Sfn | ENSMUSG00000047281 | NCBI 55948

Details for: Sfn

Gene ID: 55948

Symbol: Sfn

Ensembl ID: ENSMUSG00000047281

Description: stratifin

Associated with

Activation of bad and translocation to mitochondria
(R-MMU-111447)
Activation of bh3-only proteins
(R-MMU-114452)
Apoptosis
(R-MMU-109581)
Cell cycle
(R-MMU-1640170)
Cell cycle checkpoints
(R-MMU-69620)
Chk1/chk2(cds1) mediated inactivation of cyclin b:cdk1 complex
(R-MMU-75035)
Foxo-mediated transcription
(R-MMU-9614085)
G2/m checkpoints
(R-MMU-69481)
G2/m dna damage checkpoint
(R-MMU-69473)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Intrinsic pathway for apoptosis
(R-MMU-109606)
Programmed cell death
(R-MMU-5357801)
Regulation of localization of foxo transcription factors
(R-MMU-9614399)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate pkns
(R-MMU-5625740)
Rna polymerase ii transcription
(R-MMU-73857)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Tp53 regulates metabolic genes
(R-MMU-5628897)
Tp53 regulates transcription of cell cycle genes
(R-MMU-6791312)
Tp53 regulates transcription of genes involved in g2 cell cycle arrest
(R-MMU-6804114)
Transcriptional regulation by tp53
(R-MMU-3700989)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Establishment of skin barrier
(GO:0061436)
Extracellular region
(GO:0005576)
Identical protein binding
(GO:0042802)
Intrinsic apoptotic signaling pathway in response to dna damage
(GO:0008630)
Keratinization
(GO:0031424)
Keratinocyte development
(GO:0003334)
Keratinocyte differentiation
(GO:0030216)
Keratinocyte proliferation
(GO:0043616)
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0043154)
Negative regulation of keratinocyte proliferation
(GO:0010839)
Negative regulation of stem cell proliferation
(GO:2000647)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleus
(GO:0005634)
Phosphoprotein binding
(GO:0051219)
Positive regulation of cell growth
(GO:0030307)
Positive regulation of epidermal cell differentiation
(GO:0045606)
Positive regulation of protein export from nucleus
(GO:0046827)
Protein binding
(GO:0005515)
Protein export from nucleus
(GO:0006611)
Protein kinase a signaling
(GO:0010737)
Protein kinase binding
(GO:0019901)
Regulation of cell cycle
(GO:0051726)
Regulation of cyclin-dependent protein serine/threonine kinase activity
(GO:0000079)
Regulation of epidermal cell division
(GO:0010482)
Release of cytochrome c from mitochondria
(GO:0001836)
Signal transduction
(GO:0007165)
Skin development
(GO:0043588)
Stem cell proliferation
(GO:0072089)

Other Information

Proteins

14-3-3 protein sigma

Genular Protein ID: 520583992

Symbol: 1433S_MOUSE

Name: 14-3-3 protein sigma

UniProtKB Accession Codes:

O70456 Q3TEZ1

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 16710422

Title: A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth.

PubMed ID: 16710422

DOI: 10.1038/nature04659

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20478393

Title: SLy2 targets the nuclear SAP30/HDAC1 complex.

PubMed ID: 20478393

DOI: 10.1016/j.biocel.2010.05.004

PubMed ID: 26047703

Title: Suppression of death-associated protein kinase 2 by interaction with 14-3-3 proteins.

PubMed ID: 26047703

DOI: 10.1016/j.bbrc.2015.05.105

Sequence Information:

Length: 248
Mass: 27706
Checksum: C1C40905824B3F48
Sequence:

MERASLIQKA KLAEQAERYE DMAAFMKSAV EKGEELSCEE RNLLSVAYKN VVGGQRAAWR 
VLSSIEQKSN EEGSEEKGPE VKEYREKVET ELRGVCDTVL GLLDSHLIKG AGDAESRVFY 
LKMKGDYYRY LAEVATGDDK KRIIDSARSA YQEAMDISKK EMPPTNPIRL GLALNFSVFH 
YEIANSPEEA ISLAKTTFDE AMADLHTLSE DSYKDSTLIM QLLRDNLTLW TADSAGEEGG 
EAPEEPQS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Sfn

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth. PubMed ID: 16710422

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SLy2 targets the nuclear SAP30/HDAC1 complex. PubMed ID: 20478393