Details for: Abcb10

Gene ID: 56199

Symbol: Abcb10

Ensembl ID: ENSMUSG00000031974

Description: ATP-binding cassette, sub-family B member 10

Associated with

Other Information

Genular Protein ID: 8647240

Symbol: ABCBA_MOUSE

Name: ATP-binding cassette transporter 10

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10835348

Title: ABC-me: a novel mitochondrial transporter induced by GATA-1 during erythroid differentiation.

PubMed ID: 10835348

DOI: 10.1093/emboj/19.11.2492

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15215243

Title: Targeting, import, and dimerization of a mammalian mitochondrial ATP binding cassette (ABC) transporter, ABCB10 (ABC-me).

PubMed ID: 15215243

DOI: 10.1074/jbc.m405040200

PubMed ID: 19805291

Title: Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria.

PubMed ID: 19805291

DOI: 10.1073/pnas.0904519106

PubMed ID: 20427704

Title: Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis.

PubMed ID: 20427704

DOI: 10.1182/blood-2009-12-259614

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22240895

Title: The mitochondrial transporter ABC-me (ABCB10), a downstream target of GATA-1, is essential for erythropoiesis in vivo.

PubMed ID: 22240895

DOI: 10.1038/cdd.2011.195

PubMed ID: 24421385

Title: Abcb10 role in heme biosynthesis in vivo: Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation.

PubMed ID: 24421385

DOI: 10.1128/mcb.00865-13

PubMed ID: 26053025

Title: ATP Binding and Hydrolysis Properties of ABCB10 and Their Regulation by Glutathione.

PubMed ID: 26053025

DOI: 10.1371/journal.pone.0129772

PubMed ID: 28808058

Title: Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes.

PubMed ID: 28808058

DOI: 10.1074/jbc.m117.797415

PubMed ID: 30765471

Title: Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis.

PubMed ID: 30765471

DOI: 10.3324/haematol.2018.214320

Sequence Information:

  • Length: 715
  • Mass: 77188
  • Checksum: C07BE44A478B89A2
  • Sequence:
  • MRAPSARALL LIPRRGPAVR AWAPAVSSRI WLASEWTPLV RAWTSLIHKP GSGLRFPAPL 
    SGLPGGVGQW ATSSGARRCW VLAGPRAAHP LFARLQGAAA TGVRDLGNDS QRRPAATGRS 
    EVWKLLGLVR PERGRLSAAV GFLAVSSVIT MSAPFFLGRI IDVIYTNPSE GYGDSLTRLC 
    AVLTCVFLCG AAANGIRVYL MQSSGQSIVN RLRTSLFSSI LRQEVAFFDK TRTGELINRL 
    SSDTALLGRS VTENLSDGLR AGAQASVGVG MMFFVSPSLA TFVLSVVPPI SVLAVIYGRY 
    LRKLSKATQD SLAEATQLAE ERIGNIRTIR AFGKEMTEVE KYTGRVDQLL QLAQKEALAR 
    AGFFGAAGLS GNLIVLSVLY KGGLLMGSAH MTVGELSSFL MYAFWVGLSI GGLSSFYSEL 
    MKGLGAGGRL WELLERQPRL PFNEGMVLDE KTFQGALEFR NVHFTYPARP EVSVFQDFSL 
    SIPSGSVTAL VGPSGSGKST VVSLLLRLYD PNSGTVSLDG HDIRQLNPVW LRSKIGTVSQ 
    EPVLFSCSVA ENIAYGADNL SSVTAQQVER AAEVANAAEF IRSFPQGFDT VVGEKGILLS 
    GGQKQRIAIA RALLKNPKIL LLDEATSALD AENEHLVQEA LDRLMEGRTV LIIAHRLSTI 
    KNANFVAVLD HGKICEHGTH EELLLKPNGL YRKLMNKQSF LSYNGAEQFL EPARA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.