Details for: Samhd1

Gene ID: 56045

Symbol: Samhd1

Ensembl ID: ENSMUSG00000027639

Description: SAM domain and HD domain, 1

Associated with

Other Information

Genular Protein ID: 2976057856

Symbol: SAMH1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7884320

Title: Cloning and characterization of a novel cDNA that is IFN-gamma-induced in mouse peritoneal macrophages and encodes a putative GTP-binding protein.

PubMed ID: 7884320

DOI: 10.1002/jlb.57.3.477

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 19525956

Title: Mutations involved in Aicardi-Goutieres syndrome implicate SAMHD1 as regulator of the innate immune response.

PubMed ID: 19525956

DOI: 10.1038/ng.373

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23972988

Title: Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response.

PubMed ID: 23972988

DOI: 10.1016/j.celrep.2013.07.037

PubMed ID: 23872947

Title: SAMHD1-dependent retroviral control and escape in mice.

PubMed ID: 23872947

DOI: 10.1038/emboj.2013.163

PubMed ID: 26667483

Title: Phosphorylation of murine SAMHD1 regulates its antiretroviral activity.

PubMed ID: 26667483

DOI: 10.1186/s12977-015-0229-6

PubMed ID: 29669924

Title: SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation.

PubMed ID: 29669924

DOI: 10.1073/pnas.1719771115

PubMed ID: 31548683

Title: A viral kinase counteracts in vivo restriction of murine cytomegalovirus by SAMHD1.

PubMed ID: 31548683

DOI: 10.1038/s41564-019-0529-z

PubMed ID: 29379009

Title: The SAM domain of mouse SAMHD1 is critical for its activation and regulation.

PubMed ID: 29379009

DOI: 10.1038/s41467-017-02783-8

Sequence Information:

  • Length: 658
  • Mass: 75893
  • Checksum: 8ED07CE9EB6239D6
  • Sequence:
  • MDSLLGCGVS AAAREPVPRY LTSQPRVSEV AMQSAPLEQP AKRPRCDGSP RTPPSTPPAT 
    ANLSADDDFQ NTDLRTWEPE DVCSFLENRG FREKKVLDIF RDNKIAGSFL PFLDEDRLED 
    LGVSSLEERK KMIECIQQLS QSRIDLMKVF NDPIHGHIEF HPLLIRIIDT PQFQRLRYIK 
    QLGGGYYVFP GASHNRFEHS LGVGYLAGCL VRALAEKQPE LQISERDILC VQIAGLCHDL 
    GHGPFSHMFD GRFIPRARPE KKWKHEQGSI EMFEHLVNSN ELKLVMKNYG LVPEEDITFI 
    KEQIMGPPIT PVKDSLWPYK GRPATKSFLY EIVSNKRNGI DVDKWDYFAR DCHHLGIQNN 
    FDYKRFIKFA RICEVEYKVK EDKTYIRKVK HICSREKEVG NLYDMFHTRN CLHRRAYQHK 
    ISNLIDIMIT DAFLKADPYV EITGTAGKKF RISTAIDDME AFTKLTDNIF LEVLHSTDPQ 
    LSEAQSILRN IECRNLYKYL GETQPKREKI RKEEYERLPQ EVAKAKPEKA PDVELKAEDF 
    IVDVINVDYG MEDKNPIDRV HFYCKSNSKQ AVRINKEQVS QLLPEKFAEQ LIRVYCKKKD 
    GKSLDAAGKH FVQWCALRDF TKPQDGDIIA PLITPLKWNN KTSSCLQEVS KVKTCLKF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.