPAQEPDE ILYVNMDEGG GYPEPPGAAG GADPPTQPDP KDSCSCLTAA EVHPAGRYVL 
CPSTTPSPAQ PADRGSPAAP GQEDGA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.