Details for: EMC3

Gene ID: 55831

Symbol: EMC3

Ensembl ID: ENSG00000125037

Description: ER membrane protein complex subunit 3

Associated with

Other Information

Genular Protein ID: 3897758978

Symbol: EMC3_HUMAN

Name: ER membrane protein complex subunit 3

UniProtKB Accession Codes:

Q9P0I2 B2R4Z9 Q53GH8 Q6ZMC2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 ComplexPortal 2 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 EMDB 6 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 5 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 11 PDBsum 6 PIRSF 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SignaLink 1 TCDB 1 TopDownProteomics 2 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10931946

Title: Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.

PubMed ID: 10931946

DOI: 10.1073/pnas.160270997

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22119785

Title: Defining human ERAD networks through an integrative mapping strategy.

PubMed ID: 22119785

DOI: 10.1038/ncb2383

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 30415835

Title: EMC Is Required to Initiate Accurate Membrane Protein Topogenesis.

PubMed ID: 30415835

DOI: 10.1016/j.cell.2018.10.009

PubMed ID: 29809151

Title: The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins.

PubMed ID: 29809151

DOI: 10.7554/elife.37018

PubMed ID: 29242231

Title: The ER membrane protein complex is a transmembrane domain insertase.

PubMed ID: 29242231

DOI: 10.1126/science.aao3099

PubMed ID: 32459176

Title: The architecture of EMC reveals a path for membrane protein insertion.

PubMed ID: 32459176

DOI: 10.7554/elife.57887

PubMed ID: 32439656

Title: Structural basis for membrane insertion by the human ER membrane protein complex.

PubMed ID: 32439656

DOI: 10.1126/science.abb5008

Sequence Information:

  • Length: 261
  • Mass: 29952
  • Checksum: 0FB279E54D6C1FCC
  • Sequence:
    • MAGPELLLDS NIRLWVVLPI VIITFFVGMI RHYVSILLQS DKKLTQEQVS DSQVLIRSRV 
LRENGKYIPK QSFLTRKYYF NNPEDGFFKK TKRKVVPPSP MTDPTMLTDM MKGNVTNVLP 
MILIGGWINM TFSGFVTTKV PFPLTLRFKP MLQQGIELLT LDASWVSSAS WYFLNVFGLR 
SIYSLILGQD NAADQSRMMQ EQMTGAAMAM PADTNKAFKT EWEALELTDH QWALDDVEEE 
LMAKDLHFEG MFKKELQTSI F

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.