CENPN | ENSG00000166451 | NCBI 55839

Details for: CENPN

Gene ID: 55839

Symbol: CENPN

Ensembl ID: ENSG00000166451

Description: centromere protein N

Associated with

Amplification of signal from the kinetochores
(R-HSA-141424)
Amplification of signal from unattached kinetochores via a mad2 inhibitory signal
(R-HSA-141444)
Cell cycle
(R-HSA-1640170)
Cell cycle, mitotic
(R-HSA-69278)
Cell cycle checkpoints
(R-HSA-69620)
Chromosome maintenance
(R-HSA-73886)
Deposition of new cenpa-containing nucleosomes at the centromere
(R-HSA-606279)
Eml4 and nudc in mitotic spindle formation
(R-HSA-9648025)
Mitotic anaphase
(R-HSA-68882)
Mitotic metaphase and anaphase
(R-HSA-2555396)
Mitotic prometaphase
(R-HSA-68877)
Mitotic spindle checkpoint
(R-HSA-69618)
M phase
(R-HSA-68886)
Nucleosome assembly
(R-HSA-774815)
Resolution of sister chromatid cohesion
(R-HSA-2500257)
Rho gtpase effectors
(R-HSA-195258)
Rho gtpases activate formins
(R-HSA-5663220)
Separation of sister chromatids
(R-HSA-2467813)
Signaling by rho gtpases
(R-HSA-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Signal transduction
(R-HSA-162582)
Cenp-a containing chromatin assembly
(GO:0034080)
Chromosome segregation
(GO:0007059)
Cytosol
(GO:0005829)
Inner kinetochore
(GO:0000939)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)

Other Information

Proteins

Centromere protein N

Genular Protein ID: 2294105076

Symbol: CENPN_HUMAN

Name: Centromere protein N

UniProtKB Accession Codes:

Q96H22 A8MZE6 B3KN53 B4DJD1 B4DPY7 C9JJM5 D3DUK8 E7ES30 E7ETS3 Q9NZ83

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16716197

Title: Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells.

PubMed ID: 16716197

DOI: 10.1111/j.1365-2443.2006.00969.x

PubMed ID: 16622420

Title: The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.

PubMed ID: 16622420

DOI: 10.1038/ncb1396

PubMed ID: 16622419

Title: The human CENP-A centromeric nucleosome-associated complex.

PubMed ID: 16622419

DOI: 10.1038/ncb1397

PubMed ID: 18007590

Title: The CENP-A NAC/CAD kinetochore complex controls chromosome congression and spindle bipolarity.

PubMed ID: 18007590

DOI: 10.1038/sj.emboj.7601927

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19543270

Title: Centromere assembly requires the direct recognition of CENP-A nucleosomes by CENP-N.

PubMed ID: 19543270

DOI: 10.1038/ncb1899

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 27499292

Title: The flexible ends of CENP-A nucleosome are required for mitotic fidelity.

PubMed ID: 27499292

DOI: 10.1016/j.molcel.2016.06.023

Sequence Information:

Length: 339
Mass: 39555
Checksum: 7A0D3326032DE99B
Sequence:

MDETVAEFIK RTILKIPMNE LTTILKAWDF LSENQLQTVN FRQRKESVVQ HLIHLCEEKR 
ASISDAALLD IIYMQFHQHQ KVWEVFQMSK GPGEDVDLFD MKQFKNSFKK ILQRALKNVT 
VSFRETEENA VWIRIAWGTQ YTKPNQYKPT YVVYYSQTPY AFTSSSMLRR NTPLLGQALT 
IASKHHQIVK MDLRSRYLDS LKAIVFKQYN QTFETHNSTT PLQERSLGLD INMDSRIIHE 
NIVEKERVQR ITQETFGDYP QPQLEFAQYK LETKFKSGLN GSILAEREEP LRCLIKFSSP 
HLLEALKSLA PAGIADAPLS PLLTCIPNKR MNYFKIRDK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CENPN

Associated with

Other Information

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The sequence and analysis of duplication-rich human chromosome 16. PubMed ID: 15616553

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. PubMed ID: 17081983

Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells. PubMed ID: 16716197

The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. PubMed ID: 16622420

The human CENP-A centromeric nucleosome-associated complex. PubMed ID: 16622419

The CENP-A NAC/CAD kinetochore complex controls chromosome congression and spindle bipolarity. PubMed ID: 18007590

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. PubMed ID: 18691976

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Centromere assembly requires the direct recognition of CENP-A nucleosomes by CENP-N. PubMed ID: 19543270

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

The flexible ends of CENP-A nucleosome are required for mitotic fidelity. PubMed ID: 27499292