Details for: ANKH

Gene ID: 56172

Symbol: ANKH

Ensembl ID: ENSG00000154122

Description: ANKH inorganic pyrophosphate transport regulator

Associated with

Other Information

Genular Protein ID: 1723836422

Symbol: ANKH_HUMAN

Name: Progressive ankylosis protein homolog

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10894769

Title: Role of the mouse ank gene in control of tissue calcification and arthritis.

PubMed ID: 10894769

DOI: 10.1126/science.289.5477.265

PubMed ID: 10997877

Title: Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10997877

DOI: 10.1093/dnares/7.4.271

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 32639996

Title: The membrane protein ANKH is crucial for bone mechanical performance by mediating cellular export of citrate and ATP.

PubMed ID: 32639996

DOI: 10.1371/journal.pgen.1008884

PubMed ID: 35147247

Title: The Mineralization Regulator ANKH Mediates Cellular Efflux of ATP, Not Pyrophosphate.

PubMed ID: 35147247

DOI: 10.1002/jbmr.4528

PubMed ID: 11326338

Title: Autosomal dominant craniometaphyseal dysplasia is caused by mutations in the transmembrane protein ANK.

PubMed ID: 11326338

DOI: 10.1086/320612

PubMed ID: 11326272

Title: Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia.

PubMed ID: 11326272

DOI: 10.1038/ng0501-37

PubMed ID: 12297987

Title: Mutations in ANKH cause chondrocalcinosis.

PubMed ID: 12297987

DOI: 10.1086/343054

PubMed ID: 12297989

Title: Autosomal dominant familial calcium pyrophosphate dihydrate deposition disease is caused by mutation in the transmembrane protein ANKH.

PubMed ID: 12297989

DOI: 10.1086/343053

PubMed ID: 13130483

Title: Mutations in the amino terminus of ANKH in two US families with calcium pyrophosphate dihydrate crystal deposition disease.

PubMed ID: 13130483

DOI: 10.1002/art.11133

PubMed ID: 20943778

Title: Autosomal recessive mental retardation, deafness, ankylosis, and mild hypophosphatemia associated with a novel ANKH mutation in a consanguineous family.

PubMed ID: 20943778

DOI: 10.1210/jc.2010-1539

Sequence Information:

  • Length: 492
  • Mass: 54241
  • Checksum: 44BFEE9089BDEC6B
  • Sequence:
  • MVKFPALTHY WPLIRFLVPL GITNIAIDFG EQALNRGIAA VKEDAVEMLA SYGLAYSLMK 
    FFTGPMSDFK NVGLVFVNSK RDRTKAVLCM VVAGAIAAVF HTLIAYSDLG YYIINKLHHV 
    DESVGSKTRR AFLYLAAFPF MDAMAWTHAG ILLKHKYSFL VGCASISDVI AQVVFVAILL 
    HSHLECREPL LIPILSLYMG ALVRCTTLCL GYYKNIHDII PDRSGPELGG DATIRKMLSF 
    WWPLALILAT QRISRPIVNL FVSRDLGGSS AATEAVAILT ATYPVGHMPY GWLTEIRAVY 
    PAFDKNNPSN KLVSTSNTVT AAHIKKFTFV CMALSLTLCF VMFWTPNVSE KILIDIIGVD 
    FAFAELCVVP LRIFSFFPVP VTVRAHLTGW LMTLKKTFVL APSSVLRIIV LIASLVVLPY 
    LGVHGATLGV GSLLAGFVGE STMVAIAACY VYRKQKKKME NESATEGEDS AMTDMPPTEE 
    VTDIVEMREE NE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.