Details for: AZGP1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 129.8658
Cell Significance Index: -20.2000 - Cell Name: epithelial cell of exocrine pancreas (CL1001433)
Fold Change: 65.4107
Cell Significance Index: 32.8500 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 42.7302
Cell Significance Index: 262.9700 - Cell Name: salivary gland glandular cell (CL1001596)
Fold Change: 35.8768
Cell Significance Index: 199.6900 - Cell Name: liver dendritic cell (CL2000055)
Fold Change: 25.7094
Cell Significance Index: 67.8200 - Cell Name: epithelial cell of sweat gland (CL1000448)
Fold Change: 25.2294
Cell Significance Index: 18.0300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 24.4068
Cell Significance Index: 1137.9600 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: 22.3416
Cell Significance Index: 465.9500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 13.0731
Cell Significance Index: 974.3300 - Cell Name: endothelial tip cell (CL0000704)
Fold Change: 12.4331
Cell Significance Index: 53.4700 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 7.1656
Cell Significance Index: 120.7100 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 6.9517
Cell Significance Index: 71.9400 - Cell Name: mucus secreting cell of tracheobronchial tree submucosal gland (CL4033037)
Fold Change: 6.6985
Cell Significance Index: 44.7300 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 5.6583
Cell Significance Index: 34.9100 - Cell Name: lactocyte (CL0002325)
Fold Change: 4.6297
Cell Significance Index: 598.1300 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 4.5014
Cell Significance Index: 45.4100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 4.3758
Cell Significance Index: -13.4400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 3.7367
Cell Significance Index: 175.6200 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 3.5002
Cell Significance Index: 29.7500 - Cell Name: sebaceous gland cell (CL2000021)
Fold Change: 2.4406
Cell Significance Index: 3.1600 - Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
Fold Change: 2.4193
Cell Significance Index: 24.2100 - Cell Name: hepatoblast (CL0005026)
Fold Change: 2.3473
Cell Significance Index: 39.4800 - Cell Name: airway submucosal gland collecting duct epithelial cell (CL4033023)
Fold Change: 2.2913
Cell Significance Index: 16.0800 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 1.7061
Cell Significance Index: 9.8300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.6239
Cell Significance Index: 176.6300 - Cell Name: mammary gland epithelial cell (CL0002327)
Fold Change: 1.3901
Cell Significance Index: 6.4000 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 1.3726
Cell Significance Index: 20.2600 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 1.2798
Cell Significance Index: 22.6200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.1502
Cell Significance Index: 69.0500 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.9207
Cell Significance Index: 25.0600 - Cell Name: intrahepatic cholangiocyte (CL0002538)
Fold Change: 0.9054
Cell Significance Index: 3.4100 - Cell Name: epithelial cell of lacrimal sac (CL1000436)
Fold Change: 0.8991
Cell Significance Index: 6.4700 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 0.8693
Cell Significance Index: 5.3800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.8153
Cell Significance Index: 56.3900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.7471
Cell Significance Index: 142.1800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.6807
Cell Significance Index: 116.2400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6325
Cell Significance Index: 102.8800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.4021
Cell Significance Index: 79.8000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1603
Cell Significance Index: 15.8600 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1538
Cell Significance Index: 4.4300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1319
Cell Significance Index: 23.7800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0899
Cell Significance Index: 68.0100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0817
Cell Significance Index: 9.5200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0808
Cell Significance Index: 2.8400 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: 0.0699
Cell Significance Index: 0.8800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0507
Cell Significance Index: 6.2400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0132
Cell Significance Index: 1.0200 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: 0.0048
Cell Significance Index: 0.2100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0064
Cell Significance Index: -0.2900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0103
Cell Significance Index: -19.3900 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: -0.0132
Cell Significance Index: -0.1700 - Cell Name: mucous neck cell (CL0000651)
Fold Change: -0.0147
Cell Significance Index: -0.0700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0187
Cell Significance Index: -34.4300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0223
Cell Significance Index: -34.4000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0235
Cell Significance Index: -17.2000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0252
Cell Significance Index: -16.0200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0253
Cell Significance Index: -34.3700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0273
Cell Significance Index: -17.0600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0278
Cell Significance Index: -20.6200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0303
Cell Significance Index: -13.4000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0306
Cell Significance Index: -8.8000 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0358
Cell Significance Index: -19.5600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0368
Cell Significance Index: -20.7600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0406
Cell Significance Index: -1.3000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0438
Cell Significance Index: -15.7000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0447
Cell Significance Index: -4.5700 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0509
Cell Significance Index: -23.1100 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0744
Cell Significance Index: -3.7600 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0821
Cell Significance Index: -10.5300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0918
Cell Significance Index: -18.4300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1009
Cell Significance Index: -11.5600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1092
Cell Significance Index: -23.0000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.1164
Cell Significance Index: -2.9100 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1205
Cell Significance Index: -2.5000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1346
Cell Significance Index: -19.5700 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1395
Cell Significance Index: -2.9700 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.1443
Cell Significance Index: -2.1800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.1495
Cell Significance Index: -20.5300 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.1538
Cell Significance Index: -2.3800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1718
Cell Significance Index: -20.2600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1833
Cell Significance Index: -14.5200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2017
Cell Significance Index: -21.0100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.2135
Cell Significance Index: -15.1000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2559
Cell Significance Index: -16.1300 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: -0.2564
Cell Significance Index: -1.9600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.2586
Cell Significance Index: -17.3900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.2613
Cell Significance Index: -5.6600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2644
Cell Significance Index: -16.2100 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.2767
Cell Significance Index: -11.3400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.2801
Cell Significance Index: -14.5500 - Cell Name: peptic cell (CL0000155)
Fold Change: -0.3089
Cell Significance Index: -2.7500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.3229
Cell Significance Index: -19.8500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.3439
Cell Significance Index: -9.6100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3896
Cell Significance Index: -21.8600 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.3969
Cell Significance Index: -14.5700 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.4212
Cell Significance Index: -12.0800 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.4627
Cell Significance Index: -6.6300 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -0.4723
Cell Significance Index: -7.1700 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.4753
Cell Significance Index: -11.8700 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.4756
Cell Significance Index: -11.5200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 258717831
Symbol: ZA2G_HUMAN
Name: Zinc-alpha-2-glycoprotein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1915885
Title: Human Zn-alpha 2-glycoprotein cDNA cloning and expression analysis in benign and malignant breast tissues.
PubMed ID: 1915885
PubMed ID: 8241150
Title: Molecular cloning and chromosomal assignment of the gene for human Zn-alpha 2-glycoprotein.
PubMed ID: 8241150
DOI: 10.1021/bi00211a004
PubMed ID: 8307568
Title: Human Zn-alpha 2-glycoprotein: complete genomic sequence, identification of a related pseudogene and relationship to class I major histocompatibility complex genes.
PubMed ID: 8307568
PubMed ID: 12853948
PubMed ID: 12690205
Title: Human chromosome 7: DNA sequence and biology.
PubMed ID: 12690205
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2049092
Title: Cloning and nucleotide sequence of a human Zn-alpha 2-glycoprotein cDNA and chromosomal assignment of its gene.
PubMed ID: 2049092
PubMed ID: 3422450
Title: Complete amino acid sequence of human plasma Zn-alpha 2-glycoprotein and its homology to histocompatibility antigens.
PubMed ID: 3422450
PubMed ID: 15340161
Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.
PubMed ID: 15340161
DOI: 10.1110/ps.04682504
PubMed ID: 9114041
Title: Biochemical characterization and crystallization of human Zn-alpha2-glycoprotein, a soluble class I major histocompatibility complex homolog.
PubMed ID: 9114041
PubMed ID: 11425849
Title: Hydrophobic ligand binding by Zn-alpha 2-glycoprotein, a soluble fat-depleting factor related to major histocompatibility complex proteins.
PubMed ID: 11425849
PubMed ID: 15084671
PubMed ID: 14760718
Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.
PubMed ID: 14760718
PubMed ID: 16335952
Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
PubMed ID: 16335952
DOI: 10.1021/pr0502065
PubMed ID: 16740002
Title: Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.
PubMed ID: 16740002
DOI: 10.1021/pr050492k
PubMed ID: 18780401
Title: Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry.
PubMed ID: 18780401
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 19139490
Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.
PubMed ID: 19139490
PubMed ID: 22171320
Title: Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD.
PubMed ID: 22171320
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 10206894
Title: Crystal structure of human ZAG, a fat-depleting factor related to MHC molecules.
PubMed ID: 10206894
PubMed ID: 15477100
Title: Crystallographic studies of ligand binding by Zn-alpha2-glycoprotein.
PubMed ID: 15477100
PubMed ID: 18930737
Title: Crystal structure of the novel complex formed between zinc alpha2-glycoprotein (ZAG) and prolactin-inducible protein (PIP) from human seminal plasma.
PubMed ID: 18930737
Sequence Information:
- Length: 298
- Mass: 34259
- Checksum: 006A153A8E32A0B1
- Sequence:
MVRMVPVLLS LLLLLGPAVP QENQDGRYSL TYIYTGLSKH VEDVPAFQAL GSLNDLQFFR YNSKDRKSQP MGLWRQVEGM EDWKQDSQLQ KAREDIFMET LKDIVEYYND SNGSHVLQGR FGCEIENNRS SGAFWKYYYD GKDYIEFNKE IPAWVPFDPA AQITKQKWEA EPVYVQRAKA YLEEECPATL RKYLKYSKNI LDRQDPPSVV VTSHQAPGEK KKLKCLAYDF YPGKIDVHWT RAGEVQEPEL RGDVLHNGNG TYQSWVVVAV PPQDTAPYSC HVQHSSLAQP LVVPWEAS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.