RNF20 | ENSG00000155827 | NCBI 56254

Details for: RNF20

Gene ID: 56254

Symbol: RNF20

Ensembl ID: ENSG00000155827

Description: ring finger protein 20

Associated with

E3 ubiquitin ligases ubiquitinate target proteins
(R-HSA-8866654)
Metabolism of proteins
(R-HSA-392499)
Post-translational protein modification
(R-HSA-597592)
Protein ubiquitination
(R-HSA-8852135)
Rhobtb1 gtpase cycle
(R-HSA-9013422)
Rhobtb gtpase cycle
(R-HSA-9706574)
Rho gtpase cycle
(R-HSA-9012999)
Signaling by rho gtpases
(R-HSA-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Signal transduction
(R-HSA-162582)
Chromatin binding
(GO:0003682)
Chromatin remodeling
(GO:0006338)
Histone binding
(GO:0042393)
Histone h2b c-terminal k residue ubiquitin ligase activity
(GO:0140850)
Hulc complex
(GO:0033503)
Identical protein binding
(GO:0042802)
Metal ion binding
(GO:0046872)
Mrna 3'-utr binding
(GO:0003730)
Negative regulation of cell migration
(GO:0030336)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
P53 binding
(GO:0002039)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Protein polyubiquitination
(GO:0000209)
Regulation of dna-templated transcription
(GO:0006355)
Regulation of mitotic cell cycle
(GO:0007346)
Transcription coactivator activity
(GO:0003713)
Ubiquitin-dependent protein catabolic process
(GO:0006511)
Ubiquitin-protein transferase activity
(GO:0004842)
Ubiquitin ligase complex
(GO:0000151)
Ubiquitin protein ligase activity
(GO:0061630)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

E3 ubiquitin-protein ligase BRE1A

Genular Protein ID: 2622475559

Symbol: BRE1A_HUMAN

Name: E3 ubiquitin-protein ligase BRE1A

UniProtKB Accession Codes:

Q5VTR2 A7MCT5 Q2TB34 Q69YL5 Q6P527 Q8N3J4 Q96JD3 Q9H9Y7 Q9HA51 Q9NUR4 Q9NWQ3 Q9NX83

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16307923

Title: Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation.

PubMed ID: 16307923

DOI: 10.1016/j.molcel.2005.09.025

PubMed ID: 16337599

Title: The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions.

PubMed ID: 16337599

DOI: 10.1016/j.molcel.2005.11.012

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19410543

Title: RAD6-mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells.

PubMed ID: 19410543

DOI: 10.1016/j.cell.2009.02.027

PubMed ID: 19037095

Title: Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor.

PubMed ID: 19037095

DOI: 10.1091/mbc.e08-09-0983

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21329877

Title: WAC, a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcription.

PubMed ID: 21329877

DOI: 10.1016/j.molcel.2011.01.024

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

Length: 975
Mass: 113662
Checksum: D75C7BE02880594A
Sequence:

MSGIGNKRAA GEPGTSMPPE KKAAVEDSGT TVETIKLGGV SSTEELDIRT LQTKNRKLAE 
MLDQRQAIED ELREHIEKLE RRQATDDASL LIVNRYWSQF DENIRIILKR YDLEQGLGDL 
LTERKALVVP EPEPDSDSNQ ERKDDRERGE GQEPAFSFLA TLASSSSEEM ESQLQERVES 
SRRAVSQIVT VYDKLQEKVE LLSRKLNSGD NLIVEEAVQE LNSFLAQENM RLQELTDLLQ 
EKHRTMSQEF SKLQSKVETA ESRVSVLESM IDDLQWDIDK IRKREQRLNR HLAEVLERVN 
SKGYKVYGAG SSLYGGTITI NARKFEEMNA ELEENKELAQ NRLCELEKLR QDFEEVTTQN 
EKLKVELRSA VEQVVKETPE YRCMQSQFSV LYNESLQLKA HLDEARTLLH GTRGTHQHQV 
ELIERDEVSL HKKLRTEVIQ LEDTLAQVRK EYEMLRIEFE QTLAANEQAG PINREMRHLI 
SSLQNHNHQL KGEVLRYKRK LREAQSDLNK TRLRSGSALL QSQSSTEDPK DEPAELKPDS 
EDLSSQSSAS KASQEDANEI KSKRDEEERE RERREKERER EREREKEKER EREKQKLKES 
EKERDSAKDK EKGKHDDGRK KEAEIIKQLK IELKKAQESQ KEMKLLLDMY RSAPKEQRDK 
VQLMAAEKKS KAELEDLRQR LKDLEDKEKK ENKKMADEDA LRKIRAVEEQ IEYLQKKLAM 
AKQEEEALLS EMDVTGQAFE DMQEQNIRLM QQLREKDDAN FKLMSERIKS NQIHKLLKEE 
KEELADQVLT LKTQVDAQLQ VVRKLEEKEH LLQSNIGTGE KELGLRTQAL EMNKRKAMEA 
AQLADDLKAQ LELAQKKLHD FQDEIVENSV TKEKDMFNFK RAQEDISRLR RKLETTKKPD 
NVPKCDEILM EEIKDYKARL TCPCCNMRKK DAVLTKCFHV FCFECVKTRY DTRQRKCPKC 
NAAFGANDFH RIYIG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: RNF20

Associated with

Other Information

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

DNA sequence and analysis of human chromosome 9. PubMed ID: 15164053

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. PubMed ID: 16307923

The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions. PubMed ID: 16337599

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. PubMed ID: 17081983

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. PubMed ID: 17525332

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

RAD6-mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. PubMed ID: 19410543

Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor. PubMed ID: 19037095

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

WAC, a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcription. PubMed ID: 21329877

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569