Details for: Becn1
Associated with
Other Information
Genular Protein ID: 670537397
Symbol: BECN1_MOUSE
Name: Beclin-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10604474
Title: Induction of autophagy and inhibition of tumorigenesis by beclin 1.
PubMed ID: 10604474
DOI: 10.1038/45257
PubMed ID: 9765397
Title: Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein.
PubMed ID: 9765397
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12372286
Title: A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice.
PubMed ID: 12372286
PubMed ID: 14657337
Title: Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor.
PubMed ID: 14657337
PubMed ID: 17589504
Title: Ambra1 regulates autophagy and development of the nervous system.
PubMed ID: 17589504
DOI: 10.1038/nature05925
PubMed ID: 19270693
Title: Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.
PubMed ID: 19270693
DOI: 10.1038/ncb1854
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 21364619
Title: Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria.
PubMed ID: 21364619
PubMed ID: 20819940
PubMed ID: 21059846
Title: The class IA phosphatidylinositol 3-kinase p110-beta subunit is a positive regulator of autophagy.
PubMed ID: 21059846
PubMed ID: 22493499
Title: Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex.
PubMed ID: 22493499
PubMed ID: 23332761
Title: Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy.
PubMed ID: 23332761
PubMed ID: 25275521
Title: Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.
PubMed ID: 25275521
PubMed ID: 28445460
Title: Polyglutamine tracts regulate beclin 1-dependent autophagy.
PubMed ID: 28445460
DOI: 10.1038/nature22078
PubMed ID: 29604308
Title: TRIM50 regulates Beclin 1 proautophagic activity.
PubMed ID: 29604308
PubMed ID: 34428398
Title: Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
PubMed ID: 34428398
PubMed ID: 18248095
Title: Structural and biochemical bases for the inhibition of autophagy and apoptosis by viral BCL-2 of murine gamma-herpesvirus 68.
PubMed ID: 18248095
Sequence Information:
- Length: 448
- Mass: 51589
- Checksum: 14623BA002E1AAEE
- Sequence:
MEGSKASSST MQVSFVCQRC SQPLKLDTSF KILDRVTIQE LTAPLLTTAQ AKPGETQEEE ANSGEEPFIE TRQDGVSRRF IPPARMMSTE SANSFTLIGE ASDGGTMENL SRRLKVTGDL FDIMSGQTDV DHPLCEECTD TLLDQLDTQL NVTENECQNY KRCLEILEQM NEDDSEQLQR ELKELALEEE RLIQELEDVE KNRKVVAENL EKVQAEAERL DQEEAQYQRE YSEFKRQQLE LDDELKSVEN QVRYAQIQLD KLKKTNVFNA TFHIWHSGQF GTINNFRLGR LPSVPVEWNE INAAWGQTVL LLHALANKMG LKFQRYRLVP YGNHSYLESL TDKSKELPLY CSGGLRFFWD NKFDHAMVAF LDCVQQFKEE VEKGETRFCL PYRMDVEKGK IEDTGGSGGS YSIKTQFNSE EQWTKALKFM LTNLKWGLAW VSSQFYNK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.