Details for: Bace2

Gene ID: 56175

Symbol: Bace2

Ensembl ID: ENSMUSG00000040605

Description: beta-site APP-cleaving enzyme 2

Associated with

Other Information

Genular Protein ID: 2828985229

Symbol: BACE2_MOUSE

Name: Beta-secretase 2

UniProtKB Accession Codes:

Q9JL18 Q3TNS7 Q8C5E9 Q8C793 Q9R1P7

Database IDs:

AGR 1 AlphaFoldDB 1 BRENDA 1 BindingDB 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DNASU 1 EC 1 EMBL 8 GO 16 Gene3D 1 GlyCosmos 1 GlyGen 1 InParanoid 1 InterPro 7 KEGG 1 MEROPS 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PRO 1 PROSITE 2 PROSITE-ProRule 2 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10683441

Title: The gene encoding DRAP (BACE2), a glycosylated transmembrane protein of the aspartic protease family, maps to the down critical region.

PubMed ID: 10683441

DOI: 10.1016/s0014-5793(00)01192-3

PubMed ID: 21907142

Title: Bace2 is a beta cell-enriched protease that regulates pancreatic beta cell function and mass.

PubMed ID: 21907142

DOI: 10.1016/j.cmet.2011.06.018

PubMed ID: 23754390

Title: BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells.

PubMed ID: 23754390

DOI: 10.1073/pnas.1220748110

Sequence Information:

  • Length: 514
  • Mass: 55800
  • Checksum: A70725F2C1DF5B47
  • Sequence:
    • MGALLRALLL LVLAQWLLSA VPALAPAPFT LPLQVAGATN HRASAVPGLG TPELPRADGL 
ALALEPVRAT ANFLAMVDNL QGDSGRGYYL EMLIGTPPQK VQILVDTGSS NFAVAGAPHS 
YIDTYFDSES SSTYHSKGFD VTVKYTQGSW TGFVGEDLVT IPKGFNSSFL VNIATIFESE 
NFFLPGIKWN GILGLAYAAL AKPSSSLETF FDSLVAQAKI PDIFSMQMCG AGLPVAGSGT 
NGGSLVLGGI EPSLYKGDIW YTPIKEEWYY QIEILKLEIG GQNLNLDCRE YNADKAIVDS 
GTTLLRLPQK VFDAVVEAVA RTSLIPEFSD GFWTGAQLAC WTNSETPWAY FPKISIYLRD 
ENASRSFRIT ILPQLYIQPM MGAGFNYECY RFGISSSTNA LVIGATVMEG FYVVFDRAQR 
RVGFAVSPCA EIEGTTVSEI SGPFSTEDIA SNCVPAQALN EPILWIVSYA LMSVCGAILL 
VLILLLLLPL HCRHAPRDPE VVNDESSLVR HRWK

Genular Protein ID: 908444061

Symbol: A0A0R4J0I8_MOUSE

Name: N/A

UniProtKB Accession Codes:

A0A0R4J0I8

Database IDs:

AGR 1 ARBA 13 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 Ensembl 2 ExpressionAtlas 1 GO 12 Gene3D 1 GeneTree 1 InterPro 7 KEGG 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSR 3 PRINTS 3 PROSITE 3 Pfam 1 PhylomeDB 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 1 SAM 2 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 514
  • Mass: 55883
  • Checksum: 2A3055EF6AA90230
  • Sequence:
    • MGALLRALLL PVLAQWLLSA VPALAPAPFT LPLQVARATN HRASAVPGLG TPELPRADGL 
ALALEPVRAT ANFLAMVDNL QGDSGRGYYL EMLIGTPPQK VQILVDTGSS NFAVAGAPHS 
YIDTYFDSES SSTYHSKGFD VTVKYTQGSW TGFVGEDLVT IPKGFNSSFL VNIATIFESE 
NFFLPGIKWN GILGLAYAAL AKPSSSLETF FDSLVAQAKI PDIFSMQMCG AGLPVAGSGT 
NGGSLVLGGI EPSLYKGDIW YTPIKEEWYY QIEILKLEIG GQNLNLDCRE YNADKAIVDS 
GTTLLRLPQK VFDAVVEAVA RTSLIPEFSD GFWTGAQLAC WTNSETPWAY FPKISIYLRD 
ENASRSFRIT ILPQLYIQPM MGAGFNYECY RFGISSSTNA LVIGATVMEG FYVVFDRAQR 
RVGFAVSPCA EIEGTTVSEI SGPFSTEDIA SNCVPAQALN EPILWIVSYA LMSVCGAILL 
VLILLLLLPL HCRHAPRDPE VVNDESSLVR HRWK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.