AZGP1 | ENSG00000160862 | NCBI 563

Details for: AZGP1

Gene ID: 563

Symbol: AZGP1

Ensembl ID: ENSG00000160862

Description: alpha-2-glycoprotein 1, zinc-binding

Associated with

Miscellaneous transport and binding events
(R-HSA-5223345)
Transport of small molecules
(R-HSA-382551)
Cell adhesion
(GO:0007155)
Collagen-containing extracellular matrix
(GO:0062023)
Detection of chemical stimulus involved in sensory perception of bitter taste
(GO:0001580)
External side of plasma membrane
(GO:0009897)
Extracellular exosome
(GO:0070062)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Immune response
(GO:0006955)
Negative regulation of cell population proliferation
(GO:0008285)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Protein transmembrane transport
(GO:0071806)
Protein transmembrane transporter activity
(GO:0008320)
Rna nuclease activity
(GO:0004540)

Other Information

Proteins

Zinc-alpha-2-glycoprotein

Genular Protein ID: 258717831

Symbol: ZA2G_HUMAN

Name: Zinc-alpha-2-glycoprotein

UniProtKB Accession Codes:

P25311 D6W5T8 O60386 Q5XKQ4 Q8N4N0

Database IDs:

Citations:

PubMed ID: 1915885

Title: Human Zn-alpha 2-glycoprotein cDNA cloning and expression analysis in benign and malignant breast tissues.

PubMed ID: 1915885

DOI: 10.1016/0014-5793(91)81271-9

PubMed ID: 8241150

Title: Molecular cloning and chromosomal assignment of the gene for human Zn-alpha 2-glycoprotein.

PubMed ID: 8241150

DOI: 10.1021/bi00211a004

PubMed ID: 8307568

Title: Human Zn-alpha 2-glycoprotein: complete genomic sequence, identification of a related pseudogene and relationship to class I major histocompatibility complex genes.

PubMed ID: 8307568

DOI: 10.1016/s0888-7543(05)80359-3

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2049092

Title: Cloning and nucleotide sequence of a human Zn-alpha 2-glycoprotein cDNA and chromosomal assignment of its gene.

PubMed ID: 2049092

DOI: 10.1016/0006-291x(91)91844-3

PubMed ID: 3422450

Title: Complete amino acid sequence of human plasma Zn-alpha 2-glycoprotein and its homology to histocompatibility antigens.

PubMed ID: 3422450

DOI: 10.1073/pnas.85.3.679

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 9114041

Title: Biochemical characterization and crystallization of human Zn-alpha2-glycoprotein, a soluble class I major histocompatibility complex homolog.

PubMed ID: 9114041

DOI: 10.1073/pnas.94.9.4626

PubMed ID: 11425849

Title: Hydrophobic ligand binding by Zn-alpha 2-glycoprotein, a soluble fat-depleting factor related to major histocompatibility complex proteins.

PubMed ID: 11425849

DOI: 10.1074/jbc.c100301200

PubMed ID: 15084671

Title: A proteomic analysis of human bile.

PubMed ID: 15084671

DOI: 10.1074/mcp.m400015-mcp200

PubMed ID: 14760718

Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.

PubMed ID: 14760718

DOI: 10.1002/pmic.200300556

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 16740002

Title: Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.

PubMed ID: 16740002

DOI: 10.1021/pr050492k

PubMed ID: 18780401

Title: Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry.

PubMed ID: 18780401

DOI: 10.1002/pmic.200701057

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 22171320

Title: Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD.

PubMed ID: 22171320

DOI: 10.1074/mcp.m111.013649

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 10206894

Title: Crystal structure of human ZAG, a fat-depleting factor related to MHC molecules.

PubMed ID: 10206894

DOI: 10.1126/science.283.5409.1914

PubMed ID: 15477100

Title: Crystallographic studies of ligand binding by Zn-alpha2-glycoprotein.

PubMed ID: 15477100

DOI: 10.1016/j.jsb.2004.04.009

PubMed ID: 18930737

Title: Crystal structure of the novel complex formed between zinc alpha2-glycoprotein (ZAG) and prolactin-inducible protein (PIP) from human seminal plasma.

PubMed ID: 18930737

DOI: 10.1016/j.jmb.2008.09.072

Sequence Information:

Length: 298
Mass: 34259
Checksum: 006A153A8E32A0B1
Sequence:

MVRMVPVLLS LLLLLGPAVP QENQDGRYSL TYIYTGLSKH VEDVPAFQAL GSLNDLQFFR 
YNSKDRKSQP MGLWRQVEGM EDWKQDSQLQ KAREDIFMET LKDIVEYYND SNGSHVLQGR 
FGCEIENNRS SGAFWKYYYD GKDYIEFNKE IPAWVPFDPA AQITKQKWEA EPVYVQRAKA 
YLEEECPATL RKYLKYSKNI LDRQDPPSVV VTSHQAPGEK KKLKCLAYDF YPGKIDVHWT 
RAGEVQEPEL RGDVLHNGNG TYQSWVVVAV PPQDTAPYSC HVQHSSLAQP LVVPWEAS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: AZGP1

Associated with

Other Information

Human Zn-alpha 2-glycoprotein cDNA cloning and expression analysis in benign and malignant breast tissues. PubMed ID: 1915885

Molecular cloning and chromosomal assignment of the gene for human Zn-alpha 2-glycoprotein. PubMed ID: 8241150

Human Zn-alpha 2-glycoprotein: complete genomic sequence, identification of a related pseudogene and relationship to class I major histocompatibility complex genes. PubMed ID: 8307568

The DNA sequence of human chromosome 7. PubMed ID: 12853948

Human chromosome 7: DNA sequence and biology. PubMed ID: 12690205

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Cloning and nucleotide sequence of a human Zn-alpha 2-glycoprotein cDNA and chromosomal assignment of its gene. PubMed ID: 2049092

Complete amino acid sequence of human plasma Zn-alpha 2-glycoprotein and its homology to histocompatibility antigens. PubMed ID: 3422450

Signal peptide prediction based on analysis of experimentally verified cleavage sites. PubMed ID: 15340161

Biochemical characterization and crystallization of human Zn-alpha2-glycoprotein, a soluble class I major histocompatibility complex homolog. PubMed ID: 9114041

Hydrophobic ligand binding by Zn-alpha 2-glycoprotein, a soluble fat-depleting factor related to major histocompatibility complex proteins. PubMed ID: 11425849

A proteomic analysis of human bile. PubMed ID: 15084671

Screening for N-glycosylated proteins by liquid chromatography mass spectrometry. PubMed ID: 14760718

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. PubMed ID: 16335952

Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. PubMed ID: 16740002

Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry. PubMed ID: 18780401

Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. PubMed ID: 19159218

A strategy for precise and large scale identification of core fucosylated glycoproteins. PubMed ID: 19139490

Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD. PubMed ID: 22171320

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Crystal structure of human ZAG, a fat-depleting factor related to MHC molecules. PubMed ID: 10206894

Crystallographic studies of ligand binding by Zn-alpha2-glycoprotein. PubMed ID: 15477100

Crystal structure of the novel complex formed between zinc alpha2-glycoprotein (ZAG) and prolactin-inducible protein (PIP) from human seminal plasma. PubMed ID: 18930737