Panx1 | ENSMUSG00000031934 | NCBI 55991

Details for: Panx1

Gene ID: 55991

Symbol: Panx1

Ensembl ID: ENSMUSG00000031934

Description: pannexin 1

Associated with

Electric transmission across gap junctions
(R-MMU-112303)
Immune system
(R-MMU-168256)
Inflammasomes
(R-MMU-622312)
Innate immune system
(R-MMU-168249)
Neuronal system
(R-MMU-112316)
Nucleotide-binding domain, leucine rich repeat containing receptor (nlr) signaling pathways
(R-MMU-168643)
The nlrp3 inflammasome
(R-MMU-844456)
Transmission across electrical synapses
(R-MMU-112307)
Actin binding
(GO:0003779)
Actin filament binding
(GO:0051015)
Anchoring junction
(GO:0070161)
Bleb
(GO:0032059)
Calcium channel activity
(GO:0005262)
Calcium ion transmembrane transport
(GO:0070588)
Calcium ion transport
(GO:0006816)
Cell-cell signaling
(GO:0007267)
Channel activity
(GO:0015267)
Endoplasmic reticulum
(GO:0005783)
Gap junction
(GO:0005921)
Gap junction channel activity
(GO:0005243)
Identical protein binding
(GO:0042802)
Interleukin-1 alpha production
(GO:0032610)
Interleukin-1 beta production
(GO:0032611)
Leak channel activity
(GO:0022840)
Macrophage cytokine production
(GO:0010934)
Membrane
(GO:0016020)
Monoatomic cation transport
(GO:0006812)
Monoatomic ion transmembrane transport
(GO:0034220)
Monoatomic ion transport
(GO:0006811)
Plasma membrane
(GO:0005886)
Positive regulation of interleukin-1 alpha production
(GO:0032730)
Positive regulation of interleukin-1 beta production
(GO:0032731)
Positive regulation of interleukin-1 production
(GO:0032732)
Positive regulation of macrophage cytokine production
(GO:0060907)
Protease binding
(GO:0002020)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Response to atp
(GO:0033198)
Response to ischemia
(GO:0002931)
Scaffold protein binding
(GO:0097110)
Signaling receptor binding
(GO:0005102)
Structural molecule activity
(GO:0005198)
Transmembrane transporter binding
(GO:0044325)
Wide pore channel activity
(GO:0022829)

Other Information

Proteins

Pannexin-1

Genular Protein ID: 265950425

Symbol: PANX1_MOUSE

Name: Pannexin-1

UniProtKB Accession Codes:

Q9JIP4 Q5RL18 Q9CXS7

Database IDs:

Citations:

PubMed ID: 10898987

Title: A ubiquitous family of putative gap junction molecules.

PubMed ID: 10898987

DOI: 10.1016/s0960-9822(00)00576-5

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17925379

Title: Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins.

PubMed ID: 17925379

DOI: 10.1242/jcs.009514

PubMed ID: 23033481

Title: S-nitrosylation inhibits pannexin 1 channel function.

PubMed ID: 23033481

DOI: 10.1074/jbc.m112.397976

Sequence Information:

Length: 426
Mass: 48167
Checksum: 86AF6167C5D39565
Sequence:

MAIAHLATEY VFSDFLLKEP TEPKFKGLRL ELAVDKMVTC IAVGLPLLLI SLAFAQEISI 
GTQISCFSPS SFSWRQAAFV DSYCWAAVQQ KSSLQSESGN LPLWLHKFFP YILLLFAILL 
YLPALFWRFS AAPHLCSDLK FIMEELDKVY NRAIKAAKSA RDLDLRDGPG PPGVTENVGQ 
SLWEISESHF KYPIVEQYLK TKKNSSHLIM KYISCRLVTF VVILLACIYL SYYFSLSSLS 
DEFLCSIKSG VLKNDSTIPD RFQCKLIAVG IFQLLSLINL IVYALLIPVV VYTFFIPFRQ 
KTDILKVYEI LPTFDVLHFK SEGYNDLSLY NLFLEENISE LKSYKCLKVL ENIKSNGQGI 
DPMLLLTNLG MIKMDIIDGK IPTSLQTKGE DQGSQRVEFK DLDLSSEAAA NNGEKNSRQR 
LLNPSC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Panx1

Associated with

Other Information

A ubiquitous family of putative gap junction molecules. PubMed ID: 10898987

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334