Fxyd1 | ENSMUSG00000036570 | NCBI 56188

Details for: Fxyd1

Gene ID: 56188

Symbol: Fxyd1

Ensembl ID: ENSMUSG00000036570

Description: FXYD domain-containing ion transport regulator 1

Associated with

Cardiac conduction
(R-MMU-5576891)
Ion channel transport
(R-MMU-983712)
Ion homeostasis
(R-MMU-5578775)
Ion transport by p-type atpases
(R-MMU-936837)
Muscle contraction
(R-MMU-397014)
Transport of small molecules
(R-MMU-382551)
Apical plasma membrane
(GO:0016324)
Atpase binding
(GO:0051117)
Caveola
(GO:0005901)
Intercalated disc
(GO:0014704)
Ion channel regulator activity
(GO:0099106)
Membrane
(GO:0016020)
Monoatomic ion transport
(GO:0006811)
Myosin binding
(GO:0017022)
Plasma membrane
(GO:0005886)
Positive regulation of inorganic anion transmembrane transport
(GO:1903797)
Positive regulation of organic acid transport
(GO:0032892)
Positive regulation of sodium ion export across plasma membrane
(GO:1903278)
Potassium ion transport
(GO:0006813)
Regulation of cardiac muscle cell contraction
(GO:0086004)
Regulation of cardiac muscle cell membrane potential
(GO:0086036)
Regulation of cytosolic calcium ion concentration
(GO:0051480)
Regulation of monoatomic ion transport
(GO:0043269)
Regulation of sodium ion transmembrane transporter activity
(GO:2000649)
Sarcolemma
(GO:0042383)
Sodium channel regulator activity
(GO:0017080)
Sodium ion transport
(GO:0006814)
T-tubule
(GO:0030315)

Other Information

Proteins

PLM_MOUSE

Genular Protein ID: 3329188234

Symbol: PLM_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9Z239

Database IDs:

Citations:

PubMed ID: 11410367

Title: Gene structure and expression of phospholemman in mouse.

PubMed ID: 11410367

DOI: 10.1016/s0378-1119(01)00497-8

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15563542

Title: Hypertrophy, increased ejection fraction, and reduced Na-K-ATPase activity in phospholemman-deficient mice.

PubMed ID: 15563542

DOI: 10.1152/ajpheart.00142.2004

PubMed ID: 17283221

Title: The intracellular region of FXYD1 is sufficient to regulate cardiac Na/K ATPase.

PubMed ID: 17283221

DOI: 10.1096/fj.06-7269com

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 18065526

Title: Characterization of the phospholemman knockout mouse heart: depressed left ventricular function with increased Na-K-ATPase activity.

PubMed ID: 18065526

DOI: 10.1152/ajpheart.01332.2007

PubMed ID: 18630941

Title: Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis.

PubMed ID: 18630941

DOI: 10.1021/pr800223m

PubMed ID: 19187398

Title: FXYD1, a modulator of Na,K-ATPase activity, facilitates female sexual development by maintaining gonadotrophin-releasing hormone neuronal excitability.

PubMed ID: 19187398

DOI: 10.1111/j.1365-2826.2008.01812.x

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21454534

Title: FXYD proteins reverse inhibition of the Na+-K+ pump mediated by glutathionylation of its beta1 subunit.

PubMed ID: 21454534

DOI: 10.1074/jbc.m110.184101

PubMed ID: 23532852

Title: A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle.

PubMed ID: 23532852

DOI: 10.1074/jbc.m113.460956

Sequence Information:

Length: 92
Mass: 10323
Checksum: 0BDB1DC83417F3AD
Sequence:

MASPGHILAL CVCLLSMASA EAPQEPDPFT YDYHTLRIGG LTIAGILFIL GILIILSKRC 
RCKFNQQQRT GEPDEEEGTF RSSIRRLSSR RR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fxyd1

Associated with

Other Information

Gene structure and expression of phospholemman in mouse. PubMed ID: 11410367

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Hypertrophy, increased ejection fraction, and reduced Na-K-ATPase activity in phospholemman-deficient mice. PubMed ID: 15563542

The intracellular region of FXYD1 is sufficient to regulate cardiac Na/K ATPase. PubMed ID: 17283221

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

Characterization of the phospholemman knockout mouse heart: depressed left ventricular function with increased Na-K-ATPase activity. PubMed ID: 18065526

Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis. PubMed ID: 18630941

FXYD1, a modulator of Na,K-ATPase activity, facilitates female sexual development by maintaining gonadotrophin-releasing hormone neuronal excitability. PubMed ID: 19187398

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

FXYD proteins reverse inhibition of the Na+-K+ pump mediated by glutathionylation of its beta1 subunit. PubMed ID: 21454534

A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle. PubMed ID: 23532852