Details for: Eif3d

Gene ID: 55944

Symbol: Eif3d

Ensembl ID: ENSMUSG00000016554

Description: eukaryotic translation initiation factor 3, subunit D

Associated with

  • Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
    (R-MMU-72662)
  • Cap-dependent translation initiation
    (R-MMU-72737)
  • Eukaryotic translation initiation
    (R-MMU-72613)
  • Formation of a pool of free 40s subunits
    (R-MMU-72689)
  • Formation of the ternary complex, and subsequently, the 43s complex
    (R-MMU-72695)
  • Gtp hydrolysis and joining of the 60s ribosomal subunit
    (R-MMU-72706)
  • L13a-mediated translational silencing of ceruloplasmin expression
    (R-MMU-156827)
  • Metabolism of proteins
    (R-MMU-392499)
  • Ribosomal scanning and start codon recognition
    (R-MMU-72702)
  • Translation initiation complex formation
    (R-MMU-72649)
  • Cap-dependent translational initiation
    (GO:0002191)
  • Cytoplasm
    (GO:0005737)
  • Eukaryotic translation initiation factor 3 complex
    (GO:0005852)
  • Eukaryotic translation initiation factor 3 complex, eif3m
    (GO:0071541)
  • Formation of cytoplasmic translation initiation complex
    (GO:0001732)
  • Ires-dependent viral translational initiation
    (GO:0075522)
  • Mrna cap binding
    (GO:0098808)
  • Positive regulation of mrna binding
    (GO:1902416)
  • Positive regulation of translation
    (GO:0045727)
  • Rna binding
    (GO:0003723)
  • Synapse
    (GO:0045202)
  • Translation
    (GO:0006412)
  • Translational initiation
    (GO:0006413)
  • Translation initiation factor activity
    (GO:0003743)
  • Viral translational termination-reinitiation
    (GO:0075525)

Other Information

Genular Protein ID: 125208062

Symbol: EIF3D_MOUSE

Name: eIF3 p66

UniProtKB Accession Codes:

O70194 Q8BLH0 Q8BWW1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 6 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 14 GeneTree 1 Genevisible 1 GlyGen 1 HAMAP 1 HAMAP-Rule 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MGI 1 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRO 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 6 RefSeq 2 SAM 1 SMR 1 STRING 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17581632

Title: Reconstitution reveals the functional core of mammalian eIF3.

PubMed ID: 17581632

DOI: 10.1038/sj.emboj.7601765

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

  • Length: 548
  • Mass: 63989
  • Checksum: C23CA1743270DECD
  • Sequence:
    • MAKFMTPVIQ DNPSGWGPCA VPEQFRDMPY QPFSKGDRLG KVADWTGATY QDKRYTNKYS 
SQFGGGSQYA YFHEEDETSF QLVDTARTQK TAYQRNRMRF AQRNLRRDKD RRNMVQFNLQ 
TLPKSAKQKE RERIRLQKKF QKQFGVRQKW DQKSQKPRDS SVEVRSDWEV KEEMDFPQLM 
KMRYLEVSEP QDIECCGALE YYDKAFDRIT TRSEKPLRSI KRIFHTVTTT DDPVIRKLAK 
TQGNVFATDA ILATLMSCTR SVYSWDIVVQ RVGSKLFFDK RDNSDFDLLT VSETANEPPQ 
DEGNSFNSPR NLAMEATYIN HNFSQQCLRM GRERYNFPNP NPFVEDDMDK NEIASVAYRY 
RRWKLGDDID LIVRCEHDGV MTGANGEVSF INIKTLNEWD SRHCNGVDWR QKLDSQRGAV 
IATELKNNSY KLARWTCCAL LAGSEYLKLG YVSRYHVKDS SRHVILGTQQ FKPNEFASQI 
NLSVENAWGI LRCVIDICMK LEEGKYLILK DPNKQVIRVY SLPDGTFSSE EDEEDEEEEE 
EEEEEEET

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.