Details for: Ptbp2

Gene ID: 56195

Symbol: Ptbp2

Ensembl ID: ENSMUSG00000028134

Description: polypyrimidine tract binding protein 2

Associated with

Other Information

Genular Protein ID: 2777098593

Symbol: PTBP2_MOUSE

Name: Brain-enriched polypyrimidine tract-binding protein

UniProtKB Accession Codes:

Q91Z31 Q7TNW7 Q9CUW2 Q9QYC2 Q9R0V9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 2 CDD 4 CORUM 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 6 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 9 Gene3D 1 GeneTree 1 Genevisible 1 GlyGen 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 2 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 10829067

Title: A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing.

PubMed ID: 10829067

DOI: 10.1073/pnas.110128397

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14667811

Title: Evolutionary conservation of a 2-kb intronic sequence flanking a tissue-specific alternative exon in the PTBP2 gene.

PubMed ID: 14667811

DOI: 10.1016/s0888-7543(03)00207-6

PubMed ID: 11726525

Title: Cell-specific proteins regulate viral RNA translation and virus-induced disease.

PubMed ID: 11726525

DOI: 10.1093/emboj/20.23.6899

PubMed ID: 11231079

Title: Comparative expression analysis of the genes encoding polypyrimidine tract binding protein (PTB) and its neural homologue (brPTB) in prenatal and postnatal mouse brain.

PubMed ID: 11231079

DOI: 10.1016/s0925-4773(00)00566-9

PubMed ID: 12213192

Title: Alternative splicing of brain-specific PTB defines a tissue-specific isoform pattern that predicts distinct functional roles.

PubMed ID: 12213192

DOI: 10.1006/geno.2002.6826

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.m400085-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 30638744

Title: Differential NOVA2-Mediated Splicing in Excitatory and Inhibitory Neurons Regulates Cortical Development and Cerebellar Function.

PubMed ID: 30638744

DOI: 10.1016/j.neuron.2018.12.019

Sequence Information:

  • Length: 531
  • Mass: 57489
  • Checksum: 3A93CA4E3E1D6AA3
  • Sequence:
    • MDGIVTEVAV GVKRGSDELL SGSVLSSPNS NMSGMVVTAN GNDSKKFKGE DKMDGAPSRV 
LHIRKLPGEV TETEVIALGL PFGKVTNILM LKGKNQAFLE LATEEAAITM VNYYSAVTPH 
LRNQPIYIQY SNHKELKTDN TLNQRAQVVL QAVTAVQTAN TPLSGTTVSE SAVTPAQSPV 
LRIIIDNMYY PVTLDVLHQI FSKFGAVLKI ITFTKNNQFQ ALLQYGDPVN AQQAKLALDG 
QNIYNACCTL RIDFSKLVNL NVKYNNDKSR DYTRPDLPSG DGQPALDPAI AAAFAKETSL 
LAVPGALSPL AIPNAAAAAA AAAAGRVGMP GVSAGGNTVL LVSNLNEEMV TPQSLFTLFG 
VYGDVQRVKI LYNKKDSALI QMADGNQSQL AMNHLNGQKM YGKIIRVTLS KHQTVQLPRE 
GLDDQGLTKD FGNSPLHRFK KPGSKNFQNI FPPSATLHLS NIPPSVAEED LRTLFANTGG 
TVKAFKFFQD HKMALLQMAT VEEAIQALID LHNYNLGENH HLRVSFSKST I

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.