Plek | ENSMUSG00000020120 | NCBI 56193

Details for: Plek

Gene ID: 56193

Symbol: Plek

Ensembl ID: ENSMUSG00000020120

Description: pleckstrin

Associated with

Hemostasis
(R-MMU-109582)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet degranulation
(R-MMU-114608)
Response to elevated platelet cytosolic ca2+
(R-MMU-76005)
Actin cytoskeleton organization
(GO:0030036)
Cell projection organization
(GO:0030030)
Cortical actin cytoskeleton organization
(GO:0030866)
Cytoplasm
(GO:0005737)
Integrin-mediated signaling pathway
(GO:0007229)
Intracellular signal transduction
(GO:0035556)
Negative regulation of g protein-coupled receptor signaling pathway
(GO:0045744)
Negative regulation of inositol phosphate biosynthetic process
(GO:0010920)
Phosphatidylinositol-3,4-bisphosphate binding
(GO:0043325)
Phosphatidylinositol metabolic process
(GO:0046488)
Phospholipase c-inhibiting g protein-coupled receptor signaling pathway
(GO:0030845)
Plasma membrane
(GO:0005886)
Platelet aggregation
(GO:0070527)
Positive regulation of actin filament bundle assembly
(GO:0032233)
Positive regulation of actin filament depolymerization
(GO:0030836)
Positive regulation of inositol-polyphosphate 5-phosphatase activity
(GO:0010925)
Positive regulation of integrin activation
(GO:0033625)
Positive regulation of platelet activation
(GO:0010572)
Protein homodimerization activity
(GO:0042803)
Protein kinase c binding
(GO:0005080)
Protein kinase c signaling
(GO:0070528)
Protein secretion by platelet
(GO:0070560)
Regulation of cell diameter
(GO:0060305)
Ruffle membrane
(GO:0032587)
Ruffle organization
(GO:0031529)
Thrombin-activated receptor signaling pathway
(GO:0070493)
Vesicle docking involved in exocytosis
(GO:0006904)

Other Information

Proteins

Pleckstrin

Genular Protein ID: 4108334816

Symbol: PLEK_MOUSE

Name: Pleckstrin

UniProtKB Accession Codes:

Q9JHK5 Q9ERI9

Database IDs:

Citations:

PubMed ID: 10860665

Title: cDNA cloning and mapping of mouse pleckstrin (Plek), a gene upregulated in transformation-resistant cells.

PubMed ID: 10860665

DOI: 10.1006/geno.2000.6210

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 350
Mass: 39901
Checksum: 348F3CB469B7CC53
Sequence:

MEPKRIREGY LVKKGSVFNT WKPMWVVLLE DGIEFYKKKS DNSPKGMIPL KGSTLTSPCQ 
DFGKRMFVLK ITTTKQQDHF FQAAFLEERD AWVRDIKKAI KCIEGGQKFA RKSTRRSIRL 
PETIDLGALY LSMKDPEKGI KELNLEKDKK VFNHCLTGSG VIDWLVSNKL VRNRQEGLMI 
SASLLSEGYL QPAGDLSKNA ADGIAENPFL DSPDAFYYFP DSGFFCEENS SDDDVILREE 
FRGVIIKQGC LLKQGHRRKN WKVRKFILRE DPAYLHYYDP AGGEDPLGAV HLRGCVVTSV 
ESSHDVKKSD EENLFEIITA DEVHYYLQAA TSKERTEWIK AIQVASRTGK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.