NKRF | ENSG00000186416 | NCBI 55922

Details for: NKRF

Gene ID: 55922

Symbol: NKRF

Ensembl ID: ENSG00000186416

Description: NFKB repressing factor

Associated with

Atpase activator activity
(GO:0001671)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Negative regulation of dna-templated transcription
(GO:0045892)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Rna binding
(GO:0003723)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)

Other Information

Proteins

NF-kappa-B-repressing factor

Genular Protein ID: 3611841007

Symbol: NKRF_HUMAN

Name: NF-kappa-B-repressing factor

UniProtKB Accession Codes:

O15226 G3V1N1 Q4VC41 Q9UJ91

Database IDs:

Citations:

PubMed ID: 10562553

Title: Constitutive silencing of IFN-beta promoter is mediated by NRF (NF-kB-repressing factor), a nuclear inhibitor of NF-kB.

PubMed ID: 10562553

DOI: 10.1093/emboj/18.22.6415

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9224902

Title: Identification of a new member (ZNF183) of the Ring finger gene family in Xq24-25.

PubMed ID: 9224902

DOI: 10.1016/s0378-1119(97)00108-x

PubMed ID: 12381793

Title: Identification of a negative response element in the human inducible nitric-oxide synthase (hiNOS) promoter: the role of NF-kappa B-repressing factor (NRF) in basal repression of the hiNOS gene.

PubMed ID: 12381793

DOI: 10.1073/pnas.212306199

PubMed ID: 12429849

Title: Functional proteomic analysis of human nucleolus.

PubMed ID: 12429849

DOI: 10.1091/mbc.e02-05-0271

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24462208

Title: PAXT-1 promotes XRN2 activity by stabilizing it through a conserved domain.

PubMed ID: 24462208

DOI: 10.1016/j.molcel.2014.01.001

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 32179686

Title: Structural basis for DEAH-helicase activation by G-patch proteins.

PubMed ID: 32179686

DOI: 10.1073/pnas.1913880117

Sequence Information:

Length: 690
Mass: 77673
Checksum: 3067A52671A7AE8F
Sequence:

MEKILQMAEG IDIGEMPSYD LVLSKPSKGQ KRHLSTCDGQ NPPKKQAGSK FHARPRFEPV 
HFVASSSKDE RQEDPYGPQT KEVNEQTHFA SMPRDIYQDY TQDSFSIQDG NSQYCDSSGF 
ILTKDQPVTA NMYFDSGNPA PSTTSQQANS QSTPEPSPSQ TFPESVVAEK QYFIEKLTAT 
IWKNLSNPEM TSGSDKINYT YMLTRCIQAC KTNPEYIYAP LKEIPPADIP KNKKLLTDGY 
ACEVRCQNIY LTTGYAGSKN GSRDRATELA VKLLQKRIEV RVVRRKFKHT FGEDLVVCQI 
GMSSYEFPPA LKPPEDLVVL GKDASGQPIF NASAKHWTNF VITENANDAI GILNNSASFN 
KMSIEYKYEM MPNRTWRCRV FLQDHCLAEG YGTKKTSKHA AADEALKILQ KTQPTYPSVK 
SSQCHTGSSP RGSGKKKDIK DLVVYENSSN PVCTLNDTAQ FNRMTVEYVY ERMTGLRWKC 
KVILESEVIA EAVGVKKTVK YEAAGEAVKT LKKTQPTVIN NLKKGAVEDV ISRNEIQGRS 
AEEAYKQQIK EDNIGNQLLR KMGWTGGGLG KSGEGIREPI SVKEQHKREG LGLDVERVNK 
IAKRDIEQII RNYARSESHT DLTFSRELTN DERKQIHQIA QKYGLKSKSH GVGHDRYLVV 
GRKRRKEDLL DQLKQEGQVG HYELVMPQAN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: NKRF

Associated with

Other Information

Constitutive silencing of IFN-beta promoter is mediated by NRF (NF-kB-repressing factor), a nuclear inhibitor of NF-kB. PubMed ID: 10562553

The DNA sequence of the human X chromosome. PubMed ID: 15772651

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification of a new member (ZNF183) of the Ring finger gene family in Xq24-25. PubMed ID: 9224902

Identification of a negative response element in the human inducible nitric-oxide synthase (hiNOS) promoter: the role of NF-kappa B-repressing factor (NRF) in basal repression of the hiNOS gene. PubMed ID: 12381793

Functional proteomic analysis of human nucleolus. PubMed ID: 12429849

Initial characterization of the human central proteome. PubMed ID: 21269460

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

PAXT-1 promotes XRN2 activity by stabilizing it through a conserved domain. PubMed ID: 24462208

Uncovering global SUMOylation signaling networks in a site-specific manner. PubMed ID: 25218447

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. PubMed ID: 28112733

Structural basis for DEAH-helicase activation by G-patch proteins. PubMed ID: 32179686