NSMCE3 | ENSG00000185115 | NCBI 56160

Details for: NSMCE3

Gene ID: 56160

Symbol: NSMCE3

Ensembl ID: ENSG00000185115

Description: NSE3 homolog, SMC5-SMC6 complex component

Associated with

Metabolism of proteins
(R-HSA-392499)
Post-translational protein modification
(R-HSA-597592)
Sumo e3 ligases sumoylate target proteins
(R-HSA-3108232)
Sumoylation
(R-HSA-2990846)
Sumoylation of dna damage response and repair proteins
(R-HSA-3108214)
Cellular response to hydroxyurea
(GO:0072711)
Cellular response to radiation
(GO:0071478)
Cellular response to uv
(GO:0034644)
Chromatin looping
(GO:0140588)
Chromosome, telomeric region
(GO:0000781)
Cytoplasm
(GO:0005737)
Dna repair
(GO:0006281)
Double-strand break repair via homologous recombination
(GO:0000724)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of protein ubiquitination
(GO:0031398)
Protein binding
(GO:0005515)
Protein dimerization activity
(GO:0046983)
Protein sumoylation
(GO:0016925)
Regulation of telomere maintenance
(GO:0032204)
Smc5-smc6 complex
(GO:0030915)

Other Information

Proteins

Non-structural maintenance of chromosomes element 3 homolog

Genular Protein ID: 2732479667

Symbol: NSE3_HUMAN

Name: Non-structural maintenance of chromosomes element 3 homolog

UniProtKB Accession Codes:

Q96MG7 Q8IW16 Q8TEI6 Q9H214

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11782285

Title: A necdin/MAGE-like gene in the chromosome 15 autism susceptibility region: expression, imprinting, and mapping of the human and mouse orthologues.

PubMed ID: 11782285

DOI: 10.1186/1471-2156-2-22

PubMed ID: 18086888

Title: Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complex.

PubMed ID: 18086888

DOI: 10.1128/mcb.00767-07

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21364888

Title: Interactions between the Nse3 and Nse4 components of the SMC5-6 complex identify evolutionarily conserved interactions between MAGE and EID Families.

PubMed ID: 21364888

DOI: 10.1371/journal.pone.0017270

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 20864041

Title: MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases.

PubMed ID: 20864041

DOI: 10.1016/j.molcel.2010.08.029

PubMed ID: 27427983

Title: Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease.

PubMed ID: 27427983

DOI: 10.1172/jci82890

Sequence Information:

Length: 304
Mass: 34308
Checksum: C00E2FB2D2CCED7B
Sequence:

MLQKPRNRGR SGGQAERDRD WSHSGNPGAS RAGEDARVLR DGFAEEAPST SRGPGGSQGS 
QGPSPQGARR AQAAPAVGPR SQKQLELKVS ELVQFLLIKD QKKIPIKRAD ILKHVIGDYK 
DIFPDLFKRA AERLQYVFGY KLVELEPKSN TYILINTLEP VEEDAEMRGD QGTPTTGLLM 
IVLGLIFMKG NTIKETEAWD FLRRLGVYPT KKHLIFGDPK KLITEDFVRQ RYLEYRRIPH 
TDPVDYEFQW GPRTNLETSK MKVLKFVAKV HNQDPKDWPA QYCEALADEE NRARPQPSGP 
APSS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: NSMCE3

Associated with

Other Information

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A necdin/MAGE-like gene in the chromosome 15 autism susceptibility region: expression, imprinting, and mapping of the human and mouse orthologues. PubMed ID: 11782285

Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complex. PubMed ID: 18086888

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Initial characterization of the human central proteome. PubMed ID: 21269460

Interactions between the Nse3 and Nse4 components of the SMC5-6 complex identify evolutionarily conserved interactions between MAGE and EID Families. PubMed ID: 21364888

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases. PubMed ID: 20864041

Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease. PubMed ID: 27427983