Details for: Hes6

Gene ID: 55927

Symbol: Hes6

Ensembl ID: ENSMUSG00000067071

Description: hairy and enhancer of split 6

Associated with

  • Anterior/posterior pattern specification
    (GO:0009952)
  • Cell differentiation
    (GO:0030154)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Multicellular organism development
    (GO:0007275)
  • Negative regulation of dna-binding transcription factor activity
    (GO:0043433)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nervous system development
    (GO:0007399)
  • Nucleus
    (GO:0005634)
  • Protein dimerization activity
    (GO:0046983)
  • Protein heterodimerization activity
    (GO:0046982)
  • Protein homodimerization activity
    (GO:0042803)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of neurogenesis
    (GO:0050767)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii-specific dna-binding transcription factor binding
    (GO:0061629)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Transcription regulator complex
    (GO:0005667)

Other Information

Genular Protein ID: 1905957966

Symbol: HES6_MOUSE

Name: Transcription cofactor HES-6

UniProtKB Accession Codes:

Q9JHE6 Q3U2D7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 11 Ensembl 1 GO 18 Gene3D 2 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PROSITE-ProRule 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 10851137

Title: The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation.

PubMed ID: 10851137

DOI: 10.1242/dev.127.13.2933

PubMed ID: 10906477

Title: Expression of hes6, a new member of the Hairy/Enhancer-of-split family, in mouse development.

PubMed ID: 10906477

DOI: 10.1016/s0925-4773(00)00348-8

PubMed ID: 11044617

Title: Expression of mouse HES-6, a new member of the Hairy/Enhancer of split family of bHLH transcription factors.

PubMed ID: 11044617

DOI: 10.1016/s0925-4773(00)00443-3

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 224
  • Mass: 24454
  • Checksum: F5160A69D913DBE2
  • Sequence:
    • MAPSQAPSRD RAGQEDEDRW EARGDRKARK PLVEKKRRAR INESLQELRL LLAGTEVQAK 
LENAEVLELT VRRVQGALRG RAREREQLQA EASERFAAGY IQCMHEVHTF VSTCQAIDAT 
VSAELLNHLL ESMPLREGSS FQDLLGDSLA GLPGGSGRSS WPPGGSPESP LSSPPGPGDD 
LCSDLEEIPE AELNRVPAEG PDLVSTSLGS LTAARRAQSV WRPW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.