Details for: AXL
Associated with
Other Information
Genular Protein ID: 3788044498
Symbol: UFO_HUMAN
Name: Tyrosine-protein kinase receptor UFO
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2247464
Title: Putative tyrosine kinases expressed in K-562 human leukemia cells.
PubMed ID: 2247464
PubMed ID: 1656220
Title: AXL, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.
PubMed ID: 1656220
PubMed ID: 1834974
Title: A novel putative tyrosine kinase receptor with oncogenic potential.
PubMed ID: 1834974
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8247543
Title: A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes.
PubMed ID: 8247543
PubMed ID: 7896447
Title: Receptor tyrosine kinases expressed in metastatic colon cancer.
PubMed ID: 7896447
PubMed ID: 7854420
Title: Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6.
PubMed ID: 7854420
DOI: 10.1038/373623a0
PubMed ID: 8621659
Title: Characterization of Gas6, a member of the superfamily of G domain-containing proteins, as a ligand for Rse and Axl.
PubMed ID: 8621659
PubMed ID: 9178760
Title: Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site.
PubMed ID: 9178760
PubMed ID: 10403904
Title: A receptor tyrosine kinase, UFO/Axl, and other genes isolated by a modified differential display PCR are overexpressed in metastatic prostatic carcinoma cell line DU145.
PubMed ID: 10403904
PubMed ID: 11484958
Title: Estrogen dependent expression of the receptor tyrosine kinase axl in normal and malignant human breast.
PubMed ID: 11484958
PubMed ID: 12470648
Title: Interaction of Axl receptor tyrosine kinase with C1-TEN, a novel C1 domain-containing protein with homology to tensin.
PubMed ID: 12470648
PubMed ID: 12364394
Title: Acidification prevents endothelial cell apoptosis by Axl activation.
PubMed ID: 12364394
PubMed ID: 12490074
Title: Expression of receptor-type tyrosine kinase, Axl, and its ligand, Gas6, in pediatric thyroid carcinomas around Chernobyl.
PubMed ID: 12490074
PubMed ID: 15958209
Title: Effects of Gas6 and hydrogen peroxide in Axl ubiquitination and downregulation.
PubMed ID: 15958209
PubMed ID: 15507525
Title: Inhibition of vascular endothelial growth factor receptor 2-mediated endothelial cell activation by Axl tyrosine kinase receptor.
PubMed ID: 15507525
PubMed ID: 15733062
Title: Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses.
PubMed ID: 15733062
PubMed ID: 17005688
Title: Tyro3 family-mediated cell entry of Ebola and Marburg viruses.
PubMed ID: 17005688
DOI: 10.1128/jvi.01157-06
PubMed ID: 18346204
Title: In brain, Axl recruits Grb2 and the p85 regulatory subunit of PI3 kinase; in vitro mutagenesis defines the requisite binding sites for downstream Akt activation.
PubMed ID: 18346204
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18840707
Title: The Axl/Gas6 pathway is required for optimal cytokine signaling during human natural killer cell development.
PubMed ID: 18840707
PubMed ID: 19815557
Title: Cytoplasmic ACK1 interaction with multiple receptor tyrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signaling.
PubMed ID: 19815557
PubMed ID: 21501828
Title: The soluble serum protein Gas6 bridges virion envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry.
PubMed ID: 21501828
PubMed ID: 22156524
Title: Identification of cell surface molecules involved in dystroglycan-independent Lassa virus cell entry.
PubMed ID: 22156524
DOI: 10.1128/jvi.06451-11
PubMed ID: 22673088
Title: Cell surface molecules involved in infection mediated by lymphocytic choriomeningitis virus glycoprotein.
PubMed ID: 22673088
DOI: 10.1292/jvms.12-0176
PubMed ID: 25277499
Title: Phosphatidylserine receptors: enhancers of enveloped virus entry and infection.
PubMed ID: 25277499
PubMed ID: 28076778
Title: Axl Mediates ZIKA Virus Entry in Human Glial Cells and Modulates Innate Immune Responses.
PubMed ID: 28076778
PubMed ID: 29379210
Title: AXL promotes Zika virus infection in astrocytes by antagonizing type I interferon signalling.
PubMed ID: 29379210
PubMed ID: 31311882
Title: Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells.
PubMed ID: 31311882
PubMed ID: 16362042
PubMed ID: 17344846
Title: Patterns of somatic mutation in human cancer genomes.
PubMed ID: 17344846
DOI: 10.1038/nature05610
Sequence Information:
- Length: 894
- Mass: 98337
- Checksum: 262D3659218E3202
- Sequence:
MAWRCPRMGR VPLAWCLALC GWACMAPRGT QAEESPFVGN PGNITGARGL TGTLRCQLQV QGEPPEVHWL RDGQILELAD STQTQVPLGE DEQDDWIVVS QLRITSLQLS DTGQYQCLVF LGHQTFVSQP GYVGLEGLPY FLEEPEDRTV AANTPFNLSC QAQGPPEPVD LLWLQDAVPL ATAPGHGPQR SLHVPGLNKT SSFSCEAHNA KGVTTSRTAT ITVLPQQPRN LHLVSRQPTE LEVAWTPGLS GIYPLTHCTL QAVLSDDGMG IQAGEPDPPE EPLTSQASVP PHQLRLGSLH PHTPYHIRVA CTSSQGPSSW THWLPVETPE GVPLGPPENI SATRNGSQAF VHWQEPRAPL QGTLLGYRLA YQGQDTPEVL MDIGLRQEVT LELQGDGSVS NLTVCVAAYT AAGDGPWSLP VPLEAWRPGQ AQPVHQLVKE PSTPAFSWPW WYVLLGAVVA AACVLILALF LVHRRKKETR YGEVFEPTVE RGELVVRYRV RKSYSRRTTE ATLNSLGISE ELKEKLRDVM VDRHKVALGK TLGEGEFGAV MEGQLNQDDS ILKVAVKTMK IAICTRSELE DFLSEAVCMK EFDHPNVMRL IGVCFQGSER ESFPAPVVIL PFMKHGDLHS FLLYSRLGDQ PVYLPTQMLV KFMADIASGM EYLSTKRFIH RDLAARNCML NENMSVCVAD FGLSKKIYNG DYYRQGRIAK MPVKWIAIES LADRVYTSKS DVWSFGVTMW EIATRGQTPY PGVENSEIYD YLRQGNRLKQ PADCLDGLYA LMSRCWELNP QDRPSFTELR EDLENTLKAL PPAQEPDEIL YVNMDEGGGY PEPPGAAGGA DPPTQPDPKD SCSCLTAAEV HPAGRYVLCP STTPSPAQPA DRGSPAAPGQ EDGA
Genular Protein ID: 3229020786
Symbol: M0R0W6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
Sequence Information:
- Length: 626
- Mass: 69231
- Checksum: 66372173936B138F
- Sequence:
MGIQAGEPDP PEEPLTSQAS VPPHQLRLGS LHPHTPYHIR VACTSSQGPS SWTHWLPVET PEGVPLGPPE NISATRNGSQ AFVHWQEPRA PLQGTLLGYR LAYQGQDTPE VLMDIGLRQE VTLELQGDGS VSNLTVCVAA YTAAGDGPWS LPVPLEAWRP GQAQPVHQLV KEPSTPAFSW PWWYVLLGAV VAAACVLILA LFLVHRRKKE TRYGEVFEPT VERGELVVRY RVRKSYSRRT TEATLNSLGI SEELKEKLRD VMVDRHKVAL GKTLGEGEFG AVMEGQLNQD DSILKVAVKT MKIAICTRSE LEDFLSEAVC MKEFDHPNVM RLIGVCFQGS ERESFPAPVV ILPFMKHGDL HSFLLYSRLG DQPVYLPTQM LVKFMADIAS GMEYLSTKRF IHRDLAARNC MLNENMSVCV ADFGLSKKIY NGDYYRQGRI AKMPVKWIAI ESLADRVYTS KSDVWSFGVT MWEIATRGQT PYPGVENSEI YDYLRQGNRL KQPADCLDGL YALMSRCWEL NPQDRPSFTE LREDLENTLK ALPPAQEPDE ILYVNMDEGG GYPEPPGAAG GADPPTQPDP KDSCSCLTAA EVHPAGRYVL CPSTTPSPAQ PADRGSPAAP GQEDGA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.